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ChemicalBook >> CAS DataBase List >> EIPA

EIPA

EIPA price.
  • $55 - $1593.9
  • Product name: EIPA
  • CAS: 1154-25-2
  • MF: C11H18ClN7O
  • MW: 299.76
  • EINECS:
  • MDL Number:MFCD00151710
  • Synonyms:AMILORIDE, 5-(N-ETHYL-N-ISOPROPYL)-;5-(N-ETHYL-N-ISOPROPYL)AMILORIDE;3-AMINO-N-(AMINOIMINOMETHYL)-6-CHLORO-5-[ETHYL(2-PROPYL)AMINO]-PYRAZINE-2-CARBOXAMIDE;EIPA;3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide;L 593754;MH 12-43;3-Amino-5-(N-ethyl-N-isopropylamino)-6-chloro-N-(aminoiminomethyl)-2-pyrazinecarboxamide
27 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 5mg
  • 10mg
  • 25mg
  • 50
  • 50mg
  • 100mg
  • 0.25g
  • 250MG
  • ManufacturerAHH
  • Product numberMT-12489
  • Product description5-(N-Ethyl-N-Isopropyl)Amiloride 98%
  • Packaging0.25g
  • Price$388
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2846AL
  • Product description5-(N-Ethyl-N-isopropyl)amiloride
  • Packaging5mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number1154252
  • Product description3-Amino-N-carbamimidoyl-6-chloro-5-(ethyl(isopropyl)amino)pyrazine-2-carboxamide
  • Packaging25mg
  • Price$356.31
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number1154252
  • Product description3-Amino-N-carbamimidoyl-6-chloro-5-(ethyl(isopropyl)amino)pyrazine-2-carboxamide
  • Packaging100mg
  • Price$899.64
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA367526
  • Product description3-Amino-N-carbamimidoyl-6-chloro-5-(ethyl(isopropyl)amino)pyrazine-2-carboxamide 98%
  • Packaging25mg
  • Price$152
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA367526
  • Product description3-Amino-N-carbamimidoyl-6-chloro-5-(ethyl(isopropyl)amino)pyrazine-2-carboxamide 98%
  • Packaging50mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA367526
  • Product description3-Amino-N-carbamimidoyl-6-chloro-5-(ethyl(isopropyl)amino)pyrazine-2-carboxamide 98%
  • Packaging100mg
  • Price$395
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0002058
  • Product description5-(N-ETHYL-N-ISOPROPYL)AMILORIDE 95.00%
  • Packaging5MG
  • Price$168.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0002058
  • Product description5-(N-ETHYL-N-ISOPROPYL)AMILORIDE 95.00%
  • Packaging25MG
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0002058
  • Product description5-(N-ETHYL-N-ISOPROPYL)AMILORIDE 95.00%
  • Packaging250MG
  • Price$1593.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7389
  • Product descriptionEIPA
  • Packaging5mg
  • Price$62
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7389
  • Product descriptionEIPA
  • Packaging10mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7389
  • Product descriptionEIPA
  • Packaging25mg
  • Price$203
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14406
  • Product description5-(N-ethyl-N-isopropyl)-Amiloride ≥98%
  • Packaging5mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14406
  • Product description5-(N-ethyl-N-isopropyl)-Amiloride ≥98%
  • Packaging10mg
  • Price$107
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14406
  • Product description5-(N-ethyl-N-isopropyl)-Amiloride ≥98%
  • Packaging25mg
  • Price$179
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-12489 5-(N-Ethyl-N-Isopropyl)Amiloride 98% 0.25g $388 2021-12-16 Buy
AK Scientific 2846AL 5-(N-Ethyl-N-isopropyl)amiloride 5mg $160 2021-12-16 Buy
Alichem 1154252 3-Amino-N-carbamimidoyl-6-chloro-5-(ethyl(isopropyl)amino)pyrazine-2-carboxamide 25mg $356.31 2021-12-16 Buy
Alichem 1154252 3-Amino-N-carbamimidoyl-6-chloro-5-(ethyl(isopropyl)amino)pyrazine-2-carboxamide 100mg $899.64 2021-12-16 Buy
Ambeed A367526 3-Amino-N-carbamimidoyl-6-chloro-5-(ethyl(isopropyl)amino)pyrazine-2-carboxamide 98% 25mg $152 2021-12-16 Buy
Ambeed A367526 3-Amino-N-carbamimidoyl-6-chloro-5-(ethyl(isopropyl)amino)pyrazine-2-carboxamide 98% 50mg $245 2021-12-16 Buy
Ambeed A367526 3-Amino-N-carbamimidoyl-6-chloro-5-(ethyl(isopropyl)amino)pyrazine-2-carboxamide 98% 100mg $395 2021-12-16 Buy
American Custom Chemicals Corporation INB0002058 5-(N-ETHYL-N-ISOPROPYL)AMILORIDE 95.00% 5MG $168.3 2021-12-16 Buy
American Custom Chemicals Corporation INB0002058 5-(N-ETHYL-N-ISOPROPYL)AMILORIDE 95.00% 25MG $704.55 2021-12-16 Buy
American Custom Chemicals Corporation INB0002058 5-(N-ETHYL-N-ISOPROPYL)AMILORIDE 95.00% 250MG $1593.9 2021-12-16 Buy
ApexBio Technology B7389 EIPA 5mg $62 2021-12-16 Buy
ApexBio Technology B7389 EIPA 10mg $119 2021-12-16 Buy
ApexBio Technology B7389 EIPA 25mg $203 2021-12-16 Buy
Cayman Chemical 14406 5-(N-ethyl-N-isopropyl)-Amiloride ≥98% 5mg $57 2024-03-01 Buy
Cayman Chemical 14406 5-(N-ethyl-N-isopropyl)-Amiloride ≥98% 10mg $107 2024-03-01 Buy
Cayman Chemical 14406 5-(N-ethyl-N-isopropyl)-Amiloride ≥98% 25mg $179 2024-03-01 Buy

Properties

Melting point :202-205 °C(lit.)
Density :1.49±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :Acetonitrile (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
pka :8.67±0.46(Predicted)
form :Off-white to yellow solid.
color :Pale Yellow to Green
Stability :Unstable in methanol
CAS DataBase Reference :1154-25-2

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Sodium-hydrogen exchangers (NHE) are involved in maintaining sodium and pH balance in a variety of tissues. They are also known as sodium-hydrogen antiporters and solute carrier family 9 members. 5-(N-ethyl-N-isopropyl)-Amiloride (EIPA) is a potent inhibitor of several NHE isoforms, inhibiting NHE1, NHE2, NHE3, and NHE5 with Ki values of 0.02, 0.5, 2.4, and 0.42 μM, respectively. It less effectively inhibits NHE4 (IC50 ≥10 μM). EIPA is commonly used at a concentration of 5-10 μM to inhibit cellular HNE activity.

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