EPTAPIRONE
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- $37 - $3600
- Product name: EPTAPIRONE
- CAS: 179756-58-2
- MF: C16H23N7O2
- MW: 345.4
- EINECS:
- MDL Number:MFCD08690608
- Synonyms:EPTAPIRONE;4-methyl-2-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-1,2,4-triazine-3,5(2H,4H)-dione;F 11440;4-Methyl-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-1,2,4-triazine-3,5(2H,4H)-dione;F-11440;F11440;1,2,4-Triazine-3,5(2H,4H)-dione, 4-methyl-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-;Eptapirone(F11440);Serotonin Receptor,5-HT Receptor,Eptapirone,inhibit,F-11440,5-hydroxytryptamine Receptor,Inhibitor,F11440
17 prices
Selected condition：
Brand
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 250mg
- 1g
- ManufacturerAmbeed
- Product numberA113567
- Product descriptionF11440 98+%
- Packaging5mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113567
- Product descriptionF11440 98+%
- Packaging10mg
- Price$114
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113567
- Product descriptionF11440 98+%
- Packaging25mg
- Price$193
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113567
- Product descriptionF11440 98+%
- Packaging50mg
- Price$251
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113567
- Product descriptionF11440 98+%
- Packaging1g
- Price$3600
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0002409
- Product descriptionEPTAPIRONE 95.00%
- Packaging5MG
- Price$499.81
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS436283
- Product descriptionF11440 ≥98%
- Packaging25mg
- Price$191
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number23449
- Product descriptionEptapirone ≥98%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23449
- Product descriptionEptapirone ≥98%
- Packaging5mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23449
- Product descriptionEptapirone ≥98%
- Packaging10mg
- Price$301
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23449
- Product descriptionEptapirone ≥98%
- Packaging25mg
- Price$618
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5539
- Product descriptionEptapirone 99.91%
- Packaging5mg
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5539
- Product descriptionEptapirone 99.91%
- Packaging10mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5539
- Product descriptionEptapirone 99.91%
- Packaging50mg
- Price$635
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9260
- Product descriptionEptapirone >98%
- Packaging250mg
- Price$800
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9260
- Product descriptionEptapirone >98%
- Packaging1g
- Price$1700
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Ambeed | A113567 | F11440 98+% | 5mg | $68 | 2021-12-16 | Buy |
| Ambeed | A113567 | F11440 98+% | 10mg | $114 | 2021-12-16 | Buy |
| Ambeed | A113567 | F11440 98+% | 25mg | $193 | 2021-12-16 | Buy |
| Ambeed | A113567 | F11440 98+% | 50mg | $251 | 2021-12-16 | Buy |
| Ambeed | A113567 | F11440 98+% | 1g | $3600 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0002409 | EPTAPIRONE 95.00% | 5MG | $499.81 | 2021-12-16 | Buy |
| Arctom | AS436283 | F11440 ≥98% | 25mg | $191 | 2021-12-16 | Buy |
| Cayman Chemical | 23449 | Eptapirone ≥98% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 23449 | Eptapirone ≥98% | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 23449 | Eptapirone ≥98% | 10mg | $301 | 2024-03-01 | Buy |
| Cayman Chemical | 23449 | Eptapirone ≥98% | 25mg | $618 | 2024-03-01 | Buy |
| ChemScene | CS-5539 | Eptapirone 99.91% | 5mg | $105 | 2021-12-16 | Buy |
| ChemScene | CS-5539 | Eptapirone 99.91% | 10mg | $175 | 2021-12-16 | Buy |
| ChemScene | CS-5539 | Eptapirone 99.91% | 50mg | $635 | 2021-12-16 | Buy |
| DC Chemicals | DC9260 | Eptapirone >98% | 250mg | $800 | 2021-12-16 | Buy |
| DC Chemicals | DC9260 | Eptapirone >98% | 1g | $1700 | 2021-12-16 | Buy |
Properties
Boiling point :517.4±60.0 °C(Predicted)
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMF:10.0(Max Conc. mg/mL);28.95(Max Conc. mM)
form :A crystalline solid
pka :7.72±0.10(Predicted)
color :White to off-white
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMF:10.0(Max Conc. mg/mL);28.95(Max Conc. mM)
form :A crystalline solid
pka :7.72±0.10(Predicted)
color :White to off-white
Safety Information
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Description
Eptapirone is a potent agonist of the serotonin (5-HT) receptor subtype 5-HT1A (Ki = 4.8 nM in a radioligand binding assay). It is selective for 5-HT1A over other 5-HT receptor subtypes, dopamine D2 receptors, α1-adrenergic receptors, and histamine H1 receptors (Kis = <10,000, 1,770, 691.8, and <10,000 nM, respectively). Eptapirone inhibits cAMP stimulation induced by forskolin in HA7 cells transfected with human 5-HT1A receptors (EC50 = 158 nM). In vivo, eptapirone increases extracellular 5-HT in the ventral hippocampus of rats (ED50 = 0.049 mg/kg) and serum corticosterone levels when administered p.o. or i.p. (ED50s = 0.16 and 0.057 mg/kg, respectively). It decreases immobility in rats in a forced swim test and increases punished responding in a pigeon conflict procedure, demonstrating antidepressant-like and anxiolytic activity. Eptapirone (2.5 mg/kg, p.o.) also attenuates hypertension and tachycardia induced by sibutramine in rats with no effect on sibutramine-induced hypophagia.More related product prices
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