Welcome to chemicalbook!
China English Japan Germany
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structured search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook My chemicalbook

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> CHIR 98014

CHIR 98014

CHIR 98014 price.
  • $55 - $1647
  • Product name: CHIR 98014
  • CAS: 556813-39-9
  • MF: C20H17Cl2N9O2
  • MW: 486.31
  • EINECS:
  • MDL Number:MFCD24369684
  • Synonyms:CHIR 98014;N6-[2-[[4-(2,4-Dichlorophenyl)-5-(1H-iMidazol-2-yl)-2-pyriMidinyl]aMino]ethyl]-3-nitro- 2,6-pyridinediaMine;N2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,;N2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine;N2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine;CHIR 98014;CHIR98014;CHIR-98014;CT98014;CT98014;CS-71
Price29 Properties Safety Information Description
29 prices
Selected condition：
Brand
  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • CSNpharm
  • Matrix Scientific
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 5
  • 2mg
  • 1mg
  • 10mg
  • 25
  • 25mg
  • 50mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number8126AB
  • Product descriptionN2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine
  • Packaging2mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number556813399
  • Product descriptionN2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine
  • Packaging10mg
  • Price$230.05
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number556813399
  • Product descriptionN2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine
  • Packaging50mg
  • Price$763.56
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA179486
  • Product descriptionCHIR-98024 95+%
  • Packaging2mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA179486
  • Product descriptionCHIR-98024 95+%
  • Packaging5mg
  • Price$123
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA179486
  • Product descriptionCHIR-98024 95+%
  • Packaging10mg
  • Price$209
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA179486
  • Product descriptionCHIR-98024 95+%
  • Packaging25mg
  • Price$354
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA179486
  • Product descriptionCHIR-98024 95+%
  • Packaging50mg
  • Price$461
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0002524
  • Product descriptionN-6-[2-[[4-(2,4-DICHLOROPHENYL)-5-(1H-IMIDAZOL-2-YL)-2-PYRIMIDINYL]AMINO]ETHYL]-3-NITRO-2,6-PYRIDINEDIAMINE 95.00%
  • Packaging5MG
  • Price$451.34
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC19922
  • Product descriptionCHIR 98014
  • Packaging10mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC19922
  • Product descriptionCHIR 98014
  • Packaging50mg
  • Price$437.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15578
  • Product descriptionCHIR98014 ≥98%
  • Packaging1mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15578
  • Product descriptionCHIR98014 ≥98%
  • Packaging5mg
  • Price$146
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15578
  • Product descriptionCHIR98014 ≥98%
  • Packaging10mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15578
  • Product descriptionCHIR98014 ≥98%
  • Packaging25mg
  • Price$553
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM166538
  • Product descriptionN2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine 95%
  • Packaging10mg
  • Price$201
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8126AB N2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine 2mg $116 2021-12-16 Buy
Alichem 556813399 N2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine 10mg $230.05 2021-12-16 Buy
Alichem 556813399 N2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine 50mg $763.56 2021-12-16 Buy
Ambeed A179486 CHIR-98024 95+% 2mg $69 2021-12-16 Buy
Ambeed A179486 CHIR-98024 95+% 5mg $123 2021-12-16 Buy
Ambeed A179486 CHIR-98024 95+% 10mg $209 2021-12-16 Buy
Ambeed A179486 CHIR-98024 95+% 25mg $354 2021-12-16 Buy
Ambeed A179486 CHIR-98024 95+% 50mg $461 2021-12-16 Buy
American Custom Chemicals Corporation KIN0002524 N-6-[2-[[4-(2,4-DICHLOROPHENYL)-5-(1H-IMIDAZOL-2-YL)-2-PYRIMIDINYL]AMINO]ETHYL]-3-NITRO-2,6-PYRIDINEDIAMINE 95.00% 5MG $451.34 2021-12-16 Buy
Biosynth Carbosynth FC19922 CHIR 98014 10mg $125 2021-12-16 Buy
Biosynth Carbosynth FC19922 CHIR 98014 50mg $437.5 2021-12-16 Buy
Cayman Chemical 15578 CHIR98014 ≥98% 1mg $65 2021-12-16 Buy
Cayman Chemical 15578 CHIR98014 ≥98% 5mg $146 2021-12-16 Buy
Cayman Chemical 15578 CHIR98014 ≥98% 10mg $260 2021-12-16 Buy
Cayman Chemical 15578 CHIR98014 ≥98% 25mg $553 2021-12-16 Buy
Chemenu CM166538 N2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine 95% 10mg $201 2021-12-16 Buy
Next Last

Properties

Melting point :192-196°C
Boiling point :839.0±75.0 °C(Predicted)
Density :1.573±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: slightly soluble,Ethanol: slightly soluble
form :A solid
pka :10.98±0.10(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P363 Wash contaminated clothing before reuse.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.

Description

The two isoforms of glycogen synthase kinase 3, GSK3α and GSK3β, constitutively phosphorylates and inactivates glycogen synthase, preventing glycogen synthesis. They also phosphorylate proteins that are relevant to Alzheimer’s disease and osteogenesis. CHIR98014 is a reversible, cell-permeable inhibitor of GSK3α and GSK3β (IC50 = 0.65 and 0.58 nM, respectively). It is inactive against a series of other serine/threonine or tyrosine kinases. Through its effects on GSK3, CHIR98014 stimulates glycogen synthase in cells (EC50 = 106 nM), potentiates insulin-dependent glucose transport in isolated muscle strips, and improves glucose disposal in diabetic animals. CHIR98014 also reduces tau phosphorylation in rat brains and supports Wnt signaling during osteogenesis.

Suppliers and manufacturers

Nanjing Doge Biomedical Technology Co., Ltd
Coresyn Pharmatech Co., Ltd.
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
LEAPCHEM CO., LTD.
Aladdin Scientific
Aladdin Scientific
Amadis Chemical Company Limited J & K SCIENTIFIC LTD.