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ChemicalBook >> DAz-2

DAz-2

DAz-2 price.
  • $62 - $878.9
  • Product name: DAz-2
  • CAS: 1176905-54-6
  • MF: C9H13N3O2
  • MW: 195.21842
  • EINECS:
  • MDL Number:
  • Synonyms:DAz-2;ANTI-DAZ2 (C-TERM) antibody produced in rabbit;Deleted in azoospermia protein 2;4-(3-azidopropyl)cyclohexane-1,3-dione
5 prices
Selected condition:
Brand
  • AK Scientific
  • Biorbyt Ltd
  • Cayman Chemical
Package
  • 10μg
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number6984DK
  • Product description4-(3-Azidopropyl)cyclohexane-1,3-dione
  • Packaging1mg
  • Price$166
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb532098
  • Product descriptionDAZ2
  • Packaging10μg
  • Price$878.9
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13382
  • Product descriptionDAz-2 ≥98%
  • Packaging1mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13382
  • Product descriptionDAz-2 ≥98%
  • Packaging5mg
  • Price$208
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13382
  • Product descriptionDAz-2 ≥98%
  • Packaging10mg
  • Price$387
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6984DK 4-(3-Azidopropyl)cyclohexane-1,3-dione 1mg $166 2021-12-16 Buy
Biorbyt Ltd orb532098 DAZ2 10μg $878.9 2021-12-16 Buy
Cayman Chemical 13382 DAz-2 ≥98% 1mg $62 2024-03-01 Buy
Cayman Chemical 13382 DAz-2 ≥98% 5mg $208 2024-03-01 Buy
Cayman Chemical 13382 DAz-2 ≥98% 10mg $387 2024-03-01 Buy

Properties

storage temp. :-20°C
solubility :DMF: 20 mg/ml; DMSO: 14 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS (pH 7.2) (1:10): 0.1 mg/ml
form :A crystalline solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

DAz-2 is a cell-permeable chemical probe used to detect cysteine oxidation in proteins. Redox-sensitive cysteine residues in proteins may function as sensors of reactive oxygen species (ROS) and also serve as molecular switches, activating or deactivating proteins, following a change in oxidation state. Modification of protein function through the reversible oxidation of cysteine is emerging as a biologically relevant signal transduction mechanism. Sulfenic acid is the initial oxidation product of cysteine by relatively mild oxidizing agents such as hydrogen peroxide. Sulfenic acid can be reduced back to the free thiol or be further oxidized to sulfinic and sulfonic acids. DAz-2 is a cell-permeable chemical probe that reacts specifically with sulfenic acid-modified proteins. The azido group of DAz-2 provides a method for selective conjugation to phosphine- or alkynyl- derivatized reagents, such as biotin or various fluorophores, for subsequent analysis of the labeled proteins. Use of DAz-2 in HeLa cells followed by Staudinger ligation to biotin and subsequent LC-MS/MS analysis, led to the identification of 193 sulfenic acid-modified proteins having a diverse range of functions.