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ChemicalBook >> CAS DataBase List >> CD437

CD437

CD437 price.
  • $60 - $2100
  • Product name: CD437
  • CAS: 125316-60-1
  • MF: C27H26O3
  • MW: 398.49
  • EINECS:200-258-5
  • MDL Number:MFCD03106506
  • Synonyms:2-naphthalenecarboxylicacid,6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphen ;6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphenyl)-2-naphthalenecarboxylic ;AHPN, 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid;O-DesMethyl Adapalene;CD 437/AHPN;Adapalene IMpurity F;Apoptosis Activator VI, CD437/AHPN ;ADAP-IME
32 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250MG
  • 1g
  • ManufacturerAK Scientific
  • Product number4426BA
  • Product description6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylicAcid
  • Packaging1g
  • Price$2085
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA570556
  • Product descriptionCD-437 98+%
  • Packaging5mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA570556
  • Product descriptionCD-437 98+%
  • Packaging10mg
  • Price$156
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA570556
  • Product descriptionCD-437 98+%
  • Packaging25mg
  • Price$265
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA570556
  • Product descriptionCD-437 98+%
  • Packaging100mg
  • Price$584
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0294494
  • Product descriptionO-DESMETHYL ADAPALENE 95.00%
  • Packaging25MG
  • Price$739.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0294494
  • Product descriptionO-DESMETHYL ADAPALENE 95.00%
  • Packaging250MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6785
  • Product descriptionCD437
  • Packaging5mg
  • Price$126
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB6785
  • Product descriptionCD437
  • Packaging10mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6785
  • Product descriptionCD437
  • Packaging25mg
  • Price$410
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6785
  • Product descriptionCD437
  • Packaging50mg
  • Price$725
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6785
  • Product descriptionCD437
  • Packaging100mg
  • Price$1292
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD21233
  • Product descriptionO-Desmethyl adapalene
  • Packaging10mg
  • Price$139.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD21233
  • Product descriptionO-Desmethyl adapalene
  • Packaging25mg
  • Price$254.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD21233
  • Product descriptionO-Desmethyl adapalene
  • Packaging50mg
  • Price$462
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD21233
  • Product descriptionO-Desmethyl adapalene
  • Packaging100mg
  • Price$840
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4426BA 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylicAcid 1g $2085 2021-12-16 Buy
Ambeed A570556 CD-437 98+% 5mg $112 2021-12-16 Buy
Ambeed A570556 CD-437 98+% 10mg $156 2021-12-16 Buy
Ambeed A570556 CD-437 98+% 25mg $265 2021-12-16 Buy
Ambeed A570556 CD-437 98+% 100mg $584 2021-12-16 Buy
American Custom Chemicals Corporation CHM0294494 O-DESMETHYL ADAPALENE 95.00% 25MG $739.2 2021-12-16 Buy
American Custom Chemicals Corporation CHM0294494 O-DESMETHYL ADAPALENE 95.00% 250MG $1871.1 2021-12-16 Buy
ApexBio Technology B6785 CD437 5mg $126 2021-12-16 Buy
ApexBio Technology B6785 CD437 10mg $189 2021-12-16 Buy
ApexBio Technology B6785 CD437 25mg $410 2021-12-16 Buy
ApexBio Technology B6785 CD437 50mg $725 2021-12-16 Buy
ApexBio Technology B6785 CD437 100mg $1292 2021-12-16 Buy
Biosynth Carbosynth FD21233 O-Desmethyl adapalene 10mg $139.8 2021-12-16 Buy
Biosynth Carbosynth FD21233 O-Desmethyl adapalene 25mg $254.5 2021-12-16 Buy
Biosynth Carbosynth FD21233 O-Desmethyl adapalene 50mg $462 2021-12-16 Buy
Biosynth Carbosynth FD21233 O-Desmethyl adapalene 100mg $840 2021-12-16 Buy

Properties

Melting point :271.6-276 °C
Boiling point :595.0±50.0 °C(Predicted)
Density :1.290
storage temp. :-20°C
solubility :DMSO: 26 mg/mL
form :solid
pka :4.17±0.30(Predicted)
color :yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P281 Use personal protective equipment as required.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

CD437 is the prototypical adamantyl arotinoid of the retinoid-related molecule family that acts as a selective agonist of retinoic acid receptor (RAR)γ (Kds = 6.5 μM, 2.5 μM, and 77 nM for RARα, β, and γ, respectively). CD437 is cytotoxic to the acute myeloid leukemia cell line NB4 (EC50 = 0.17 μM), inducing DNA damage by producing DNA double strand breaks. CD437 also induces cell cycle arrest and apoptosis in various other cancer cells including melanoma, breast, non-small lung, and prostate cancer cells through RAR-dependent and -independent signaling pathways.

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