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ChemicalBook >> CAS DataBase List >> CHR-6494

CHR-6494

CHR-6494 price.
  • $32 - $917
  • Product name: CHR-6494
  • CAS: 1333377-65-3
  • MF: C16H16N6
  • MW: 292.34
  • EINECS:
  • MDL Number:MFCD22666352
  • Synonyms:3-(1H-indazol-5-yl)-N-propyliMidazo[1,2-b]pyridazin-6-aMine;CHR-6494 3-(1H-indazol-5-yl)-N-propyliMidazo[1,2-b]pyridazin-6-aMine;3-(1H-Indazol-5-yl)-N-propyl-imidazo[1,2-b]pyridazin-6-amine trifluoroacetate salt;3-(1H-Indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine trifluoroacetate salt;CHR 6494 trifluoroacetate salt;CHR-6494 trifluoroacetate salt;Haspin Kinase Inhibitor, CHR-6494 ;CHR-6494
Price24 Properties Safety Information Description
24 prices
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Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product numberSYN5064
  • Product descriptionCHR-6494TFASalt
  • Packaging10mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5064
  • Product descriptionCHR-6494TFASalt
  • Packaging50mg
  • Price$540
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3309
  • Product descriptionCHR-6494
  • Packaging5mg
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3309
  • Product descriptionCHR-6494
  • Packaging10mg
  • Price$182
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3309
  • Product descriptionCHR-6494
  • Packaging50mg
  • Price$542
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3309
  • Product descriptionCHR-6494
  • Packaging100mg
  • Price$917
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11478
  • Product descriptionCHR-6494 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11478
  • Product descriptionCHR-6494 ≥98%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11478
  • Product descriptionCHR-6494 ≥98%
  • Packaging10mg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0994
  • Product descriptionCHR-6494 98.70%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0994
  • Product descriptionCHR-6494 98.70%
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0994
  • Product descriptionCHR-6494 98.70%
  • Packaging50mg
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0994
  • Product descriptionCHR-6494 98.70%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003853
  • Product descriptionCHR-6494 98+%
  • Packaging5mg
  • Price$43
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003853
  • Product descriptionCHR-6494 98+%
  • Packaging10mg
  • Price$81
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003853
  • Product descriptionCHR-6494 98+%
  • Packaging50mg
  • Price$241
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5064 CHR-6494TFASalt 10mg $145 2021-12-16 Buy
AK Scientific SYN5064 CHR-6494TFASalt 50mg $540 2021-12-16 Buy
ApexBio Technology A3309 CHR-6494 5mg $97 2021-12-16 Buy
ApexBio Technology A3309 CHR-6494 10mg $182 2021-12-16 Buy
ApexBio Technology A3309 CHR-6494 50mg $542 2021-12-16 Buy
ApexBio Technology A3309 CHR-6494 100mg $917 2021-12-16 Buy
Cayman Chemical 11478 CHR-6494 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 11478 CHR-6494 ≥98% 5mg $93 2024-03-01 Buy
Cayman Chemical 11478 CHR-6494 ≥98% 10mg $166 2024-03-01 Buy
ChemScene CS-0994 CHR-6494 98.70% 5mg $60 2021-12-16 Buy
ChemScene CS-0994 CHR-6494 98.70% 10mg $90 2021-12-16 Buy
ChemScene CS-0994 CHR-6494 98.70% 50mg $320 2021-12-16 Buy
ChemScene CS-0994 CHR-6494 98.70% 100mg $550 2021-12-16 Buy
Crysdot CD31003853 CHR-6494 98+% 5mg $43 2021-12-16 Buy
Crysdot CD31003853 CHR-6494 98+% 10mg $81 2021-12-16 Buy
Crysdot CD31003853 CHR-6494 98+% 50mg $241 2021-12-16 Buy
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Properties

Density :1.39±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :13.24±0.40(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

CHR-6494 is a haspin protein kinase inhibitor (IC50 = 2 nM) selective over 27 other protein kinases, including Aurora B kinase (IC50 > 1 μM). Haspin is a kinase necessary for mitosis that selectively phosphorylates histone 3 at the threonine 3 residue (H3T3ph). CHR-6494 decreases phosphorylation of H3T3 and arrests the cell cycle in the G2/M phase, which leads to apoptosis. It showed promising results in a xenograft tumor model.

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