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ChemicalBook >> CAS DataBase List >> FBPase-1 Inhibitor

FBPase-1 Inhibitor

FBPase-1 Inhibitor price.
  • $39 - $705
  • Product name: FBPase-1 Inhibitor
  • CAS: 883973-99-7
  • MF: C13H7Cl3N2O3S
  • MW: 377.63
  • EINECS:-0
  • MDL Number:
  • Synonyms:FBPase-1 Inhibitor;Fructose 1,6-bisphosphatase-1 Inhibitor;Benzenesulfonamide, 2,5-dichloro-N-(5-chloro-2-benzoxazolyl)-;FBPase-1 inhibitor-1;2,5-Dichloro-N-(5-chlorobenzo[d]oxazol-2-yl)benzenesulfonamide;Fructose-1;FBPase,inhibit,FBPase 1 inhibitor 1,FBPase1 inhibitor1,Inhibitor;2,5-dichloro-N-(5-chloro-2-benzoxazolyl)-benzenesulfonamide
Price16 Properties Safety Information Description
16 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number6300CP
  • Product description2,5-Dichloro-N-(5-chloro-1,3-benzoxazol-2-YL)benzenesulfonamide
  • Packaging1mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ65298
  • Product descriptionFBPase-1 Inhibitor
  • Packaging10mg
  • Price$121
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ65298
  • Product descriptionFBPase-1 Inhibitor
  • Packaging50mg
  • Price$501
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1209735
  • Product description2,5-Dichloro-N-(5-chlorobenzo[d]oxazol-2-yl)benzenesulfonamide 98+%
  • Packaging10mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1209735
  • Product description2,5-Dichloro-N-(5-chlorobenzo[d]oxazol-2-yl)benzenesulfonamide 98+%
  • Packaging25mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1209735
  • Product description2,5-Dichloro-N-(5-chlorobenzo[d]oxazol-2-yl)benzenesulfonamide 98+%
  • Packaging50mg
  • Price$106
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1209735
  • Product description2,5-Dichloro-N-(5-chlorobenzo[d]oxazol-2-yl)benzenesulfonamide 98+%
  • Packaging100mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3549
  • Product descriptionFructose1,6-bisphosphatase-1Inhibitor
  • Packaging5mg
  • Price$123
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3549
  • Product descriptionFructose1,6-bisphosphatase-1Inhibitor
  • Packaging10mg
  • Price$194
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3549
  • Product descriptionFructose1,6-bisphosphatase-1Inhibitor
  • Packaging50mg
  • Price$705
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon3439
  • Product descriptionFBPase-1inhibitor-FBPase-1inhibitorcompound1 99%
  • Packaging50mg
  • Price$396
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18860
  • Product descriptionFructose 1,6-bisphosphatase-1 Inhibitor ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18860
  • Product descriptionFructose 1,6-bisphosphatase-1 Inhibitor ≥98%
  • Packaging5mg
  • Price$118
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18860
  • Product descriptionFructose 1,6-bisphosphatase-1 Inhibitor ≥98%
  • Packaging10mg
  • Price$151
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18860
  • Product descriptionFructose 1,6-bisphosphatase-1 Inhibitor ≥98%
  • Packaging50mg
  • Price$638
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberF792450
  • Product descriptionFBPase-1 Inhibitor
  • Packaging5mg
  • Price$85
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6300CP 2,5-Dichloro-N-(5-chloro-1,3-benzoxazol-2-YL)benzenesulfonamide 1mg $147 2021-12-16 Buy
Alfa Aesar J65298 FBPase-1 Inhibitor 10mg $121 2021-12-16 Buy
Alfa Aesar J65298 FBPase-1 Inhibitor 50mg $501 2021-12-16 Buy
Ambeed A1209735 2,5-Dichloro-N-(5-chlorobenzo[d]oxazol-2-yl)benzenesulfonamide 98+% 10mg $39 2021-12-16 Buy
Ambeed A1209735 2,5-Dichloro-N-(5-chlorobenzo[d]oxazol-2-yl)benzenesulfonamide 98+% 25mg $66 2021-12-16 Buy
Ambeed A1209735 2,5-Dichloro-N-(5-chlorobenzo[d]oxazol-2-yl)benzenesulfonamide 98+% 50mg $106 2021-12-16 Buy
Ambeed A1209735 2,5-Dichloro-N-(5-chlorobenzo[d]oxazol-2-yl)benzenesulfonamide 98+% 100mg $170 2021-12-16 Buy
ApexBio Technology C3549 Fructose1,6-bisphosphatase-1Inhibitor 5mg $123 2021-12-16 Buy
ApexBio Technology C3549 Fructose1,6-bisphosphatase-1Inhibitor 10mg $194 2021-12-16 Buy
ApexBio Technology C3549 Fructose1,6-bisphosphatase-1Inhibitor 50mg $705 2021-12-16 Buy
Axon Medchem Axon3439 FBPase-1inhibitor-FBPase-1inhibitorcompound1 99% 50mg $396 2021-12-16 Buy
Cayman Chemical 18860 Fructose 1,6-bisphosphatase-1 Inhibitor ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 18860 Fructose 1,6-bisphosphatase-1 Inhibitor ≥98% 5mg $118 2024-03-01 Buy
Cayman Chemical 18860 Fructose 1,6-bisphosphatase-1 Inhibitor ≥98% 10mg $151 2024-03-01 Buy
Cayman Chemical 18860 Fructose 1,6-bisphosphatase-1 Inhibitor ≥98% 50mg $638 2024-03-01 Buy
TRC F792450 FBPase-1 Inhibitor 5mg $85 2021-12-16 Buy

Properties

Boiling point :536.5±60.0 °C(Predicted)
Density :1.681±0.06 g/cm3(Predicted)
solubility :Soluble in DMSO
pka :5.85±0.30(Predicted)
form :Solid
color :White to off-white
Sensitive :Light Sensitive

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Fructose 1,6-bisphosphatase-1 (FBPase-1) is an enzyme that catalyzes the conversion of fructose-1,6-bisphosphate to fructose 6-phosphate, which is one of the rate-limiting steps in gluconeogenesis. Excess hepatic FBPase-1 activity contributes to hyperglycemia in patients. Thus, the development of specific FBPase-1 inhibitors is of great clinical interest for the treatment of patients with type 2 diabetes. FBPase-1 inhibitor is a cell-permeable benzoxazolo-sulfonamide compound that blocks human FBPase-1 enzymatic activity with an IC50 value of 3.4 μM (Ki = 1.1 μM) by competing at the AMP allosteric binding site. It has been shown to block glucose production in rat hepatoma cells that are starved of nutrients with an IC50 value of 6.6 μM.

Suppliers and manufacturers

TargetMol Chemicals Inc.
FBPase-1 inhibitor-1
$52.00 /5mg
FBPase-1 inhibitor-1 CAS:883973-99-7
InvivoChem
Aladdin Scientific VDM Biochemicals BOC Sciences Shanghai EFE Biological Technology Co., Ltd. Tianjin Kailiqi Biotechnology Co., Ltd. Shanghai SuperLan Chemcial Technique Centre Henan Alpha Chemical Co., Ltd. Jinan ponder chemical co. LTD