COMBRETASTATIN A-4
- $24 - $2880
- Product name: COMBRETASTATIN A-4
- CAS: 117048-59-6
- MF: C18H20O5
- MW: 316.35
- EINECS:
- MDL Number:MFCD03453309
- Synonyms:(Z)-2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenol,3,4,5-Trimethoxy-3hydroxy-4methoxy-(Z)-stilbene,CS-A4;Combrestatin A4( 2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol );(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol ,98%;2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol;3-[(Z)-2-(3,4,5-Trimethoxyphenyl)ethenyl]-6-methoxyphenol;5-[(Z)-2-(3,4,5-Trimethoxyphenyl)ethenyl]-2-methoxyphenol;Combretastatin A4;(Z)-CombretastatinA4
44 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 10μg
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- ManufacturerAdipogen Life Sciences
- Product numberCDX-C0706-M010
- Product descriptionCombretastatin A4 ≥98%(HPLC)
- Packaging10mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-C0706-M050
- Product descriptionCombretastatin A4 ≥98%(HPLC)
- Packaging50mg
- Price$429
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0443
- Product descriptionCombretastatin A4
- Packaging1g
- Price$593
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA300403
- Product description(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98%
- Packaging5mg
- Price$24
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA300403
- Product description(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98%
- Packaging10mg
- Price$31
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA300403
- Product description(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98%
- Packaging25mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA300403
- Product description(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98%
- Packaging100mg
- Price$67
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA300403
- Product description(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98%
- Packaging250mg
- Price$122
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA300403
- Product description(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98%
- Packaging1g
- Price$310
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA300403
- Product description(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98%
- Packaging5g
- Price$1056
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0000489
- Product descriptionCOMBRETASTATIN A4 95.00%
- Packaging1G
- Price$660.45
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6764
- Product descriptionCombretastatin A4
- Packaging5mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6764
- Product descriptionCombretastatin A4
- Packaging10mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6764
- Product descriptionCombretastatin A4
- Packaging25mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594615
- Product descriptionCombretastatin A4
- Packaging20mg
- Price$187
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594615
- Product descriptionCombretastatin A4
- Packaging100mg
- Price$372.3
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | CDX-C0706-M010 | Combretastatin A4 ≥98%(HPLC) | 10mg | $100 | 2021-12-16 | Buy |
Adipogen Life Sciences | CDX-C0706-M050 | Combretastatin A4 ≥98%(HPLC) | 50mg | $429 | 2021-12-16 | Buy |
AK Scientific | Y0443 | Combretastatin A4 | 1g | $593 | 2021-12-16 | Buy |
Ambeed | A300403 | (Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98% | 5mg | $24 | 2021-12-16 | Buy |
Ambeed | A300403 | (Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98% | 10mg | $31 | 2021-12-16 | Buy |
Ambeed | A300403 | (Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98% | 25mg | $40 | 2021-12-16 | Buy |
Ambeed | A300403 | (Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98% | 100mg | $67 | 2021-12-16 | Buy |
Ambeed | A300403 | (Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98% | 250mg | $122 | 2021-12-16 | Buy |
Ambeed | A300403 | (Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98% | 1g | $310 | 2021-12-16 | Buy |
Ambeed | A300403 | (Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol 98% | 5g | $1056 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0000489 | COMBRETASTATIN A4 95.00% | 1G | $660.45 | 2021-12-16 | Buy |
ApexBio Technology | B6764 | Combretastatin A4 | 5mg | $75 | 2021-12-16 | Buy |
ApexBio Technology | B6764 | Combretastatin A4 | 10mg | $120 | 2021-12-16 | Buy |
ApexBio Technology | B6764 | Combretastatin A4 | 25mg | $270 | 2021-12-16 | Buy |
Biorbyt Ltd | orb594615 | Combretastatin A4 | 20mg | $187 | 2021-12-16 | Buy |
Biorbyt Ltd | orb594615 | Combretastatin A4 | 100mg | $372.3 | 2021-12-16 | Buy |
Properties
Melting point :84.5-85.5°C
Boiling point :490.3±45.0 °C(Predicted)
Density :1.184±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >10mg/mL
form :powder
pka :9.65±0.10(Predicted)
color :off-white
Merck :14,2494
Boiling point :490.3±45.0 °C(Predicted)
Density :1.184±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >10mg/mL
form :powder
pka :9.65±0.10(Predicted)
color :off-white
Merck :14,2494
Safety Information
Symbol(GHS): | |||||||||||||||
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Signal word: | Danger | ||||||||||||||
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Precautionary statements: |
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Description
Combrestatin A4 (CA4) is a potent inhibitor of tubulin polymerization and displays strong inhibitory activity on tumor cell growth. CA4 was shown to impede tumor growth in several cell lines including IMR32 (neuroblastoma), Hs746T (gastric carcinoma), CFPAC-1 (pancreatic carcinoma), and MCF-7 (breast cancer) with IC50 values of 2.16, 5.20, 3.46, and 18.47 nM, respectively. CA4 inhibits tubulin polymerization with an IC50 value of 2.2 μM. Combrestatin A4 is an inhibitor of β Tubulin.Related product price
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