DEGUELIN
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- $39 - $1800
- Product name: DEGUELIN
- CAS: 522-17-8
- MF: C23H22O6
- MW: 394.42
- EINECS:200-258-5
- MDL Number:MFCD01740600
- Synonyms:(7as-cis)-oxy- ;3h-bis(1)benzopyrano(3,4-b:6’,5’-e)pyran-7(7ah)-one,13,13a-dihydro-9,10-dimeth ;(7AS,13AS)-13,13A-DIHYDRO-9,10-DIMETHOXY-3,3-DIMETHYL-3H-BIS[1]BENZOPYRANO[3,4-B:6',5'-E]PYRAN-7(7AH)-ONE;(-)-DEGUELIN;DEGUELIN;(7aS,13aS)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-(3H)-bis[1]benzopyrano[3.4-b.6'.5'-e]pyran-7(7aH)-one;(7aS)-3,3-Dimethyl-9,10-dimethoxy-7,7aα,13,13aα-tetrahydro-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7-one;3,3-Dimethyl-9,10-dimethoxy-7,7aα,13,13aα-tetrahydro-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7-one
38 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number1702AH
- Product descriptionDeguelin
- Packaging50mg
- Price$522
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA139886
- Product description(7aS,13aS)-9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-pyrano[2,3-c:6,5-f']dichromen-7(7aH)-one 98+%
- Packaging5mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA139886
- Product description(7aS,13aS)-9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-pyrano[2,3-c:6,5-f']dichromen-7(7aH)-one 98+%
- Packaging10mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA139886
- Product description(7aS,13aS)-9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-pyrano[2,3-c:6,5-f']dichromen-7(7aH)-one 98+%
- Packaging100mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000092
- Product descriptionDEGUELIN 95.00%
- Packaging5MG
- Price$637.79
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000092
- Product descriptionDEGUELIN 95.00%
- Packaging10MG
- Price$756
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000092
- Product descriptionDEGUELIN 95.00%
- Packaging50MG
- Price$1050.24
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4451
- Product descriptionDeguelin
- Packaging5mg
- Price$78
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4451
- Product descriptionDeguelin
- Packaging10mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4451
- Product descriptionDeguelin
- Packaging50mg
- Price$504
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS036629
- Product descriptionDeguelin ≥98%
- Packaging5mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS036629
- Product descriptionDeguelin ≥98%
- Packaging10mg
- Price$71
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS036629
- Product descriptionDeguelin ≥98%
- Packaging50mg
- Price$217
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN97934
- Product descriptionDeguelin ≥98%
- Packaging5mg
- Price$283
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS036629
- Product descriptionDeguelin ≥98%
- Packaging100mg
- Price$346
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1239
- Product descriptionDeguelin 98%
- Packaging10mg
- Price$148.5
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1702AH | Deguelin | 50mg | $522 | 2021-12-16 | Buy |
| Ambeed | A139886 | (7aS,13aS)-9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-pyrano[2,3-c:6,5-f']dichromen-7(7aH)-one 98+% | 5mg | $39 | 2021-12-16 | Buy |
| Ambeed | A139886 | (7aS,13aS)-9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-pyrano[2,3-c:6,5-f']dichromen-7(7aH)-one 98+% | 10mg | $72 | 2021-12-16 | Buy |
| Ambeed | A139886 | (7aS,13aS)-9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-pyrano[2,3-c:6,5-f']dichromen-7(7aH)-one 98+% | 100mg | $350 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000092 | DEGUELIN 95.00% | 5MG | $637.79 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000092 | DEGUELIN 95.00% | 10MG | $756 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000092 | DEGUELIN 95.00% | 50MG | $1050.24 | 2021-12-16 | Buy |
| ApexBio Technology | A4451 | Deguelin | 5mg | $78 | 2021-12-16 | Buy |
| ApexBio Technology | A4451 | Deguelin | 10mg | $138 | 2021-12-16 | Buy |
| ApexBio Technology | A4451 | Deguelin | 50mg | $504 | 2021-12-16 | Buy |
| Arctom | AS036629 | Deguelin ≥98% | 5mg | $39 | 2021-12-16 | Buy |
| Arctom | AS036629 | Deguelin ≥98% | 10mg | $71 | 2021-12-16 | Buy |
| Arctom | AS036629 | Deguelin ≥98% | 50mg | $217 | 2021-12-16 | Buy |
| Arctom | CFN97934 | Deguelin ≥98% | 5mg | $283 | 2021-12-16 | Buy |
| Arctom | AS036629 | Deguelin ≥98% | 100mg | $346 | 2021-12-16 | Buy |
| Axon Medchem | Axon1239 | Deguelin 98% | 10mg | $148.5 | 2021-12-16 | Buy |
Properties
Melting point :85-87 °C(lit.)
Boiling point :560.1±50.0 °C(Predicted)
alpha :D27 -97.2° (c = 0.2 in benzene)
Density :1?+-.0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >10 mg/mL
form :solid
color :white to yellow
optical activity :[α]/D -70 to -80°, c = 0.2 in methanol
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Boiling point :560.1±50.0 °C(Predicted)
alpha :D27 -97.2° (c = 0.2 in benzene)
Density :1?+-.0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >10 mg/mL
form :solid
color :white to yellow
optical activity :[α]/D -70 to -80°, c = 0.2 in methanol
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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Description
Deguelin is a natural product that displays profound antiproliferative activity. Deguelin induces apoptosis, mediated through AKT/PKB signaling pathways in malignant and premaligant human bronchial epithelia (HBE) cells, with only minimal effects on normal HBE cells. Deguelin inhibits AKT by both PI 3-kinase dependent and PI 3-kinase independent pathways. Deguelin has displayed anti-tumor lymphangiogenesis and lymphatic metastasis by down-regulation of vascular endothelial cell growth factor-D in tumor models. Deguelin has also been shown to inhibit Cox-2 expression.More related product prices
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