CCG-232601
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- $109 - $617
- Product name: CCG-232601
- CAS: 1922099-21-5
- MF: C24H20ClF2N3O2
- MW: 455.88
- EINECS:
- MDL Number:MFCD31812420
- Synonyms:CCG-232601;CCG-232601 (CCG232601);3-Piperidinecarboxamide, N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-;N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-3-piperidinecarboxamide
5 prices
Selected condition：
Brand
- AK Scientific
- Axon Medchem
- Cayman Chemical
Package
- 1mg
- 5mg
- ManufacturerAK Scientific
- Product number5832EG
- Product descriptionN-(4-Chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide
- Packaging1mg
- Price$214
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number5832EG
- Product descriptionN-(4-Chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide
- Packaging5mg
- Price$617
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2753
- Product descriptionCCG232601 99%
- Packaging5mg
- Price$176
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number24382
- Product descriptionCCG-232601 ≥98%
- Packaging1mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24382
- Product descriptionCCG-232601 ≥98%
- Packaging5mg
- Price$481
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 5832EG | N-(4-Chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide | 1mg | $214 | 2021-12-16 | Buy |
| AK Scientific | 5832EG | N-(4-Chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide | 5mg | $617 | 2021-12-16 | Buy |
| Axon Medchem | Axon2753 | CCG232601 99% | 5mg | $176 | 2021-12-16 | Buy |
| Cayman Chemical | 24382 | CCG-232601 ≥98% | 1mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 24382 | CCG-232601 ≥98% | 5mg | $481 | 2024-03-01 | Buy |
Properties
Boiling point :683.1±55.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
form :A crystalline solid
pka :13.69±0.70(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
form :A crystalline solid
pka :13.69±0.70(Predicted)
Safety Information
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Description
CCG-232601 is an inhibitor of the Rho/MRTF/SRF transcriptional pathway and a derivative of CCG-203971 . CCG-232601 inhibits MRTF-dependent transcription in HEK293T cells (IC50 = 0.55 μM in a luciferase reporter assay). It also reduces expression of α-smooth muscle actin (α-SMA) in TGF-β-stimulated human dermal fibroblasts to 31% of control when used at a concentration of 10 μM. CCG-232601 (50 mg/kg) inhibits increases in dermal thickness and hydroxyproline content in a mouse model of dermal fibrosis induced by bleomycin .Suppliers and manufacturers
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