Esomeprazole
- $17 - $1208.7
- Product name: Esomeprazole
- CAS: 119141-88-7
- MF: C17H19N3O3S
- MW: 345.42
- EINECS:643-098-6
- MDL Number:MFCD09907604
- Synonyms:EsoMeprazole EC Pellets 22%;EsoMaprozole;1H-BenziMidazole,6-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl]-;EsoMeprazole EC Pellets 8.5%;6-Methoxy-2-{(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl}-1H-benziMidazole;Esomeprazole(Na、Mg);(5-methoxy-1H-benzimidazol-2-yl)[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfoniumolate;(S)-Esomeprazole
23 prices
Selected condition:
Brand
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Biorbyt Ltd
- Chemenu
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
Package
- 1mg
- 5MG
- 50mg
- 100mg
- 250mg
- 1g
- 10g
- 25g
- 100g
- ManufacturerAmbeed
- Product numberA388173
- Product description(S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99%
- Packaging50mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA388173
- Product description(S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99%
- Packaging100mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA388173
- Product description(S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99%
- Packaging250mg
- Price$76
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA388173
- Product description(S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99%
- Packaging1g
- Price$187
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0019511
- Product description(S)-6-METHOXY-2-(((4-METHOXY-3,5-DIMETHYLPYRIDIN-2-YL)METHYL)SULFINYL)-1H-BENZO[D]IMIDAZOLE 95.00%
- Packaging5MG
- Price$501.55
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS542072
- Product description(S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99%
- Packaging1mg
- Price$17
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS542072
- Product description(S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99%
- Packaging5mg
- Price$34
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS542072
- Product description(S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99%
- Packaging100mg
- Price$215
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS542072
- Product description(S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99%
- Packaging250mg
- Price$312
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2660A
- Product descriptionEsomeprazole
- Packaging100mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2660A
- Product descriptionEsomeprazole
- Packaging1g
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2660A
- Product descriptionEsomeprazole
- Packaging10g
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134728
- Product descriptionEsomeprazole >99%
- Packaging100mg
- Price$414.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134728
- Product descriptionEsomeprazole >99%
- Packaging250mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134728
- Product descriptionEsomeprazole >99%
- Packaging1g
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM160492
- Product description(S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 97%
- Packaging25g
- Price$262
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Ambeed | A388173 | (S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99% | 50mg | $39 | 2021-12-16 | Buy |
Ambeed | A388173 | (S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99% | 100mg | $50 | 2021-12-16 | Buy |
Ambeed | A388173 | (S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99% | 250mg | $76 | 2021-12-16 | Buy |
Ambeed | A388173 | (S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99% | 1g | $187 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0019511 | (S)-6-METHOXY-2-(((4-METHOXY-3,5-DIMETHYLPYRIDIN-2-YL)METHYL)SULFINYL)-1H-BENZO[D]IMIDAZOLE 95.00% | 5MG | $501.55 | 2021-12-16 | Buy |
Arctom | AS542072 | (S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99% | 1mg | $17 | 2021-12-16 | Buy |
Arctom | AS542072 | (S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99% | 5mg | $34 | 2021-12-16 | Buy |
Arctom | AS542072 | (S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99% | 100mg | $215 | 2021-12-16 | Buy |
Arctom | AS542072 | (S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 99% | 250mg | $312 | 2021-12-16 | Buy |
AvaChem | 2660A | Esomeprazole | 100mg | $59 | 2021-12-16 | Buy |
AvaChem | 2660A | Esomeprazole | 1g | $119 | 2021-12-16 | Buy |
AvaChem | 2660A | Esomeprazole | 10g | $390 | 2021-12-16 | Buy |
Biorbyt Ltd | orb134728 | Esomeprazole >99% | 100mg | $414.8 | 2021-12-16 | Buy |
Biorbyt Ltd | orb134728 | Esomeprazole >99% | 250mg | $615.4 | 2021-12-16 | Buy |
Biorbyt Ltd | orb134728 | Esomeprazole >99% | 1g | $1208.7 | 2021-12-16 | Buy |
Chemenu | CM160492 | (S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole 97% | 25g | $262 | 2021-12-16 | Buy |
Properties
alpha :D20 -155° (c = 0.5 in chloroform)
Boiling point :600.0±60.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml
form :A solid
pka :8.50±0.10(Predicted)
CAS DataBase Reference :119141-88-7(CAS DataBase Reference)
Boiling point :600.0±60.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml
form :A solid
pka :8.50±0.10(Predicted)
CAS DataBase Reference :119141-88-7(CAS DataBase Reference)
Safety Information
Symbol(GHS): | |||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | ||||||||||||||||||||||||||||||||||||||||||
Hazard statements: |
|
||||||||||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
Esomeprazole, formulated as a magnesium salt, reached the market as a treatment for acid-related diseases such as gastro-esophageal reflux (GERD) disease including peptic ulcer disease and reflux esophagitis. Esomeprazole (formerly perprazole) is the active (S)- enantiomer of omeprazole (1988) and the first proton pump inhibitor developed as an optical isomer. It can be obtained by several routes such as asymmetric oxidation of the pro-chiral pyridylmethyl benzimidazole sulfide, separation from the racemic sulfoxide by chiral chromatography or separation of a diastereomeric mixture obtained from the racemic compound and a chiral acid, followed by hydrolysis. Biochemical studies have shown that esomeprazole irreversibly inhibits the gastric H+/K+-adenosine triphosphatase (ATPase), an enzyme system involved at the secretory surface of the stomach’s parietal cells responsible for the secretion of gastric acid. Compared with racemic omeprazole in healthy subjects, esomeprazole has higher bioavailability, is absorbed more rapidly and exhibits a more uniform and predictable dose-response with higher plasma levels, leading to less inter-individual variability between slow and rapid metabolizers. In extensive clinical trials in patients suffering from GERD symptoms, esomeprazole provided superior acid control and significantly reduced the healing time compared to omeprazole.More related product prices
Dimethyl fumarate Dimethyl sulfoxide Dimethyl disulfide Dacthal Benzimidazole (Trifluoromethoxy)benzene 2,6-Lutidine Dimethyl ether Omeprazole Dimethyl sulfate Phenformin Dimethyl carbonate ETHANE N,N-Dimethylformamide Esomeprazole Lansoprazole Pantoprazole R-(+)-LansoprazoleRelated product price
- Dimethyl fumarate
$5-685.21 - Dimethyl sulfoxide
$15-120900 - Dimethyl disulfide
$27.9-1330
Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Henan Tianfu Chemical Co.,Ltd.