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ChemicalBook >> CAS DataBase List >> Cyclo(L-Phe-L-Val)

Cyclo(L-Phe-L-Val)

Cyclo(L-Phe-L-Val) price.
  • $242 - $1174
  • Product name: Cyclo(L-Phe-L-Val)
  • CAS: 35590-86-4
  • MF: C14H18N2O2
  • MW: 246.3
  • EINECS:
  • MDL Number:MFCD33021199
  • Synonyms:Cyclo(L-Phe-L-Val);(3S,6S)-3-(1-methylethyl)-6-(phenylmethyl)piperazine-2,5-dione;Cyclo(-L-Val-L-Phe);2,5-Piperazinedione, 3-(1-methylethyl)-6-(phenylmethyl)-, (3S,6S)-;3S-(1-methylethyl)-6S-(phenylmethyl)-2,5-piperazinedione;(3S,6S)-3-benzyl-6-isopropylpiperazine-2,5-dione
3 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 5mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number9259CU
  • Product description(3S,6S)-3-Benzyl-6-isopropyl-piperazine-2,5-dione
  • Packaging25mg
  • Price$1174
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number24943
  • Product descriptionCyclo(L-Phe-L-Val) ≥95%
  • Packaging5mg
  • Price$242
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24943
  • Product descriptionCyclo(L-Phe-L-Val) ≥95%
  • Packaging25mg
  • Price$965
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9259CU (3S,6S)-3-Benzyl-6-isopropyl-piperazine-2,5-dione 25mg $1174 2021-12-16 Buy
Cayman Chemical 24943 Cyclo(L-Phe-L-Val) ≥95% 5mg $242 2024-03-01 Buy
Cayman Chemical 24943 Cyclo(L-Phe-L-Val) ≥95% 25mg $965 2024-03-01 Buy

Properties

Melting point :176-178 °C
Boiling point :515.6±43.0 °C(Predicted)
Density :1.109±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form :A solid
pka :13.12±0.60(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Cyclo(L-Phe-L-Val) is a metabolite of the sponge bacterium Pseudoalteromonas sp. NJ6-3-1 that can autoinduce production of antibacterial substances active against S. aureus when co-cultured at a low cell density. It induces neurite outgrowth and branching of chick cortical neurons in vitro when used at concentrations of 16 and 32 μM. It increases phosphorylation of the PI3K substrate Akt, and neurite outgrowth induced by cyclo(L-Phe-L-Val) can be blocked by the PI3K inhibitor LY294002 . Cyclo(L-Phe-L-Val) enhances axon sprouting of calcitonin gene-related protein positive (CGRP+) primary afferents in the spinal cord following crush injury and of serotonin neurons in uninjured spinal cord. Cyclo(L-Phe-L-Val) is also a bitter taste component of cocoa and roasted coffee.