CID 2745687
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- $70 - $1025
- Product name: CID 2745687
- CAS: 264233-05-8
- MF: C17H19F2N5O2S
- MW: 395.43
- EINECS:
- MDL Number:MFCD00111058
- Synonyms:CID 2745687;Methyl 1-(2,4-Difluoro-phenyl)-5-((4-tert-butyl-thioseMicarbazono)Methyl)-1H-pyrazole-4-carboxylate;methyl 5-[(E)-(tert-butylcarbamothioylhydrazono)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylate;1H-Pyrazole-4-carboxylic acid, 1-(2,4-difluorophenyl)-5-[[2-[[(1,1-dimethylethyl)amino]thioxomethyl]hydrazinylidene]methyl]-, methyl ester;GPCR,CID-2745687,CID2745687,G Protein-coupled Receptors,inhibit,Inhibitor,CID 2745687,Arrestin,GPR35 antagonist
17 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Medical Isotopes, Inc.
- Tocris
- TRC
- Usbiological
Package
- 50
- 5mg
- 10mg
- 25mg
- 10
- 50mg
- ManufacturerAK Scientific
- Product number0465CR
- Product descriptionMethyl5-[(E)-(tert-butylcarbamothioylhydrazinylidene)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylate
- Packaging5mg
- Price$201
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number0465CR
- Product descriptionMethyl5-[(E)-(tert-butylcarbamothioylhydrazinylidene)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylate
- Packaging25mg
- Price$455
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number0465CR
- Product descriptionMethyl5-[(E)-(tert-butylcarbamothioylhydrazinylidene)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylate
- Packaging50mg
- Price$758
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010249
- Product description1-(2,4-DIFLUOROPHENYL)-5-[[2-[[(1,1-DIMETHYLEHYL)AMINO]THIOXOMETHYL]HYDRAZINYLIDENE]METHYL]-1H-PYRAZOLE-4-CARBOXYLIC ACID 95.00%
- Packaging5MG
- Price$206.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7635
- Product descriptionCID2745687
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7635
- Product descriptionCID2745687
- Packaging10mg
- Price$158
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7635
- Product descriptionCID2745687
- Packaging25mg
- Price$365
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7635
- Product descriptionCID2745687
- Packaging50mg
- Price$677
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number12046
- Product descriptionCID-2745687 ≥95%
- Packaging5mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number12046
- Product descriptionCID-2745687 ≥95%
- Packaging10mg
- Price$139
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number12046
- Product descriptionCID-2745687 ≥95%
- Packaging25mg
- Price$321
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number12046
- Product descriptionCID-2745687 ≥95%
- Packaging50mg
- Price$593
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number52237
- Product descriptionMethyl1-(2,4-Difluoro-phenyl)-5-((4-tert-butyl-thiosemicarbazono)methyl)-1H-pyrazole-4-carboxylate
- Packaging50mg
- Price$1025
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number4293
- Product descriptionCID2745687 ≥98%(HPLC)
- Packaging10
- Price$203
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number4293
- Product descriptionCID2745687 ≥98%(HPLC)
- Packaging50
- Price$824
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberM301800
- Product descriptionMethyl1-(2,4-Difluoro-phenyl)-5-((4-tert-butyl-thiosemicarbazono)methyl)-1H-pyrazole-4-carboxylate
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 0465CR | Methyl5-[(E)-(tert-butylcarbamothioylhydrazinylidene)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylate | 5mg | $201 | 2021-12-16 | Buy |
| AK Scientific | 0465CR | Methyl5-[(E)-(tert-butylcarbamothioylhydrazinylidene)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylate | 25mg | $455 | 2021-12-16 | Buy |
| AK Scientific | 0465CR | Methyl5-[(E)-(tert-butylcarbamothioylhydrazinylidene)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylate | 50mg | $758 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010249 | 1-(2,4-DIFLUOROPHENYL)-5-[[2-[[(1,1-DIMETHYLEHYL)AMINO]THIOXOMETHYL]HYDRAZINYLIDENE]METHYL]-1H-PYRAZOLE-4-CARBOXYLIC ACID 95.00% | 5MG | $206.8 | 2021-12-16 | Buy |
| ApexBio Technology | B7635 | CID2745687 | 5mg | $104 | 2021-12-16 | Buy |
| ApexBio Technology | B7635 | CID2745687 | 10mg | $158 | 2021-12-16 | Buy |
| ApexBio Technology | B7635 | CID2745687 | 25mg | $365 | 2021-12-16 | Buy |
| ApexBio Technology | B7635 | CID2745687 | 50mg | $677 | 2021-12-16 | Buy |
| Cayman Chemical | 12046 | CID-2745687 ≥95% | 5mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 12046 | CID-2745687 ≥95% | 10mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 12046 | CID-2745687 ≥95% | 25mg | $321 | 2024-03-01 | Buy |
| Cayman Chemical | 12046 | CID-2745687 ≥95% | 50mg | $593 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | 52237 | Methyl1-(2,4-Difluoro-phenyl)-5-((4-tert-butyl-thiosemicarbazono)methyl)-1H-pyrazole-4-carboxylate | 50mg | $1025 | 2021-12-16 | Buy |
| Tocris | 4293 | CID2745687 ≥98%(HPLC) | 10 | $203 | 2021-12-16 | Buy |
| Tocris | 4293 | CID2745687 ≥98%(HPLC) | 50 | $824 | 2021-12-16 | Buy |
| TRC | M301800 | Methyl1-(2,4-Difluoro-phenyl)-5-((4-tert-butyl-thiosemicarbazono)methyl)-1H-pyrazole-4-carboxylate | 5mg | $70 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :crystalline solid
color :Off-white to light yellow
solubility :Soluble in DMSO
form :crystalline solid
color :Off-white to light yellow
Safety Information
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Description
GPR35 is a G protein-coupled receptor that is activated by kynurenic acid and 2-acyl lysophosphatidic acids (e.g., 2-oleoyl lysophosphatidic acid). It is expressed predominantly on immune cells, the brain, and in the gastrointestinal tract. GPR35 is overexpressed in gastric cancer cells. CID-2745687 is a reversible, competitive antagonist of GPR35, blocking activation by the synthetic agonist pamoic acid with a Ki value of 12.8 nM. It less potently blocks activation of GPR35 by zaprinast (IC50 = 160 nM). It shows ~57-fold selectivity for GPR35 over the related receptor GPR55 (IC50 = 9.08 μM).Suppliers and manufacturers
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd
J & K SCIENTIFIC LTD.
BOC Sciences
Shanghai TaoSu Biochemical Technology Co., Ltd.
Shanghai Lollane Biological Technology Co.,Ltd.
EMMX Biotechnology LLC