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ChemicalBook >> CAS DataBase List >> Cilofexor

Cilofexor

Cilofexor price.
  • $39 - $1400
  • Product name: Cilofexor
  • CAS: 1418274-28-8
  • MF: C28H22Cl3N3O5
  • MW: 586.85
  • EINECS:
  • MDL Number:MFCD31731099
  • Synonyms:Cilofexor;Cilofexor (GS-9674);2-(3-(2-chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)phenyl)-3-hydroxyazetidin-1-yl)isonicotinic acid;GS-9674;GS9674;CILOFEXOR;CS-2761;2-[3-(2-chloro-4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid;4-Pyridinecarboxylic acid, 2-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-;GS9674,Inhibitor,inhibit,NR1H4,FXR,Cilofexor,PSC,GS 9674,oral,NASH,GS-9674,antifibrotic,nonsteroidal,anti-inflammatory,Autophagy,safety
12 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number2668DU
  • Product descriptionCilofexor
  • Packaging5mg
  • Price$276
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25747
  • Product descriptionCilofexor ≥98%
  • Packaging1mg
  • Price$39
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25747
  • Product descriptionCilofexor ≥98%
  • Packaging5mg
  • Price$202
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25747
  • Product descriptionCilofexor ≥98%
  • Packaging10mg
  • Price$363
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25747
  • Product descriptionCilofexor ≥98%
  • Packaging25mg
  • Price$745
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0039260
  • Product descriptionCilofexor 99.82%
  • Packaging5mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0039260
  • Product descriptionCilofexor 99.82%
  • Packaging10mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0039260
  • Product descriptionCilofexor 99.82%
  • Packaging25mg
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0039260
  • Product descriptionCilofexor 99.82%
  • Packaging50mg
  • Price$840
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0039260
  • Product descriptionCilofexor 99.82%
  • Packaging100mg
  • Price$1400
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10868
  • Product descriptionCilofexor >98%
  • Packaging100mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10868
  • Product descriptionCilofexor >98%
  • Packaging250mg
  • Price$1200
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2668DU Cilofexor 5mg $276 2021-12-16 Buy
Cayman Chemical 25747 Cilofexor ≥98% 1mg $39 2024-03-01 Buy
Cayman Chemical 25747 Cilofexor ≥98% 5mg $202 2024-03-01 Buy
Cayman Chemical 25747 Cilofexor ≥98% 10mg $363 2024-03-01 Buy
Cayman Chemical 25747 Cilofexor ≥98% 25mg $745 2024-03-01 Buy
ChemScene CS-0039260 Cilofexor 99.82% 5mg $150 2021-12-16 Buy
ChemScene CS-0039260 Cilofexor 99.82% 10mg $240 2021-12-16 Buy
ChemScene CS-0039260 Cilofexor 99.82% 25mg $490 2021-12-16 Buy
ChemScene CS-0039260 Cilofexor 99.82% 50mg $840 2021-12-16 Buy
ChemScene CS-0039260 Cilofexor 99.82% 100mg $1400 2021-12-16 Buy
DC Chemicals DC10868 Cilofexor >98% 100mg $700 2021-12-16 Buy
DC Chemicals DC10868 Cilofexor >98% 250mg $1200 2021-12-16 Buy

Properties

Boiling point :855.5±65.0 °C(Predicted)
Density :1.538±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:32.5(Max Conc. mg/mL);55.38(Max Conc. mM)
form :A crystalline solid
pka :2.10±0.10(Predicted)
color :Off-white to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Cilofexor inhibits binding of a synthetic peptide, comprising residues 676-700 of the steroid receptor coactivator 1 (SRC-1), to the farnesoid X receptor (FXR; EC50 = <25 nM in a FRET activity assay). It has FXR agonist activity in a mammalian one hybrid (M1H) assay (EC50 = ≥100 nM).