Cefotaxime
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- $50 - $1666
- Product name: Cefotaxime
- CAS: 63527-52-6
- MF: C16H17N5O7S2
- MW: 455.47
- EINECS:264-299-1
- MDL Number:MFCD00864971
- Synonyms:Cefotaxime;Cefotaxima acid;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-;Cefabol;Cephotaxime;(((2-amino- 4-thiazolyl)methoxyimino)acetyl)amino)-8-oxo-, (6r-(6alpha,7beta(z) 3-[(Acetyloxy)methyl]-7-[[(2-amino-4-thiazoly)(methoxyimino)acethyl]amino]-8-oxo-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylic acid(sodium salt);(6R)-3-(Acetoxymethyl)-7α-[[(2-amino-4-thiazolyl)[(Z)-methoxyimino]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(6R,7R)-7α-[2-(2-Amino-4-thiazolyl)-2-[(Z)-methoxyimino]acetylamino]-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
11 prices
Selected condition:
Brand
- AHH
- AK Scientific
- ChemScene
- Matrix Scientific
- Sigma-Aldrich
- TRC
Package
- y0000420
- 25mg
- 100mg
- 250mg
- 500mg
- 1g
- 2.5g
- 5g
- ManufacturerAHH
- Product numberMT-49079
- Product descriptionCefotaxime 98%
- Packaging5g
- Price$310
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ90010
- Product descriptionCefotaxime
- Packaging1g
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberF941
- Product descriptionCefotaxime
- Packaging25mg
- Price$98.6
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ90010
- Product descriptionCefotaxime
- Packaging5g
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0013515
- Product descriptionCefotaxime 99.55%
- Packaging100mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0013515
- Product descriptionCefotaxime 99.55%
- Packaging250mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0013515
- Product descriptionCefotaxime 99.55%
- Packaging500mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number145093
- Product description(6R,7R)-3-(Acetoxymethyl)-7-((E)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 95%
- Packaging1g
- Price$1110
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number145093
- Product description(6R,7R)-3-(Acetoxymethyl)-7-((E)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 95%
- Packaging5g
- Price$1666
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberY0000420
- Product descriptionCefotaxime acid European Pharmacopoeia (EP) Reference Standard
- Packagingy0000420
- Price$220
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberC242958
- Product descriptionCefotaxime
- Packaging2.5g
- Price$225
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AHH | MT-49079 | Cefotaxime 98% | 5g | $310 | 2021-12-16 | Buy |
AK Scientific | J90010 | Cefotaxime | 1g | $60 | 2021-12-16 | Buy |
AK Scientific | F941 | Cefotaxime | 25mg | $98.6 | 2021-12-16 | Buy |
AK Scientific | J90010 | Cefotaxime | 5g | $150 | 2021-12-16 | Buy |
ChemScene | CS-0013515 | Cefotaxime 99.55% | 100mg | $50 | 2021-12-16 | Buy |
ChemScene | CS-0013515 | Cefotaxime 99.55% | 250mg | $100 | 2021-12-16 | Buy |
ChemScene | CS-0013515 | Cefotaxime 99.55% | 500mg | $135 | 2021-12-16 | Buy |
Matrix Scientific | 145093 | (6R,7R)-3-(Acetoxymethyl)-7-((E)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 95% | 1g | $1110 | 2021-12-16 | Buy |
Matrix Scientific | 145093 | (6R,7R)-3-(Acetoxymethyl)-7-((E)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 95% | 5g | $1666 | 2021-12-16 | Buy |
Sigma-Aldrich | Y0000420 | Cefotaxime acid European Pharmacopoeia (EP) Reference Standard | y0000420 | $220 | 2024-03-01 | Buy |
TRC | C242958 | Cefotaxime | 2.5g | $225 | 2021-12-16 | Buy |
Properties
Melting point :>158°C (dec.)
Density :1.80±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
pka :pKa 2.1 (H2O t=20.0 I<0.005 ) (Uncertain);3.4(H2O t=20.0 I<0.005 ) (Uncertain);10.9(H2O t=20.0 I<0.005 ) (Uncertain)
form :Solid
color :White to Off-White
Stability :Hygroscopic
LogP :1.2
CAS DataBase Reference :63527-52-6(CAS DataBase Reference)
EPA Substance Registry System :5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)- (63527-52-6)
Density :1.80±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
pka :pKa 2.1 (H2O t=20.0 I<0.005 ) (Uncertain);3.4(H2O t=20.0 I<0.005 ) (Uncertain);10.9(H2O t=20.0 I<0.005 ) (Uncertain)
form :Solid
color :White to Off-White
Stability :Hygroscopic
LogP :1.2
CAS DataBase Reference :63527-52-6(CAS DataBase Reference)
EPA Substance Registry System :5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)- (63527-52-6)
Safety Information
Symbol(GHS): |
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Signal word: | Danger | |||||||||||||||||||||
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Description
Like other third-generation cephalosporins, it has excellent anti-Gram-negative activity and is useful institutionally. It has a metabolically vulnerable acetoxy group attached to C-3 and loses approximately 90% of its activity when this is hydrolyzed. This metabolic feature also complicates the pharmacokinetic data, because both active forms are present and have different properties. Cefotaxime should be protected from heat and light and may color slightly without significant loss of potency. Like other third-generation cephalosporins, cefotaxime has less activity against staphylococci but has greater activity against Gram-negative organisms.Related product price
- Thioacetamide
$9-1270 - Cefotaxime sodium
$8-1750 - Acetamide
$13-950
Suppliers and manufacturers
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
HubeiwidelychemicaltechnologyCo.,Ltd
Chongqing Chemdad Co., Ltd
SIMAGCHEM CORP
Hefei TNJ Chemical Industry Co.,Ltd.
Shaanxi Dideu Medichem Co. Ltd