FRAX1036
|
- $46 - $2200
- Product name: FRAX1036
- CAS: 1432908-05-8
- MF: C28H32ClN7O
- MW: 518.05
- EINECS:
- MDL Number:MFCD30187513
- Synonyms:FRAX1036;FRAX1036 (Free base);FRAX-1036;FRAX 1036;CS-2271;Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-[2-chloro-4-(6-methyl-2-pyrazinyl)phenyl]-8-ethyl-2-[[2-(1-methyl-4-piperidinyl)ethyl]amino]-;6-(2-Chloro-4-(6-methylpyrazin-2-yl)phenyl)-8-ethyl-2-((2-(1-methylpiperidin-4-yl)ethyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one;FRAX 1036,Inhibitor,p21 activated kinases,PAK,FRAX1036,inhibit,FRAX-1036
24 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number9316DU
- Product description6-[2-Chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-[2-(1-methylpiperidin-4-yl)ethylamino]pyrido[2,3-d]pyrimidin-7-one
- Packaging25mg
- Price$974
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA374154
- Product descriptionFRAX1036 98+%
- Packaging1mg
- Price$46
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA374154
- Product descriptionFRAX1036 98+%
- Packaging5mg
- Price$92
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA374154
- Product descriptionFRAX1036 98+%
- Packaging10mg
- Price$126
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA374154
- Product descriptionFRAX1036 98+%
- Packaging25mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA374154
- Product descriptionFRAX1036 98+%
- Packaging50mg
- Price$221
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA374154
- Product descriptionFRAX1036 98+%
- Packaging100mg
- Price$287
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA374154
- Product descriptionFRAX1036 98+%
- Packaging250mg
- Price$574
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA374154
- Product descriptionFRAX1036 98+%
- Packaging1g
- Price$1433
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002516
- Product descriptionFRAX1036 95.00%
- Packaging5MG
- Price$501.28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6180
- Product descriptionFRAX1036
- Packaging50mg
- Price$1386
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number20711
- Product descriptionFRAX1036 ≥98%
- Packaging1mg
- Price$47
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20711
- Product descriptionFRAX1036 ≥98%
- Packaging5mg
- Price$206
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20711
- Product descriptionFRAX1036 ≥98%
- Packaging10mg
- Price$360
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20711
- Product descriptionFRAX1036 ≥98%
- Packaging25mg
- Price$788
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5585
- Product descriptionFRAX1036 99.32%
- Packaging1mg
- Price$60
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 9316DU | 6-[2-Chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-[2-(1-methylpiperidin-4-yl)ethylamino]pyrido[2,3-d]pyrimidin-7-one | 25mg | $974 | 2021-12-16 | Buy |
| Ambeed | A374154 | FRAX1036 98+% | 1mg | $46 | 2021-12-16 | Buy |
| Ambeed | A374154 | FRAX1036 98+% | 5mg | $92 | 2021-12-16 | Buy |
| Ambeed | A374154 | FRAX1036 98+% | 10mg | $126 | 2021-12-16 | Buy |
| Ambeed | A374154 | FRAX1036 98+% | 25mg | $170 | 2021-12-16 | Buy |
| Ambeed | A374154 | FRAX1036 98+% | 50mg | $221 | 2021-12-16 | Buy |
| Ambeed | A374154 | FRAX1036 98+% | 100mg | $287 | 2021-12-16 | Buy |
| Ambeed | A374154 | FRAX1036 98+% | 250mg | $574 | 2021-12-16 | Buy |
| Ambeed | A374154 | FRAX1036 98+% | 1g | $1433 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002516 | FRAX1036 95.00% | 5MG | $501.28 | 2021-12-16 | Buy |
| ApexBio Technology | B6180 | FRAX1036 | 50mg | $1386 | 2021-12-16 | Buy |
| Cayman Chemical | 20711 | FRAX1036 ≥98% | 1mg | $47 | 2024-03-01 | Buy |
| Cayman Chemical | 20711 | FRAX1036 ≥98% | 5mg | $206 | 2024-03-01 | Buy |
| Cayman Chemical | 20711 | FRAX1036 ≥98% | 10mg | $360 | 2024-03-01 | Buy |
| Cayman Chemical | 20711 | FRAX1036 ≥98% | 25mg | $788 | 2024-03-01 | Buy |
| ChemScene | CS-5585 | FRAX1036 99.32% | 1mg | $60 | 2021-12-16 | Buy |
Properties
Boiling point :669.8±65.0 °C(Predicted)
Density :1?+-.0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :9.46±0.10(Predicted)
color :White to light yellow
Density :1?+-.0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :9.46±0.10(Predicted)
color :White to light yellow
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
FRAX1036 is a selective inhibitor of p21-activated kinase 1 (PAK1), a serine/threonine kinase downstream of Rac1 and Cdc42 that is involved in tumorigenesis. It can induce apoptosis in breast cancer cells and has been shown to potentiate the activity of the microtubule stabilizing agent, docetaxel . Disruption of PAK1 via FRAX1036 has been used to inhibit oncogenic KRAS signaling in non-small cell lung cancer cells.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Hangzhou MolCore BioPharmatech Co.,Ltd.
TargetMol Chemicals Inc.
Aladdin Scientific
Amadis Chemical Company Limited
Shanghai Chaolan Chemical Technology Center
Haoyuan Chemexpress Co., Ltd.
MedChemexpress LLC
Shanghai Lollane Biological Technology Co.,Ltd.
Shanghai EFE Biological Technology Co., Ltd.