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ChemicalBook >> CAS DataBase List >> Eliglustat hemitartrate

Eliglustat hemitartrate

Eliglustat hemitartrate price.
  • $32 - $1042
  • Product name: Eliglustat hemitartrate
  • CAS: 928659-70-5
  • MF: C50H78N4O14
  • MW: 959.17272
  • EINECS:
  • MDL Number:MFCD22665712
  • Synonyms:Eliglustat (Tartrate);Eliglustat (hemitartrate);Eliglustat hemitartrate(Genz-99067);GENZ112638;(2R,3R)-2,3-Dihydroxysuccinic acid - N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamide (1:2);N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide,(2R,3R)-2,3-dihydroxybutanedioic Acid;Eliglustat hemitartrate (Genz-112638);GENZ-99067;GENZ99067;GENZ 99067;GENZ-112638;GENZ112638;GENZ 112638;ELIGLUSTAT TARTRATE
11 prices
Selected condition:
Brand
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerCayman Chemical
  • Product number21487
  • Product descriptionEliglustat (hemitartrate) ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21487
  • Product descriptionEliglustat (hemitartrate) ≥98%
  • Packaging5mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21487
  • Product descriptionEliglustat (hemitartrate) ≥98%
  • Packaging10mg
  • Price$243
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21487
  • Product descriptionEliglustat (hemitartrate) ≥98%
  • Packaging25mg
  • Price$533
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000219
  • Product descriptionEliglustattartrate 98+%
  • Packaging5mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000219
  • Product descriptionEliglustattartrate 98+%
  • Packaging10mg
  • Price$277
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000219
  • Product descriptionEliglustattartrate 98+%
  • Packaging50mg
  • Price$743
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000219
  • Product descriptionEliglustattartrate 98+%
  • Packaging100mg
  • Price$1042
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9291
  • Product descriptionEliglustathemitartrate(Genz-112638) >98%
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberE508025
  • Product descriptionEliglustatTartrate
  • Packaging50mg
  • Price$760
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number448126
  • Product descriptionEliglustat Tartrate
  • Packaging1mg
  • Price$305
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 21487 Eliglustat (hemitartrate) ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 21487 Eliglustat (hemitartrate) ≥98% 5mg $139 2024-03-01 Buy
Cayman Chemical 21487 Eliglustat (hemitartrate) ≥98% 10mg $243 2024-03-01 Buy
Cayman Chemical 21487 Eliglustat (hemitartrate) ≥98% 25mg $533 2024-03-01 Buy
Crysdot CD31000219 Eliglustattartrate 98+% 5mg $149 2021-12-16 Buy
Crysdot CD31000219 Eliglustattartrate 98+% 10mg $277 2021-12-16 Buy
Crysdot CD31000219 Eliglustattartrate 98+% 50mg $743 2021-12-16 Buy
Crysdot CD31000219 Eliglustattartrate 98+% 100mg $1042 2021-12-16 Buy
DC Chemicals DC9291 Eliglustathemitartrate(Genz-112638) >98% 100mg $450 2021-12-16 Buy
TRC E508025 EliglustatTartrate 50mg $760 2021-12-16 Buy
Usbiological 448126 Eliglustat Tartrate 1mg $305 2021-12-16 Buy

Properties

Melting point :>133°C (dec.)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White
InChIKey :KUBARPMUNHKBIQ-VTHUDJRQSA-N

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Eliglustat tartrate, developed and marketed by Genzyme Corporation (a subsidiary of Sanofi), was approved by the US FDA in August 2014 for the treatment of nonneuropathic (type 1) Gaucher disease (GD1) in both treatment-naive and treatment-experienced adult patients. It is the first oral treatment to be approved for first-line use in patients with Gaucher disease type 1, which is a rare lysosomal storage disease characterized by accumulation of lipid glucosylceramide (GL-1) due to insufficient production of the enzyme glucosylceramidase. Clinical complications include hepatosplenomegaly, anemia, thrombocytopenia, and bone involvement. Eliglustat is a specific inhibitor of glucosylceramide synthase with an IC50 of 10 ng/mL and acts as substrate reduction therapy for GD1; it has demonstrated non-inferiority to enzyme replacement therapy, which is the current standard of care, in Phase III trials.

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