CPI-1189
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- $32 - $1600
- Product name: CPI-1189
- CAS: 183619-38-7
- MF: C13H18N2O2
- MW: 234.29
- EINECS:-0
- MDL Number:MFCD00774476
- Synonyms:CPI-1189;4-Acetamido-N-(tert-butyl)benzamide;CPI-1189;CPI 1189;REN1189;REN 1189;REN 1189;REN1189;CPI1189(REN-1189);Benzamide, 4-(acetylamino)-N-(1,1-dimethylethyl)-;REN-1189(CPI-1189)
9 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- DC Chemicals
Package
- 5MG
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number0530CB
- Product description4-Acetamido-N-tert-butylbenzamide
- Packaging100mg
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM1025663
- Product descriptionN-TERT-BUTYL-4-ACETAMIDOBENZAMIDE 95.00%
- Packaging5MG
- Price$504.19
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29187
- Product descriptionCPI-1189
- Packaging250mg
- Price$199
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29187
- Product descriptionCPI-1189
- Packaging100mg
- Price$98
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29187
- Product descriptionCPI-1189
- Packaging50mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29187
- Product descriptionCPI-1189
- Packaging25mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC9736
- Product descriptionCPI1189(REN-1189) >98%
- Packaging100mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9736
- Product descriptionCPI1189(REN-1189) >98%
- Packaging250mg
- Price$800
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9736
- Product descriptionCPI1189(REN-1189) >98%
- Packaging1g
- Price$1600
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 0530CB | 4-Acetamido-N-tert-butylbenzamide | 100mg | $208 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM1025663 | N-TERT-BUTYL-4-ACETAMIDOBENZAMIDE 95.00% | 5MG | $504.19 | 2021-12-16 | Buy |
| Cayman Chemical | 29187 | CPI-1189 | 250mg | $199 | 2024-03-01 | Buy |
| Cayman Chemical | 29187 | CPI-1189 | 100mg | $98 | 2024-03-01 | Buy |
| Cayman Chemical | 29187 | CPI-1189 | 50mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 29187 | CPI-1189 | 25mg | $32 | 2024-03-01 | Buy |
| DC Chemicals | DC9736 | CPI1189(REN-1189) >98% | 100mg | $450 | 2021-12-16 | Buy |
| DC Chemicals | DC9736 | CPI1189(REN-1189) >98% | 250mg | $800 | 2021-12-16 | Buy |
| DC Chemicals | DC9736 | CPI1189(REN-1189) >98% | 1g | $1600 | 2021-12-16 | Buy |
Properties
Melting point :119-121 °C
Boiling point :458.3±28.0 °C(Predicted)
Density :1.102±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥23.4 mg/mL in DMSO; insoluble in H2O; ≥18.4 mg/mL in EtOH with ultrasonic
form :solid
pka :14.65±0.70(Predicted)
color :White to off-white
Boiling point :458.3±28.0 °C(Predicted)
Density :1.102±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥23.4 mg/mL in DMSO; insoluble in H2O; ≥18.4 mg/mL in EtOH with ultrasonic
form :solid
pka :14.65±0.70(Predicted)
color :White to off-white
Safety Information
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Description
CPI-1189 is a benzamide with neuroprotective and anti-inflammatory activities. It inhibits phosphorylation of p38 MAPK in IL-1β-stimulated primary rat astrocytes by 70 to 80% when used at concentrations ranging from 10 to 300 nM. CPI-1189 (20 mg/kg per day) reduces TNF-α-induced apoptosis in the corpus callosum and septum, but not in the neocortex or basal ganglia, as well as reduces TNF-α-induced decreases in GFAP levels in isolated rat brain slices. It decreases the latency to find the platform in the Morris water maze, indicating reversal of memory deficits, induced by TNF-α in a rat model of AIDS dementia when administered at a dose of 20 mg/kg per day. CPI-1189 (30 mg/kg per day) reduces crypt loss and decreases the number of ulcers and inflammatory cells in colonic lesions in mouse models of colitis induced by TNBS or dextran sulfate sodium (DSS; ).Related product price
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