CP 640186
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- $44 - $650
- Product name: CP 640186
- CAS: 591778-68-6
- MF: C30H35N3O3
- MW: 485.62
- EINECS:
- MDL Number:MFCD25976696
- Synonyms:CP 640186 (R)-ANTHRACEN-9-YL(3-(MORPHOLINE-4-CARBONYL)-1,4'-BIPIPERIDIN-1'-YL)METHANONE.HCL;(Anthracen-9-yl)[(3R)-3-[(morpholin-4-yl)carbonyl][1,4']bipiperidinyl-1'-yl]methanone;(R)-Anthracen-9-yl(3-(morpholine-4-carbonyl)-[1,4'-bipiperidin]-1'-yl)methanone;[(3R)-1-[1-(anthracene-9-carbonyl)piperidin-4-yl]piperidin-3-yl]-morpholin-4-ylmethanone;CP 640186;(R)-ANTHRACEN-9-YL(3-(MORPHOLINE-4-CARBONYL)-1,4'-BIPIPERIDIN-1'-YL)METHANONE.HCL;(R)-anthracen-9-yl(3-(morpholine-4-carbonyl)-[1,4'-bipiperidin]-1'-yl)metha none CP640186;CS-1316
9 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- Crysdot
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product number3078CC
- Product description(3R)-1'-(9-Anthrylcarbonyl)-3-(morpholin-4-ylcarbonyl)-1,4'-bipiperidine
- Packaging1mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17691
- Product descriptionCP 640,186 ≥95%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17691
- Product descriptionCP 640,186 ≥95%
- Packaging5mg
- Price$151
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17691
- Product descriptionCP 640,186 ≥95%
- Packaging10mg
- Price$257
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17691
- Product descriptionCP 640,186 ≥95%
- Packaging25mg
- Price$533
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31001371
- Product descriptionCP-640186 98+%
- Packaging5mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001371
- Product descriptionCP-640186 98+%
- Packaging10mg
- Price$137
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001371
- Product descriptionCP-640186 98+%
- Packaging50mg
- Price$539
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7975
- Product descriptionCP640186 >98%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3078CC | (3R)-1'-(9-Anthrylcarbonyl)-3-(morpholin-4-ylcarbonyl)-1,4'-bipiperidine | 1mg | $147 | 2021-12-16 | Buy |
| Cayman Chemical | 17691 | CP 640,186 ≥95% | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 17691 | CP 640,186 ≥95% | 5mg | $151 | 2024-03-01 | Buy |
| Cayman Chemical | 17691 | CP 640,186 ≥95% | 10mg | $257 | 2024-03-01 | Buy |
| Cayman Chemical | 17691 | CP 640,186 ≥95% | 25mg | $533 | 2024-03-01 | Buy |
| Crysdot | CD31001371 | CP-640186 98+% | 5mg | $84 | 2021-12-16 | Buy |
| Crysdot | CD31001371 | CP-640186 98+% | 10mg | $137 | 2021-12-16 | Buy |
| Crysdot | CD31001371 | CP-640186 98+% | 50mg | $539 | 2021-12-16 | Buy |
| DC Chemicals | DC7975 | CP640186 >98% | 100mg | $650 | 2021-12-16 | Buy |
Properties
Boiling point :721.1±60.0 °C(Predicted)
Density :1.245±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form :A crystalline solid
pka :8.07±0.40(Predicted)
color :Light yellow to light brown
Density :1.245±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form :A crystalline solid
pka :8.07±0.40(Predicted)
color :Light yellow to light brown
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA, a precursor for fatty acids. CP 640,186 is an isozyme-nonselective ACC inhibitor with IC50 values of 53 and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2, respectively. It has been shown to lower malonyl-CoA levels and to inhibit hepatic fatty acid and triglyceride synthesis both in vitro and in vivo. CP 640,186 can also stimulate muscle fatty acid oxidation (EC50 = 1.3 μM in rat epitrochlearis muscle strips) and lower whole body respiratory quotient in rats (ED50 = ~30 mg/kg).More related product prices
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