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ChemicalBook >> CAS DataBase List >> ERDAFITINIB

ERDAFITINIB

ERDAFITINIB price.
  • $31 - $1400
  • Product name: ERDAFITINIB
  • CAS: 1346242-81-6
  • MF: C25H30N6O2
  • MW: 446.54
  • EINECS:
  • MDL Number:MFCD28502040
  • Synonyms:Erdafitinib;Erdafitinib(JNJ-42756493);N-(3,5-dimethoxyphenyl)-N'-(1-methylethyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine;N1-(3,5-Dimethoxyphenyl)-N2-(1-methylethyl)-N1-[3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl]-1,2-ethanediamine;Suftalan Zine;N-(3,5-Dimethoxyphenyl)-N'-isopropyl-N-[3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl]-1,2-ethanediamine;N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine;ERDAFITINIB;JNJ-42756493 ;JNJ 42756493 ;JNJ42756493
19 prices
Selected condition:
Brand
  • AK Scientific
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAK Scientific
  • Product number9849BB
  • Product descriptionErdafitinib
  • Packaging100mg
  • Price$414
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFE76167
  • Product descriptionErdafitinib
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFE76167
  • Product descriptionErdafitinib
  • Packaging50mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFE76167
  • Product descriptionErdafitinib
  • Packaging100mg
  • Price$270
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFE76167
  • Product descriptionErdafitinib
  • Packaging250mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFE76167
  • Product descriptionErdafitinib
  • Packaging500mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21813
  • Product descriptionJNJ-42756493 ≥98%
  • Packaging1mg
  • Price$31
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21813
  • Product descriptionJNJ-42756493 ≥98%
  • Packaging5mg
  • Price$85
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21813
  • Product descriptionJNJ-42756493 ≥98%
  • Packaging10mg
  • Price$138
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21813
  • Product descriptionJNJ-42756493 ≥98%
  • Packaging25mg
  • Price$269
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM142040
  • Product descriptionN1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine 98%
  • Packaging100mg
  • Price$982
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4988
  • Product descriptionErdafitinib 99.66%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4988
  • Product descriptionErdafitinib 99.66%
  • Packaging10mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4988
  • Product descriptionErdafitinib 99.66%
  • Packaging50mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4988
  • Product descriptionErdafitinib 99.66%
  • Packaging100mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003806
  • Product descriptionErdafitinib 98+%
  • Packaging50mg
  • Price$311
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9849BB Erdafitinib 100mg $414 2021-12-16 Buy
Biosynth Carbosynth FE76167 Erdafitinib 10mg $70 2021-12-16 Buy
Biosynth Carbosynth FE76167 Erdafitinib 50mg $170 2021-12-16 Buy
Biosynth Carbosynth FE76167 Erdafitinib 100mg $270 2021-12-16 Buy
Biosynth Carbosynth FE76167 Erdafitinib 250mg $400 2021-12-16 Buy
Biosynth Carbosynth FE76167 Erdafitinib 500mg $650 2021-12-16 Buy
Cayman Chemical 21813 JNJ-42756493 ≥98% 1mg $31 2024-03-01 Buy
Cayman Chemical 21813 JNJ-42756493 ≥98% 5mg $85 2024-03-01 Buy
Cayman Chemical 21813 JNJ-42756493 ≥98% 10mg $138 2024-03-01 Buy
Cayman Chemical 21813 JNJ-42756493 ≥98% 25mg $269 2024-03-01 Buy
Chemenu CM142040 N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine 98% 100mg $982 2021-12-16 Buy
ChemScene CS-4988 Erdafitinib 99.66% 5mg $50 2021-12-16 Buy
ChemScene CS-4988 Erdafitinib 99.66% 10mg $80 2021-12-16 Buy
ChemScene CS-4988 Erdafitinib 99.66% 50mg $190 2021-12-16 Buy
ChemScene CS-4988 Erdafitinib 99.66% 100mg $290 2021-12-16 Buy
Crysdot CD31003806 Erdafitinib 98+% 50mg $311 2021-12-16 Buy

Properties

Melting point :136-140°C
Boiling point :662.3±55.0 °C(Predicted)
Density :1.20±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :9.45±0.29(Predicted)
color :Yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P310 Immediately call a POISON CENTER or doctor/physician.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Erdafitinib is an oral pan-FGFR (1-4) inhibitor with has demonstrated promising activity in patients with metastatic or unresectable UC and other histologies (eg, cholangiocarcinoma) with FGFR alterations. It is used in the therapy of locally advanced, unresectable or metastatic urothelial carcinoma. Erdafitinib has been associated with a high rate of serum enzyme elevations during therapy, but has not been linked to cases of clinically apparent acute liver injury.