FIIN-3
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- $37 - $2220
- Product name: FIIN-3
- CAS: 1637735-84-2
- MF: C34H36Cl2N8O4
- MW: 691.61
- EINECS:
- MDL Number:MFCD28386554
- Synonyms:FIIN-3;FIN-3;FIIN3; FIIN 3;FIIN3; FIIN 3; FIIN-3;CS-2331;2-Propenamide, N-[4-[[[[(2,6-dichloro-3,5-dimethoxyphenyl)amino]carbonyl][6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]methyl]phenyl]-;Inhibitor,FIIN 3,FIIN-3,HER1,FIIN3,ErbB-1,Epidermal growth factor receptor,inhibit,Fibroblast growth factor receptor,EGFR,FGFR
14 prices
Selected condition:
Brand
- AK Scientific
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number7571DW
- Product descriptionN-[4-[[(2,6-Dichloro-3,5-dimethoxyphenyl)carbamoyl-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide
- Packaging1mg
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number20709
- Product descriptionFIIN-3 ≥98%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20709
- Product descriptionFIIN-3 ≥98%
- Packaging5mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20709
- Product descriptionFIIN-3 ≥98%
- Packaging10mg
- Price$283
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20709
- Product descriptionFIIN-3 ≥98%
- Packaging25mg
- Price$618
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5514
- Product descriptionFIIN-3 98.13%
- Packaging1mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5514
- Product descriptionFIIN-3 98.13%
- Packaging5mg
- Price$264
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5514
- Product descriptionFIIN-3 98.13%
- Packaging10mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5514
- Product descriptionFIIN-3 98.13%
- Packaging50mg
- Price$1440
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5514
- Product descriptionFIIN-3 98.13%
- Packaging100mg
- Price$2220
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9642
- Product descriptionFIIN-3 >98%
- Packaging100mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9642
- Product descriptionFIIN-3 >98%
- Packaging250mg
- Price$900
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9642
- Product descriptionFIIN-3 >98%
- Packaging1g
- Price$1800
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberF336510
- Product descriptionFIIN-3
- Packaging1mg
- Price$145
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 7571DW | N-[4-[[(2,6-Dichloro-3,5-dimethoxyphenyl)carbamoyl-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide | 1mg | $139 | 2021-12-16 | Buy |
Cayman Chemical | 20709 | FIIN-3 ≥98% | 1mg | $37 | 2024-03-01 | Buy |
Cayman Chemical | 20709 | FIIN-3 ≥98% | 5mg | $161 | 2024-03-01 | Buy |
Cayman Chemical | 20709 | FIIN-3 ≥98% | 10mg | $283 | 2024-03-01 | Buy |
Cayman Chemical | 20709 | FIIN-3 ≥98% | 25mg | $618 | 2024-03-01 | Buy |
ChemScene | CS-5514 | FIIN-3 98.13% | 1mg | $108 | 2021-12-16 | Buy |
ChemScene | CS-5514 | FIIN-3 98.13% | 5mg | $264 | 2021-12-16 | Buy |
ChemScene | CS-5514 | FIIN-3 98.13% | 10mg | $420 | 2021-12-16 | Buy |
ChemScene | CS-5514 | FIIN-3 98.13% | 50mg | $1440 | 2021-12-16 | Buy |
ChemScene | CS-5514 | FIIN-3 98.13% | 100mg | $2220 | 2021-12-16 | Buy |
DC Chemicals | DC9642 | FIIN-3 >98% | 100mg | $500 | 2021-12-16 | Buy |
DC Chemicals | DC9642 | FIIN-3 >98% | 250mg | $900 | 2021-12-16 | Buy |
DC Chemicals | DC9642 | FIIN-3 >98% | 1g | $1800 | 2021-12-16 | Buy |
TRC | F336510 | FIIN-3 | 1mg | $145 | 2021-12-16 | Buy |
Properties
Boiling point :909.4±65.0 °C(Predicted)
Density :1.379±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Acetonitrile: sparingly soluble; Methanol: sparingly soluble
form :A crystalline solid
pka :10.78±0.70(Predicted)
Density :1.379±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Acetonitrile: sparingly soluble; Methanol: sparingly soluble
form :A crystalline solid
pka :10.78±0.70(Predicted)
Safety Information
Symbol(GHS): |
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Description
FIIN-3 is an inhibitor of FGF receptors (FGFRs; IC50s = 13, 21, 31, and 35 nM for recombinant FGFR1-4, respectively). It is selective for FGFRs over a panel of 456 kinases at a concentration of 1 μM, however, it does inhibit EGFR (IC50 = 204 nM). FIIN-3 inhibits growth of Ba/F3 cells that are dependent on the kinase activity of wild-type FGFR1-4 as well as gatekeeper mutant FGFR2 and FGFR3 (EC50s = <1-69 nM) and inhibits FGFR-dependent signaling in a concentration-dependent manner in FGFR2TEL/V564M-dependent Ba/F3 cells. FIIN-3 also inhibits growth in a panel of cancer cell lines (EC50s = 1.4-499 nM).Suppliers and manufacturers
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific
Shanghai Boyle Chemical Co., Ltd.
Haoyuan Chemexpress Co., Ltd.
MedChemexpress LLC
HangZhou YuHao Chemical Technology Co., Ltd.
Shanghai Lollane Biological Technology Co.,Ltd.