Denbufylline
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- $80 - $1593.9
- Product name: Denbufylline
- CAS: 57076-71-8
- MF: C16H24N4O3
- MW: 320.39
- EINECS:
- MDL Number:MFCD00867152
- Synonyms:3,7-dihydro-1,3-dibutyl-7-(2-oxopropyl)-1h-purine-2,6-dione ;3,7-dihydro-1,3-dibutyl-7-(2-oxopropyl)-1h-purine-6-dione ;brl30892 ;1,3-DI-N-BUTYL-7-(2'-OXOPROPYL)XANTHINE;DENBUFYLLINE;1,3-Dibutyl-3,7-dihydro-7-(2-oxopropyl)-1H-purine-2,6-dione;7-Acetonyl-1,3-dibutyl-3,7-dihydro-1H-purine-2,6-dione;1H-Purine-2,6-dione, 1,3-dibutyl-3,7-dihydro-7-(2-oxopropyl)-
10 prices
Selected condition：
Brand
- AHH
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- TRC
- Usbiological
Package
- 5mg
- 10MG
- 0.025g
- 25mg
- 50mg
- 100MG
- ManufacturerAHH
- Product numberMT-49842
- Product descriptionDenbufylline 98%
- Packaging0.025g
- Price$310
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002248
- Product descriptionDENBUFYLLINE 95.00%
- Packaging10MG
- Price$269.85
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002248
- Product descriptionDENBUFYLLINE 95.00%
- Packaging100MG
- Price$1593.9
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD21036
- Product descriptionDenbufylline
- Packaging5mg
- Price$109.9
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD21036
- Product descriptionDenbufylline
- Packaging10mg
- Price$199.9
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD21036
- Product descriptionDenbufylline
- Packaging25mg
- Price$425
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD21036
- Product descriptionDenbufylline
- Packaging50mg
- Price$830
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD21036
- Product descriptionDenbufylline
- Packaging100mg
- Price$1280
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberD231400
- Product descriptionDenbufylline
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product numberD2743
- Product descriptionDenbufylline
- Packaging10mg
- Price$403
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-49842 | Denbufylline 98% | 0.025g | $310 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002248 | DENBUFYLLINE 95.00% | 10MG | $269.85 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002248 | DENBUFYLLINE 95.00% | 100MG | $1593.9 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21036 | Denbufylline | 5mg | $109.9 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21036 | Denbufylline | 10mg | $199.9 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21036 | Denbufylline | 25mg | $425 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21036 | Denbufylline | 50mg | $830 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21036 | Denbufylline | 100mg | $1280 | 2021-12-16 | Buy |
| TRC | D231400 | Denbufylline | 5mg | $80 | 2021-12-16 | Buy |
| Usbiological | D2743 | Denbufylline | 10mg | $403 | 2021-12-16 | Buy |
Properties
Melting point :98-100°C
Boiling point :514.8±56.0 °C(Predicted)
Density :1.23±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO, Methanol
form :Solid
pka :-0.17±0.70(Predicted)
color :Off-White to Pale Beige
CAS DataBase Reference :57076-71-8
Boiling point :514.8±56.0 °C(Predicted)
Density :1.23±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO, Methanol
form :Solid
pka :-0.17±0.70(Predicted)
color :Off-White to Pale Beige
CAS DataBase Reference :57076-71-8
Safety Information
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Description
Denbufylline, a xanthine derivative and PDE4 inhibitor, has effects such as vasodilatation of cerebral vessels (Willette et al., 1997) and potent activation of the hypothalamic–pituitary–adrenal axis. PDE4 is one of the cyclic adenosine monophosphate (cAMP)–specic phosphodiesterases whose tissue distribution is important in pathologies related to the central nervous and immune systems. In experimental animals, denbufylline increases adrenocorticotropic hormone (ACTH), circulating corticosterone, luteinizing hormone, corticotrophin-releasing hormone, and cAMP content of the hypothalamic tissue, but is without effect on arginine vasopressin (Kumari et al., 1997). Treves and Korczyn (1999) studied patients with AD, mixed dementia, and VaD treated with denbufylline. No signicant differences were found in comparison with placebo for the treatment of AD or VaD, although patients who received denbufylline tended to improve their cognitive scores.Related product price
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$80-1593.9 - 31542-63-9
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