Eliglustat hemitartrate
- $32 - $1042
- Product name: Eliglustat hemitartrate
- CAS: 928659-70-5
- MF: C50H78N4O14
- MW: 959.17272
- EINECS:
- MDL Number:MFCD22665712
- Synonyms:Eliglustat (Tartrate);Eliglustat (hemitartrate);Eliglustat hemitartrate(Genz-99067);GENZ112638;(2R,3R)-2,3-Dihydroxysuccinic acid - N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamide (1:2);N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide,(2R,3R)-2,3-dihydroxybutanedioic Acid;Eliglustat hemitartrate (Genz-112638);GENZ-99067;GENZ99067;GENZ 99067;GENZ-112638;GENZ112638;GENZ 112638;ELIGLUSTAT TARTRATE
11 prices
Selected condition:
Brand
- Cayman Chemical
- Crysdot
- DC Chemicals
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- ManufacturerCayman Chemical
- Product number21487
- Product descriptionEliglustat (hemitartrate) ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21487
- Product descriptionEliglustat (hemitartrate) ≥98%
- Packaging5mg
- Price$139
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21487
- Product descriptionEliglustat (hemitartrate) ≥98%
- Packaging10mg
- Price$243
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21487
- Product descriptionEliglustat (hemitartrate) ≥98%
- Packaging25mg
- Price$533
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31000219
- Product descriptionEliglustattartrate 98+%
- Packaging5mg
- Price$149
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000219
- Product descriptionEliglustattartrate 98+%
- Packaging10mg
- Price$277
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000219
- Product descriptionEliglustattartrate 98+%
- Packaging50mg
- Price$743
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000219
- Product descriptionEliglustattartrate 98+%
- Packaging100mg
- Price$1042
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9291
- Product descriptionEliglustathemitartrate(Genz-112638) >98%
- Packaging100mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberE508025
- Product descriptionEliglustatTartrate
- Packaging50mg
- Price$760
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number448126
- Product descriptionEliglustat Tartrate
- Packaging1mg
- Price$305
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Cayman Chemical | 21487 | Eliglustat (hemitartrate) ≥98% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 21487 | Eliglustat (hemitartrate) ≥98% | 5mg | $139 | 2024-03-01 | Buy |
Cayman Chemical | 21487 | Eliglustat (hemitartrate) ≥98% | 10mg | $243 | 2024-03-01 | Buy |
Cayman Chemical | 21487 | Eliglustat (hemitartrate) ≥98% | 25mg | $533 | 2024-03-01 | Buy |
Crysdot | CD31000219 | Eliglustattartrate 98+% | 5mg | $149 | 2021-12-16 | Buy |
Crysdot | CD31000219 | Eliglustattartrate 98+% | 10mg | $277 | 2021-12-16 | Buy |
Crysdot | CD31000219 | Eliglustattartrate 98+% | 50mg | $743 | 2021-12-16 | Buy |
Crysdot | CD31000219 | Eliglustattartrate 98+% | 100mg | $1042 | 2021-12-16 | Buy |
DC Chemicals | DC9291 | Eliglustathemitartrate(Genz-112638) >98% | 100mg | $450 | 2021-12-16 | Buy |
TRC | E508025 | EliglustatTartrate | 50mg | $760 | 2021-12-16 | Buy |
Usbiological | 448126 | Eliglustat Tartrate | 1mg | $305 | 2021-12-16 | Buy |
Properties
Melting point :>133°C (dec.)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White
InChIKey :KUBARPMUNHKBIQ-VTHUDJRQSA-N
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White
InChIKey :KUBARPMUNHKBIQ-VTHUDJRQSA-N
Safety Information
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Description
Eliglustat tartrate, developed and marketed by Genzyme Corporation (a subsidiary of Sanofi), was approved by the US FDA in August 2014 for the treatment of nonneuropathic (type 1) Gaucher disease (GD1) in both treatment-naive and treatment-experienced adult patients. It is the first oral treatment to be approved for first-line use in patients with Gaucher disease type 1, which is a rare lysosomal storage disease characterized by accumulation of lipid glucosylceramide (GL-1) due to insufficient production of the enzyme glucosylceramidase. Clinical complications include hepatosplenomegaly, anemia, thrombocytopenia, and bone involvement. Eliglustat is a specific inhibitor of glucosylceramide synthase with an IC50 of 10 ng/mL and acts as substrate reduction therapy for GD1; it has demonstrated non-inferiority to enzyme replacement therapy, which is the current standard of care, in Phase III trials.More related product prices
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