Doxorubicinone
|
- $68 - $2090
- Product name: Doxorubicinone
- CAS: 24385-10-2
- MF: C21H18O9
- MW: 414.36
- EINECS:
- MDL Number:MFCD00871832
- Synonyms:Epirubicin aglycon;5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-;Ccris 7633;8-glycoloyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-Naphthacenedione;Doxorubicin aglycone;Doxorubicinone;Epirubicin aglycone;5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-
15 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- Cayman Chemical
- Chemtos
- Medical Isotopes, Inc.
- TRC
Package
- 500μg
- 1mg
- 2MG
- 5mg
- 10MG
- 20MG
- 50mg
- ManufacturerAK Scientific
- Product number9667AJ
- Product descriptionDoxorubicinone
- Packaging5mg
- Price$768
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0000544
- Product descriptionDOXORUBICINONE 95.00%
- Packaging2MG
- Price$742.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0000544
- Product descriptionDOXORUBICINONE 95.00%
- Packaging10MG
- Price$1754.55
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0000544
- Product descriptionDOXORUBICINONE 95.00%
- Packaging20MG
- Price$2090
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD22607
- Product descriptionDoxorubicinone
- Packaging1mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD22607
- Product descriptionDoxorubicinone
- Packaging2mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD22607
- Product descriptionDoxorubicinone
- Packaging5mg
- Price$900
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21693
- Product descriptionDoxorubicinone ≥98%
- Packaging500μg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21693
- Product descriptionDoxorubicinone ≥98%
- Packaging1mg
- Price$130
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21693
- Product descriptionDoxorubicinone ≥98%
- Packaging5mg
- Price$601
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21693
- Product descriptionDoxorubicinone ≥98%
- Packaging10mg
- Price$1031
- Updated2024-03-01
- Buy
- ManufacturerChemtos
- Product numberD-2561
- Product descriptionDoxorubicinone
- Packaging10mg
- Price$1100
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number9816
- Product descriptionDoxorubicinone
- Packaging1mg
- Price$490
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberD559070
- Product descriptionDoxorubicinone
- Packaging5mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberD559070
- Product descriptionDoxorubicinone
- Packaging50mg
- Price$1390
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 9667AJ | Doxorubicinone | 5mg | $768 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0000544 | DOXORUBICINONE 95.00% | 2MG | $742.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0000544 | DOXORUBICINONE 95.00% | 10MG | $1754.55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0000544 | DOXORUBICINONE 95.00% | 20MG | $2090 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD22607 | Doxorubicinone | 1mg | $220 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD22607 | Doxorubicinone | 2mg | $400 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD22607 | Doxorubicinone | 5mg | $900 | 2021-12-16 | Buy |
| Cayman Chemical | 21693 | Doxorubicinone ≥98% | 500μg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 21693 | Doxorubicinone ≥98% | 1mg | $130 | 2024-03-01 | Buy |
| Cayman Chemical | 21693 | Doxorubicinone ≥98% | 5mg | $601 | 2024-03-01 | Buy |
| Cayman Chemical | 21693 | Doxorubicinone ≥98% | 10mg | $1031 | 2024-03-01 | Buy |
| Chemtos | D-2561 | Doxorubicinone | 10mg | $1100 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 9816 | Doxorubicinone | 1mg | $490 | 2021-12-16 | Buy |
| TRC | D559070 | Doxorubicinone | 5mg | $180 | 2021-12-16 | Buy |
| TRC | D559070 | Doxorubicinone | 50mg | $1390 | 2021-12-16 | Buy |
Properties
Melting point :223-225°C
Boiling point :741.2±60.0 °C(Predicted)
Density :1.671±0.06 g/cm3(Predicted)
storage temp. :Amber Vial, -20°C Freezer
solubility :Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :7.45±0.60(Predicted)
color :Red to Very Dark Red
Stability :Light Sensitive
InChI :InChI=1S/C21H18O9/c1-30-11-4-2-3-8-14(11)20(28)16-15(17(8)25)18(26)9-5-21(29,12(24)7-22)6-10(23)13(9)19(16)27/h2-4,10,22-23,26-27,29H,5-7H2,1H3/t10-,21-/m0/s1
InChIKey :IBZGBXXTIGCACK-CWKPULSASA-N
SMILES :C1(OC)=C2C(C(=O)C3=C(C2=O)C(O)=C2C(C[C@@](O)(C(CO)=O)C[C@@H]2O)=C3O)=CC=C1
CAS DataBase Reference :24385-10-2
Boiling point :741.2±60.0 °C(Predicted)
Density :1.671±0.06 g/cm3(Predicted)
storage temp. :Amber Vial, -20°C Freezer
solubility :Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :7.45±0.60(Predicted)
color :Red to Very Dark Red
Stability :Light Sensitive
InChI :InChI=1S/C21H18O9/c1-30-11-4-2-3-8-14(11)20(28)16-15(17(8)25)18(26)9-5-21(29,12(24)7-22)6-10(23)13(9)19(16)27/h2-4,10,22-23,26-27,29H,5-7H2,1H3/t10-,21-/m0/s1
InChIKey :IBZGBXXTIGCACK-CWKPULSASA-N
SMILES :C1(OC)=C2C(C(=O)C3=C(C2=O)C(O)=C2C(C[C@@](O)(C(CO)=O)C[C@@H]2O)=C3O)=CC=C1
CAS DataBase Reference :24385-10-2
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | |||||||||||||||||||||||||||||||||||||||||||||||||
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Description
Doxorubicinone is a metabolite of the anthracycline antitumor antibiotic doxorubicin . Doxorubicinone inhibits mitochondrial succinoxidase from bovine heart and reduces the mitochondrial inner membrane potential in rat heart and liver mitochondria in a concentration-dependent manner. Doxorubicinone (40 μM) increases pentose phosphate pathway flux by 45% and reduces activity of glutathione peroxidase (GPx) and superoxide dismutase (SOD) by 17 and 60%, respectively, in human erythrocytes. It also induces cytotoxicity in patient-derived ovarian cancer colonies in a concentration-dependent manner.Related product price
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