Epothilone B
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- $50 - $18416
- Product name: Epothilone B
- CAS: 152044-54-7
- MF: C27H41NO6S
- MW: 507.68
- EINECS:604-822-6
- MDL Number:MFCD02101921
- Synonyms:Epothilone B(EPO906);Epothilone B HOUSE STANDARD;Epothilone B(Patupilone);(3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentaMethyl-3-((E)-1-(2-Methylthiazol-4-yl)prop-1-en-2-yl)-4,17-dioxa-bicyclo[14.1.0]heptadecan-5,9-dione;Epothilone B (EPO906, Patupilone);EPOTHILONE;(1S,3S,7S,10R,11S,12S,16R,E)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-(1-(2-methylthiazol-4-yl)prop-1-en-2-yl)-4,17-dioxa-bicyclo[14.1.0]heptadecane-5,9-dione;Patupilone (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
36 prices
Selected condition:
Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 10mM(in 1mL DMSO)
- 100ug
- 0.1MG
- 1MG
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- 10g
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005272
- Product descriptionPATUPILONE 95.00%
- Packaging0.1MG
- Price$406
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005272
- Product descriptionPATUPILONE 95.00%
- Packaging1MG
- Price$460
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1630
- Product descriptionEpothiloneB(EPO906,Patupilone)
- Packaging10mM(in 1mL DMSO)
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3099
- Product descriptionEpothilone B
- Packaging5mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3099
- Product descriptionEpothilone B
- Packaging10mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3099
- Product descriptionEpothilone B
- Packaging25mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545992
- Product descriptionEpothilone B >98%
- Packaging1mg
- Price$154.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545992
- Product descriptionEpothilone B >98%
- Packaging5mg
- Price$357
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154682
- Product descriptionEpothilone B >99%
- Packaging100mg
- Price$912.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154682
- Product descriptionEpothilone B >99%
- Packaging250mg
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154682
- Product descriptionEpothilone B >99%
- Packaging1g
- Price$3728.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10924
- Product descriptionEpothilone B ≥95%
- Packaging1mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10924
- Product descriptionEpothilone B ≥95%
- Packaging5mg
- Price$481
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10924
- Product descriptionEpothilone B ≥95%
- Packaging10mg
- Price$856
- Updated2024-03-01
- Buy
- ManufacturerChem-Impex
- Product number37869
- Product descriptionEpothiloneB,≥95%(HPLC) ≥95%(HPLC)
- Packaging25MG
- Price$488.05
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0714
- Product descriptionEpothilone B 99.88%
- Packaging2mg
- Price$50
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
American Custom Chemicals Corporation | API0005272 | PATUPILONE 95.00% | 0.1MG | $406 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0005272 | PATUPILONE 95.00% | 1MG | $460 | 2021-12-16 | Buy |
ApexBio Technology | A1630 | EpothiloneB(EPO906,Patupilone) | 10mM(in 1mL DMSO) | $80 | 2021-12-16 | Buy |
AvaChem | 3099 | Epothilone B | 5mg | $65 | 2021-12-16 | Buy |
AvaChem | 3099 | Epothilone B | 10mg | $110 | 2021-12-16 | Buy |
AvaChem | 3099 | Epothilone B | 25mg | $225 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545992 | Epothilone B >98% | 1mg | $154.7 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545992 | Epothilone B >98% | 5mg | $357 | 2021-12-16 | Buy |
Biorbyt Ltd | orb154682 | Epothilone B >99% | 100mg | $912.9 | 2021-12-16 | Buy |
Biorbyt Ltd | orb154682 | Epothilone B >99% | 250mg | $1802 | 2021-12-16 | Buy |
Biorbyt Ltd | orb154682 | Epothilone B >99% | 1g | $3728.1 | 2021-12-16 | Buy |
Cayman Chemical | 10924 | Epothilone B ≥95% | 1mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 10924 | Epothilone B ≥95% | 5mg | $481 | 2024-03-01 | Buy |
Cayman Chemical | 10924 | Epothilone B ≥95% | 10mg | $856 | 2024-03-01 | Buy |
Chem-Impex | 37869 | EpothiloneB,≥95%(HPLC) ≥95%(HPLC) | 25MG | $488.05 | 2021-12-16 | Buy |
ChemScene | CS-0714 | Epothilone B 99.88% | 2mg | $50 | 2021-12-16 | Buy |
Properties
Melting point :95-97°C
alpha :D21 -35° (c = 0.7 in methanol)
Boiling point :680.2±55.0 °C(Predicted)
Density :1.136
storage temp. :Store at -20°C
solubility :Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 35 mg/ml).
form :White to off-white solid
pka :13.57±0.70(Predicted)
color :colorless
optical activity :-35.021 (methanol)
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChIKey :QXRSDHAAWVKZLJ-PVYNADRNSA-N
CAS DataBase Reference :152044-54-7
alpha :D21 -35° (c = 0.7 in methanol)
Boiling point :680.2±55.0 °C(Predicted)
Density :1.136
storage temp. :Store at -20°C
solubility :Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 35 mg/ml).
form :White to off-white solid
pka :13.57±0.70(Predicted)
color :colorless
optical activity :-35.021 (methanol)
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChIKey :QXRSDHAAWVKZLJ-PVYNADRNSA-N
CAS DataBase Reference :152044-54-7
Safety Information
Symbol(GHS): |
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Description
Epothilone B (Epo B) is a macrolide that causes the formation of bundles of intracellular microtubules in non-mitotic cells, induces the formation of hyperstable tubulin polymers, and arrests cell cycling in mitosis. It induces mitotic arrest at the G2-M transition in Hs578T and HeLa cells (IC50 = 3 and 32 nM, respectively) as well as in multidrug resistant KB3-1 and KBV-1 cells (IC50 = 16 and 92 nM, respectively). Epo B causes cell cycle arrest at nanomolar IC50 values in cell lines from ovarian, breast, lung, colon, prostate, and squamous cancer.More related product prices
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Suppliers and manufacturers
Shanghai Minbiotech Co., Ltd.
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Hubei Jusheng Technology Co.,Ltd.