Welcome to chemicalbook!
400-158-6606
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> DL-TBOA

DL-TBOA

DL-TBOA price.
  • $184 - $1425
  • Product name: DL-TBOA
  • CAS: 205309-81-5
  • MF: C11H13NO5
  • MW: 239.22
  • EINECS:
  • MDL Number:MFCD03093854
  • Synonyms:DL-THREO-BETA-BENZYLOXYASPARTIC ACID;D,L-THREO-B-BENZYLOXYASPARTATE;DL-TBOA;DL-threo-β-Benzyloxyasparticacid;D-Aspartic acid, 3-(phenylmethoxy)-, (3R)-rel-;BYOBCYXURWDEDS-IUCAKERBSA-N;DLTBOA,DL TBOA
10 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Tocris
  • TRC
Package
  • 50
  • 5MG
  • 10mg
  • 10
  • 50mg
  • 100mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAAA0017089
  • Product descriptionDL-TBOA 95.00%
  • Packaging5MG
  • Price$499.22
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5084
  • Product descriptionDL-TBOA
  • Packaging10mg
  • Price$339
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5084
  • Product descriptionDL-TBOA
  • Packaging50mg
  • Price$1425
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29632
  • Product descriptionDL-TBOA
  • Packaging5mg
  • Price$184
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29632
  • Product descriptionDL-TBOA
  • Packaging10mg
  • Price$330
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0028700
  • Product descriptionDL-TBOA 99.68%
  • Packaging5mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0028700
  • Product descriptionDL-TBOA 99.68%
  • Packaging10mg
  • Price$860
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number1223
  • Product descriptionDL-TBOA ≥98%(HPLC)
  • Packaging10
  • Price$231
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number1223
  • Product descriptionDL-TBOA ≥98%(HPLC)
  • Packaging50
  • Price$971
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberD525375
  • Product descriptionDL-TBOA
  • Packaging100mg
  • Price$1260
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation AAA0017089 DL-TBOA 95.00% 5MG $499.22 2021-12-16 Buy
ApexBio Technology B5084 DL-TBOA 10mg $339 2021-12-16 Buy
ApexBio Technology B5084 DL-TBOA 50mg $1425 2021-12-16 Buy
Cayman Chemical 29632 DL-TBOA 5mg $184 2024-03-01 Buy
Cayman Chemical 29632 DL-TBOA 10mg $330 2024-03-01 Buy
ChemScene CS-0028700 DL-TBOA 99.68% 5mg $500 2021-12-16 Buy
ChemScene CS-0028700 DL-TBOA 99.68% 10mg $860 2021-12-16 Buy
Tocris 1223 DL-TBOA ≥98%(HPLC) 10 $231 2021-12-16 Buy
Tocris 1223 DL-TBOA ≥98%(HPLC) 50 $971 2021-12-16 Buy
TRC D525375 DL-TBOA 100mg $1260 2021-12-16 Buy

Properties

Boiling point :421.7±45.0 °C(Predicted)
Density :1.392±0.06 g/cm3(Predicted)
storage temp. :Desiccate at -20°C
solubility :<23.92mg/ml in DMSO;insoluble in H2O
form :solid
pka :2.07±0.27(Predicted)
color :White

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

DL-TBOA is an inhibitor of excitatory amino acid transporters (EAATs), with IC50 values of 67 and 5.5 μM for glutamate uptake in COS-1 cells expressing human EAAT1 and EAAT2, respectively. It inhibits inward currents induced by L-aspartate in EAAT4-expressing Xenopus oocytes (Ki = 4.4 μM) and by L-glutamate in EAAT5-expressing oocytes (Ki = 3.2 μM) voltage-clamped at -60 mV. In vivo, DL-TBOA (500 μM, intrahippocampal perfusion) increases extracellular aspartate, glutamate, and alanine levels in rat hippocampus. Intrahippocampal injection of DL-TBOA increases lesion volume in the rat CA1 region in a dose-dependent manner and induces hyperexcitability, wet-dog shakes, salivation, forelimb myoclonus, limbic seizures, and epileptic EEG discharges at a dose of 25 nmol. DL-TBOA (5 and 10 μg, intrathecal) induces antinociception in the second phase of the formalin test in rats when administered 10 minutes prior to formalin.