CHLAMYDOCIN
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- $396 - $1320
- Product name: CHLAMYDOCIN
- CAS: 53342-16-8
- MF: C28H38N4O6
- MW: 526.63
- EINECS:
- MDL Number:MFCD31380760
- Synonyms:Cyclo[2-methylalanyl-L-phenylalanyl-D-prolyl-(aS,2S)-a-amino-h-oxo-2-oxiraneoctanoyl];CHLAMYDOCIN;2-Methylcyclo[Ala-L-Phe-D-Pro-6-[(S)-2-oxo-2-oxiranylethyl]-L-Nle-];Antibiotic SL-3440;SL-3440;Cyclo[2-methylalanyl-L-phenylalanyl-D-prolyl-(αS,2S)-α-amino-η-oxo-2-oxiraneoctanoyl]
2 prices
Selected condition：
Brand
- Cayman Chemical
- TRC
Package
- 1mg
- 10mg
- ManufacturerCayman Chemical
- Product number28468
- Product descriptionChlamydocin
- Packaging1mg
- Price$396
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberC292200
- Product descriptionChlamydocin
- Packaging10mg
- Price$1320
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 28468 | Chlamydocin | 1mg | $396 | 2024-03-01 | Buy |
| TRC | C292200 | Chlamydocin | 10mg | $1320 | 2021-12-16 | Buy |
Properties
Boiling point :861.8±65.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble; Ethanol: soluble; Methanol: soluble
form :A solid
pka :13.36±0.70(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble; Ethanol: soluble; Methanol: soluble
form :A solid
pka :13.36±0.70(Predicted)
Safety Information
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Description
Chlamydocin is a histone deacetylase (HDAC) inhibitor that was originally isolated from D. chlamydosporia and has anticancer properties. It is selective for HDAC1 over HDAC6 (IC50 = 0.15 and 1,100 nM, respectively). Chlamydocin increases acetylation of histone H3 and histone H4 in A2780 cells when used at concentrations ranging from 1 to 1,000 nM. It inhibits growth of A2780, Malme-3M, MCF-7, HT-29, and HeLa cancer cells (IC50s = 0.36, 45, 5.3, 4.3, and 14 nM, respectively). Chlamydocin increases lifespan by 10% in a P185 mouse allograft model when administered at doses ranging from 20 to 160 mg/kg.More related product prices
CyclenRelated product price
- CHLAMYDOCIN
$396-1320 - Cyclen
$5-2055.9
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