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ChemicalBook >> CAS DataBase List >> CHIR-090

CHIR-090

CHIR-090 price.
  • $57 - $2299
  • Product name: CHIR-090
  • CAS: 728865-23-4
  • MF: C24H27N3O5
  • MW: 437.49
  • EINECS:
  • MDL Number:MFCD22665727
  • Synonyms:CHIR-090;N-[(1S,2R)-2-Hydroxy-1-[(hydroxyamino)carbonyl]propyl]-4-[[4-(4-morpholinylmethyl)phenyl]ethynyl]benzamide;N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]benzamide;CHIR-090 (CHIR 090;CS-2285;Benzamide, N-[(1S,2R)-2-hydroxy-1-[(hydroxyamino)carbonyl]propyl]-4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]-;N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[2-[4-(morphChemicalbookolin-4-ylmethyl)phenyl]ethynyl]benzamide;N-((2S,3R)-3-Hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl)-4-((4-(morpholinomethyl)phenyl)ethynyl)benzamide
Price20 Properties Safety Information Description
20 prices
Selected condition：
Brand
  • Activate Scientific
  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 1g
  • ManufacturerActivate Scientific
  • Product numberAS111888
  • Product descriptionCHIR-090 98%
  • Packaging5mg
  • Price$204
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS111888
  • Product descriptionCHIR-090 98%
  • Packaging25mg
  • Price$535
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3541AH
  • Product descriptionN-[(1S,2R)-2-Hydroxy-1-[(hydroxyamino)carbonyl]propyl]-4-[[4-(4-morpholinylmethyl)phenyl]ethynyl]benzamide
  • Packaging5mg
  • Price$227
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3307
  • Product descriptionCHIR-090
  • Packaging10mg
  • Price$286
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3307
  • Product descriptionCHIR-090
  • Packaging200mg
  • Price$2299
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2000
  • Product descriptionCHIR090 99%
  • Packaging25mg
  • Price$555.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22256
  • Product descriptionCHIR090 ≥98%
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22256
  • Product descriptionCHIR090 ≥98%
  • Packaging5mg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22256
  • Product descriptionCHIR090 ≥98%
  • Packaging10mg
  • Price$275
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM163910
  • Product descriptionN-((2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl)-4-((4-(morpholinomethyl)phenyl)ethynyl)benzamide 98%
  • Packaging10mg
  • Price$234
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM163910
  • Product descriptionN-((2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl)-4-((4-(morpholinomethyl)phenyl)ethynyl)benzamide 98%
  • Packaging50mg
  • Price$853
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0973
  • Product descriptionCHIR-090 99.20%
  • Packaging5mg
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0973
  • Product descriptionCHIR-090 99.20%
  • Packaging10mg
  • Price$312
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0973
  • Product descriptionCHIR-090 99.20%
  • Packaging50mg
  • Price$1140
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000951
  • Product descriptionCHIR-090 98+%
  • Packaging50mg
  • Price$912
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000951
  • Product descriptionCHIR-090 98+%
  • Packaging10mg
  • Price$250
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS111888 CHIR-090 98% 5mg $204 2021-12-16 Buy
Activate Scientific AS111888 CHIR-090 98% 25mg $535 2021-12-16 Buy
AK Scientific 3541AH N-[(1S,2R)-2-Hydroxy-1-[(hydroxyamino)carbonyl]propyl]-4-[[4-(4-morpholinylmethyl)phenyl]ethynyl]benzamide 5mg $227 2021-12-16 Buy
ApexBio Technology A3307 CHIR-090 10mg $286 2021-12-16 Buy
ApexBio Technology A3307 CHIR-090 200mg $2299 2021-12-16 Buy
Axon Medchem Axon2000 CHIR090 99% 25mg $555.5 2021-12-16 Buy
Cayman Chemical 22256 CHIR090 ≥98% 1mg $57 2024-03-01 Buy
Cayman Chemical 22256 CHIR090 ≥98% 5mg $166 2024-03-01 Buy
Cayman Chemical 22256 CHIR090 ≥98% 10mg $275 2024-03-01 Buy
Chemenu CM163910 N-((2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl)-4-((4-(morpholinomethyl)phenyl)ethynyl)benzamide 98% 10mg $234 2021-12-16 Buy
Chemenu CM163910 N-((2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl)-4-((4-(morpholinomethyl)phenyl)ethynyl)benzamide 98% 50mg $853 2021-12-16 Buy
ChemScene CS-0973 CHIR-090 99.20% 5mg $192 2021-12-16 Buy
ChemScene CS-0973 CHIR-090 99.20% 10mg $312 2021-12-16 Buy
ChemScene CS-0973 CHIR-090 99.20% 50mg $1140 2021-12-16 Buy
Crysdot CD31000951 CHIR-090 98+% 50mg $912 2021-12-16 Buy
Crysdot CD31000951 CHIR-090 98+% 10mg $250 2021-12-16 Buy
Next Last

Properties

Density :1.33±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥21.85 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :9.11±0.40(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P341 IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P310 Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

CHIR-090 is the first reported compound that in fact kills both E. coli and Pseudomonas aeruginosa in bacterial disk diffusion assays (Liang et al. 2011). Nonetheless, CHIR-090 was about 600-fold less effective against LpxC orthologs from the Rhizobiaceae family than against E. coli LpxC. In this way, studies have shown that the removal of morpholine ring, based on a chemical scaffold of reduced radius, was able to increase affinity by 20-fold for LpxC enzymes from the Rhizobiaceae family of bacteria and enhance the antibiotic activity against E. coli and P. aeruginosa by 2–4 fold over CHIR-090.

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Suppliers and manufacturers

career henan chemical co
N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]benzamide
$1.00 /1KG
N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]benzamide CAS:728865-23-4
TargetMol Chemicals Inc.
CHIR-090
$40.00 /1mg
CHIR-090 CAS:728865-23-4
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Dayang Chem (Hangzhou) Co.,Ltd.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
PT CHEM GROUP LIMITED
ShenZhen Trendseen Biological Technology Co.,Ltd.