Dutasteride
- $50 - $1732.5
- Product name: Dutasteride
- CAS: 164656-23-9
- MF: C27H30F6N2O2
- MW: 528.53
- EINECS:638-758-5
- MDL Number:MFCD00937869
- Synonyms:(1S,2R,7R,10S,11S,14S,15S)-N-[2,5-bis(trifluoroMethyl)phenyl]-2,15-diMethyl-5-oxo-6-azatetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-3-ene-14-carboxaMide;(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoroMethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-diMethyl-2-oxo-1H-Indeno[5,4-f]quinoline-7-carboxaMide;(5α,17β)-;(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoroMethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-diMethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxaMide-13C6;6β-Hydroxy Dutasteride;4-Azaandrost-1-ene-17-carboxaMide, N-[2,5-bis(trifluoroMethyl)phenyl]-3-oxo-, (5a,17b)-;Avolve;Dutasteride API
27 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 250mg
- 1g
- 200mg
- y0001598
- y0001603
- 5MG
- 10MG
- 100MG
- 500mg
- 50mg
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product numberJ10036
- Product descriptionDutasteride
- Packaging50mg
- Price$161
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ95466
- Product descriptionDutasteride
- Packaging500mg
- Price$181
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberF281
- Product descriptionDutasteride
- Packaging500mg
- Price$242
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0006453
- Product descriptionDUTASTERIDE 95.00%
- Packaging5MG
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0006453
- Product descriptionDUTASTERIDE 95.00%
- Packaging10MG
- Price$721.88
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0006453
- Product descriptionDUTASTERIDE 95.00%
- Packaging100MG
- Price$1732.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1659
- Product descriptionDutasteride
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1659
- Product descriptionDutasteride
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBD164398
- Product descriptionDutasteride
- Packaging10mg
- Price$54
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBD164398
- Product descriptionDutasteride
- Packaging50mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15956
- Product descriptionDutasteride ≥98%
- Packaging5mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15956
- Product descriptionDutasteride ≥98%
- Packaging10mg
- Price$130
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15956
- Product descriptionDutasteride ≥98%
- Packaging50mg
- Price$370
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15956
- Product descriptionDutasteride ≥98%
- Packaging100mg
- Price$669
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-1542
- Product descriptionDutasteride 99.75%
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1542
- Product descriptionDutasteride 99.75%
- Packaging50mg
- Price$120
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | J10036 | Dutasteride | 50mg | $161 | 2021-12-16 | Buy |
AK Scientific | J95466 | Dutasteride | 500mg | $181 | 2021-12-16 | Buy |
AK Scientific | F281 | Dutasteride | 500mg | $242 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | SHG0006453 | DUTASTERIDE 95.00% | 5MG | $550 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | SHG0006453 | DUTASTERIDE 95.00% | 10MG | $721.88 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | SHG0006453 | DUTASTERIDE 95.00% | 100MG | $1732.5 | 2021-12-16 | Buy |
ApexBio Technology | A1659 | Dutasteride | 10mg | $50 | 2021-12-16 | Buy |
ApexBio Technology | A1659 | Dutasteride | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
Biosynth Carbosynth | BD164398 | Dutasteride | 10mg | $54 | 2021-12-16 | Buy |
Biosynth Carbosynth | BD164398 | Dutasteride | 50mg | $108 | 2021-12-16 | Buy |
Cayman Chemical | 15956 | Dutasteride ≥98% | 5mg | $68 | 2024-03-01 | Buy |
Cayman Chemical | 15956 | Dutasteride ≥98% | 10mg | $130 | 2024-03-01 | Buy |
Cayman Chemical | 15956 | Dutasteride ≥98% | 50mg | $370 | 2024-03-01 | Buy |
Cayman Chemical | 15956 | Dutasteride ≥98% | 100mg | $669 | 2024-03-01 | Buy |
ChemScene | CS-1542 | Dutasteride 99.75% | 10mg | $60 | 2021-12-16 | Buy |
ChemScene | CS-1542 | Dutasteride 99.75% | 50mg | $120 | 2021-12-16 | Buy |
Properties
Melting point :242-250°C
Boiling point :620.3±55.0 °C(Predicted)
Density :1.303±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble2mg/mL, clear
pka :13.32±0.70(Predicted)
form :powder
color :white to beige
optical activity :[α]/D +18 to +24°, c = 1 in chloroform-d
BCS Class :2/4
InChIKey :JWJOTENAMICLJG-QWBYCMEYSA-N
SMILES :N1[C@@]2([H])[C@@](C)([C@@]3([H])CC[C@@]4(C)[C@]([H])([C@]3([H])CC2)CC[C@@H]4C(NC2=CC(C(F)(F)F)=CC=C2C(F)(F)F)=O)C=CC1=O
Boiling point :620.3±55.0 °C(Predicted)
Density :1.303±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble2mg/mL, clear
pka :13.32±0.70(Predicted)
form :powder
color :white to beige
optical activity :[α]/D +18 to +24°, c = 1 in chloroform-d
BCS Class :2/4
InChIKey :JWJOTENAMICLJG-QWBYCMEYSA-N
SMILES :N1[C@@]2([H])[C@@](C)([C@@]3([H])CC[C@@]4(C)[C@]([H])([C@]3([H])CC2)CC[C@@H]4C(NC2=CC(C(F)(F)F)=CC=C2C(F)(F)F)=O)C=CC1=O
Safety Information
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Signal word: | Danger | ||||||||||||||
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Description
5α-reductase catalyzes the NADPH-dependent reduction of Δ4,5 double bonds in several steroid substrates, including testosterone , which is converted to dihydrotestosterone, the primary mediator of prostate growth. The 5α-reductase enzymes responsible for the reduction of testosterone to dihydrotestosterone exist as two forms: type I, which occurs in the skin, liver, and ventral prostate and type II, which is expressed in ventral prostate, epididymis, and other reproductive tissues. Dutasteride is a time-dependent, dual inhibitor of 5α-reductase (apparent Kis = 17 and 4.3 nM at 10 and 30 minute reaction times, respectively) that is frequently used in the treatment of benign prostatic hyperplasia. Compared to finasteride , a selective inhibitor of type II 5α-reductase, dutasteride has a greater terminal half-life (1 vs. 14 hours in rat, respectively) and is more effective at decreasing serum levels of dihydrotestosterone at single doses > 10 mg. Dutasteride has also been used as a strategy to reduce androgen levels related to prostate tumor burden on androgen receptor activity.More related product prices
Diphenyl oxide Finasteride 433-19-2 2,5-Bis(trifluoromethyl)aniline METHYL 4-AZA-5ALPHA-ANDROSTA-1-EN-3-ONE-17BETA-CARBOXYLATE 5β-Dutasteride 2,6-BIS(TRIFLUOROMETHYL)ANILINE 4-Aza-5a-androstan-1-ene-3-one-17b-carboxylic acid 3,4-Bis-trifluoromethyl-phenylamine 320-88-7 3-Oxo-4-aza-5-alpha-androstane-17-beta-carboxylic acid (5ALPHA,17BETA)-N-(2-HYDROXY-1,1-DIMETHYLETHYL)-3-OXO-4-AZAANDROST-1-ENE-17-CARBOXAMIDE Dutasteride Chloro IMpurity Phenylacetic acid 1,4-BIS(DIFLUOROMETHYL)BENZENERelated product price
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$5-700 - PHENYL VALERATE
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$26-845
Suppliers and manufacturers
HEBEI Meijinnong Import And Export Trade Co.,LTD