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ChemicalBook >> CAS DataBase List >> Cercosporamide

Cercosporamide

Cercosporamide price.
  • $216 - $1410
  • Product name: Cercosporamide
  • CAS: 131436-22-1
  • MF: C16H13NO7
  • MW: 331.28
  • EINECS:
  • MDL Number:
  • Synonyms:Cercosporamide;(R)-8-Acetyl-9,9a-dihydro-1,3,7-trihydroxy-9aβ-methyl-9-oxodibenzofuran-4-carboxamide;4-Dibenzofurancarboxamide;Cercosporamide from Cercosporidium henningsii;(9aS)-8-Acetyl-9,9a-dihydro-1,3,7-trihydroxy-9a-methyl-9-oxo-4-dibenzofurancaboxamide;(-)-CERCOSPORAMIDE;Cercosporamide ((-)-Cercosporamide);4-Dibenzofurancarboxamide, 8-acetyl-9,9a-dihydro-1,3,7-trihydroxy-9a-methyl-9-oxo-, (9aS)-
18 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Apolloscientific
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 100μg
  • 200ug
  • 500ug
  • 500μg
  • 1mg
  • 2.5mg
  • 5mg
  • 500U
  • ManufacturerAK Scientific
  • Product number4407BA
  • Product descriptionCercosporamide
  • Packaging2.5mg
  • Price$1309
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4511
  • Product descriptionCercosporamide
  • Packaging1mg
  • Price$1410
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0264
  • Product descriptionCercosporamide
  • Packaging1mg
  • Price$667
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546073
  • Product descriptionCercosporamide >98%
  • Packaging200ug
  • Price$226.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546073
  • Product descriptionCercosporamide >98%
  • Packaging1mg
  • Price$669.8
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15500
  • Product descriptionCercosporamide ≥95%
  • Packaging500μg
  • Price$242
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15500
  • Product descriptionCercosporamide ≥95%
  • Packaging2.5mg
  • Price$1087
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4664
  • Product descriptionCercosporamide >98.0%
  • Packaging500ug
  • Price$295
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4664
  • Product descriptionCercosporamide >98.0%
  • Packaging1mg
  • Price$570
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003910
  • Product descriptionCercosporamide 98+%
  • Packaging5mg
  • Price$581
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC23922
  • Product descriptionCercosporamide >98%
  • Packaging1mg
  • Price$216
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC23922
  • Product descriptionCercosporamide >98%
  • Packaging5mg
  • Price$664
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0172
  • Product descriptionCercosporamide from Cercosporidium henningsii ≥98% (HPLC)
  • Packaging500μg
  • Price$238.2
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number4500
  • Product descriptionCercosporamide ≥96%(HPLC)
  • Packaging500U
  • Price$233
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC270500
  • Product descriptionCercosporamide
  • Packaging100μg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number254920
  • Product descriptionCercosporamide
  • Packaging500ug
  • Price$489
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4407BA Cercosporamide 2.5mg $1309 2021-12-16 Buy
ApexBio Technology A4511 Cercosporamide 1mg $1410 2021-12-16 Buy
Apolloscientific BISN0264 Cercosporamide 1mg $667 2021-12-16 Buy
Biorbyt Ltd orb546073 Cercosporamide >98% 200ug $226.1 2021-12-16 Buy
Biorbyt Ltd orb546073 Cercosporamide >98% 1mg $669.8 2021-12-16 Buy
Cayman Chemical 15500 Cercosporamide ≥95% 500μg $242 2024-03-01 Buy
Cayman Chemical 15500 Cercosporamide ≥95% 2.5mg $1087 2024-03-01 Buy
ChemScene CS-4664 Cercosporamide >98.0% 500ug $295 2021-12-16 Buy
ChemScene CS-4664 Cercosporamide >98.0% 1mg $570 2021-12-16 Buy
Crysdot CD31003910 Cercosporamide 98+% 5mg $581 2021-12-16 Buy
DC Chemicals DC23922 Cercosporamide >98% 1mg $216 2021-12-16 Buy
DC Chemicals DC23922 Cercosporamide >98% 5mg $664 2021-12-16 Buy
Sigma-Aldrich SML0172 Cercosporamide from Cercosporidium henningsii ≥98% (HPLC) 500μg $238.2 2024-03-01 Buy
Tocris 4500 Cercosporamide ≥96%(HPLC) 500U $233 2021-12-16 Buy
TRC C270500 Cercosporamide 100μg $240 2021-12-16 Buy
Usbiological 254920 Cercosporamide 500ug $489 2021-12-16 Buy

Properties

Boiling point :582.5±50.0 °C(Predicted)
Density :1.70±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :chloroform: soluble1mg/mL
form :Powder
pka :11.89±0.70(Predicted)
color :White to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Cercosporamide is a natural antifungal phytotoxin isolated from the Cercosporidium fungus, which infects the leaves of cassava plants. Its antifungal effect results from its selective and potent inhibition of fungal PKC-like 1 kinases (Pkc1), which are central to cell wall integrity (IC50 = 25 nM for Candida Pkc1). Cercosporamide less effectively inhibits human PKC isoforms PKCα, β, and γ (IC50s = 1.02, 0.35, and 5.8 μM, respectively), an action linked to lowering of plasma glucose in hyperglycemic mice. However, it potently inhibits MAPK-interacting kinases Mnk1 and Mnk2 (IC50 = 115 and 11 nM, respectively), reducing protein translation in cancer cells. Cercosporamide is orally bioavailable.