Eflornithine

$605.17
Product name: Eflornithine
CAS: 67037-37-0
MF: C6H12F2N2O2
MW: 182.17
EINECS:
MDL Number:MFCD00221766
Synonyms:D,L-2-DIFLUOROMETHYLORNITHINE;H-DL-(A-DIFLUOROMETHYL)ORN-OH;Eflornithine base;Ornidyl;Eflornithine;2-(Difluoromethyl)ornithine;2,5-bis(azanyl)-2-(difluoromethyl)pentanoic acid;2,5-diamino-2-(difluoromethyl)valeric acid

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Brand

American Custom Chemicals Corporation

Package

10MG

ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0002526
Product descriptionEFLORNITHINE 95.00%
Packaging10MG
Price$605.17
Updated2021-12-16
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Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	API0002526	EFLORNITHINE 95.00%	10MG	$605.17	2021-12-16	Buy

Properties

Density :1.1800 (estimate)
storage temp. :-15°C

Safety Information

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Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes

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Description

Metcalf et al.reported the synthesis of eflornithine (difluoromethyl ornithine [DFMO]) in 1978. Their interest arose from the desire to prepare ornithine decarboxylase (ODC) inhibitors as tools for studying the role of polyamines as regulators of growth processes. Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine (1,4-diaminobutane), which in turn leads to the formation of the polyamines, spermine, and spermidine. It was not until 1980 that Bacchi et al. demonstrated the potential of DFMO in the treatment of trypanosomiasis.

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