CGP 57380
- $32 - $5034
- Product name: CGP 57380
- CAS: 522629-08-9
- MF: C11H9FN6
- MW: 244.23
- EINECS:
- MDL Number:MFCD03861062
- Synonyms:CGP 57380;CGP57380, N3-(4-fluorophenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,4-diamine;MNK1 Inhibitor;N3-(4-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine;CGP57380; CGP-57380;CS-1420;MNK1 Inhibitor - CAS 522629-08-9 - Calbiochem;P 57380
42 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 1
- 100mg
- 250mg
- 50
- 1g
- 10mM(in 1mL DMSO)
- 1000mg
- ManufacturerAK Scientific
- Product number2314AH
- Product description3-N-(4-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine
- Packaging1mg
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA151588
- Product descriptionCGP 57380 98+%
- Packaging1mg
- Price$32
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA151588
- Product descriptionCGP 57380 98+%
- Packaging5mg
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA151588
- Product descriptionCGP 57380 98+%
- Packaging10mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA151588
- Product descriptionCGP 57380 98+%
- Packaging50mg
- Price$493
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA151588
- Product descriptionCGP 57380 98+%
- Packaging100mg
- Price$839
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA151588
- Product descriptionCGP 57380 98+%
- Packaging250mg
- Price$1678
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA151588
- Product descriptionCGP 57380 98+%
- Packaging1g
- Price$5034
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000072
- Product descriptionCGP 57380 95.00%
- Packaging1MG
- Price$148.05
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000072
- Product descriptionCGP 57380 95.00%
- Packaging10MG
- Price$721.59
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000072
- Product descriptionCGP 57380 95.00%
- Packaging50MG
- Price$1327.97
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3570
- Product descriptionCGP 57380
- Packaging10mM(in 1mL DMSO)
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3570
- Product descriptionCGP 57380
- Packaging5mg
- Price$81
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3570
- Product descriptionCGP 57380
- Packaging10mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0182
- Product descriptionCGP 57380
- Packaging1mg
- Price$58
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0182
- Product descriptionCGP 57380
- Packaging5mg
- Price$131
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2314AH | 3-N-(4-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine | 1mg | $105 | 2021-12-16 | Buy |
Ambeed | A151588 | CGP 57380 98+% | 1mg | $32 | 2021-12-16 | Buy |
Ambeed | A151588 | CGP 57380 98+% | 5mg | $79 | 2021-12-16 | Buy |
Ambeed | A151588 | CGP 57380 98+% | 10mg | $135 | 2021-12-16 | Buy |
Ambeed | A151588 | CGP 57380 98+% | 50mg | $493 | 2021-12-16 | Buy |
Ambeed | A151588 | CGP 57380 98+% | 100mg | $839 | 2021-12-16 | Buy |
Ambeed | A151588 | CGP 57380 98+% | 250mg | $1678 | 2021-12-16 | Buy |
Ambeed | A151588 | CGP 57380 98+% | 1g | $5034 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000072 | CGP 57380 95.00% | 1MG | $148.05 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000072 | CGP 57380 95.00% | 10MG | $721.59 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000072 | CGP 57380 95.00% | 50MG | $1327.97 | 2021-12-16 | Buy |
ApexBio Technology | B3570 | CGP 57380 | 10mM(in 1mL DMSO) | $60 | 2021-12-16 | Buy |
ApexBio Technology | B3570 | CGP 57380 | 5mg | $81 | 2021-12-16 | Buy |
ApexBio Technology | B3570 | CGP 57380 | 10mg | $130 | 2021-12-16 | Buy |
Apolloscientific | BISN0182 | CGP 57380 | 1mg | $58 | 2021-12-16 | Buy |
Apolloscientific | BISN0182 | CGP 57380 | 5mg | $131 | 2021-12-16 | Buy |
Properties
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
color :white to beige
solubility :DMSO: soluble10mg/mL, clear
form :powder
color :white to beige
Safety Information
Symbol(GHS): | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | ||||||||||||||
Hazard statements: |
|
||||||||||||||
Precautionary statements: |
|
Description
CGP 57380 is a selective inhibitor of MAP kinase-interacting kinase 1 (MNK1) in vitro (IC50 = 2.2 μM), with no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases. It blocks the phosphorylation of eIF4E in response to TNF-α, arsenite, anisomycin, PMA, or fetal calf serum in 293 cells (IC50 = 3 μM). CGP 57380 also dose-dependently inhibits TNF-α production in RAW 264.7 cells that have been co-treated with agonists for Toll-like receptor (TLR)2 (HKLM), TLR4 (LPS), TLR6/2 (FSL), TLR7 (imiquimod), or TLR9 (CpG DNA), presumably by inhibiting MNK1.More related product prices
Erlotinib hydrochloride Vorinostat Gemcitabine Fludarabine 1H-BenzotriazoleRelated product price
- Erlotinib hydrochloride
$5-3498.6 - Vorinostat
$8-3980 - Gemcitabine
$6-6080
Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
CONIER CHEM AND PHARMA LIMITED
Shaanxi Dideu Medichem Co. Ltd
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd