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ChemicalBook >> CAS DataBase List >> FTI-276

FTI-276

FTI-276 price.
  • $245 - $2200
  • Product name: FTI-276
  • CAS: 170006-72-1
  • MF: C21H27N3O3S2
  • MW: 433.59
  • EINECS:
  • MDL Number:MFCD03700738
  • Synonyms:N-[4-[2-(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE TRIFLUOROACETATE SALT;N-[2-PHENYL-4-N[2(R)-AMINO-3-MERCAPTOPROPYLAMINO BENZOYL]-METHIONINE, TFA;FTI-276;FTI-276 trifluoroacetate salt;ZIXDDEATQSBHHL-BEFAXECRSA-N;L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-
8 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ChemScene
  • Sigma-Aldrich
  • Usbiological
Package
  • 250μG
  • 1MG
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0066839
  • Product descriptionFTI-276 TRIFLUOROACETATE SALT 95.00%
  • Packaging5MG
  • Price$1121.22
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0066839
  • Product descriptionFTI-276 TRIFLUOROACETATE SALT 95.00%
  • Packaging1MG
  • Price$676.71
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0009428
  • Product descriptionFTI276
  • Packaging5mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0009428
  • Product descriptionFTI276
  • Packaging10mg
  • Price$680
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0009428
  • Product descriptionFTI276
  • Packaging25mg
  • Price$1350
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0009428
  • Product descriptionFTI276
  • Packaging50mg
  • Price$2200
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number344550
  • Product descriptionFTI-276 A highly potent and selective CAAX peptidomimetic of the carboxyl terminal of Ras proteins that inhibits farnesyl transferase (FTase) in vitro (IC?? = 500 pM).
  • Packaging250μG
  • Price$245
  • Updated2024-03-01
  • Buy
  • ManufacturerUsbiological
  • Product number255340
  • Product descriptionFTI 276
  • Packaging1mg
  • Price$389
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation HCH0066839 FTI-276 TRIFLUOROACETATE SALT 95.00% 5MG $1121.22 2021-12-16 Buy
American Custom Chemicals Corporation HCH0066839 FTI-276 TRIFLUOROACETATE SALT 95.00% 1MG $676.71 2021-12-16 Buy
ChemScene CS-0009428 FTI276 5mg $400 2021-12-16 Buy
ChemScene CS-0009428 FTI276 10mg $680 2021-12-16 Buy
ChemScene CS-0009428 FTI276 25mg $1350 2021-12-16 Buy
ChemScene CS-0009428 FTI276 50mg $2200 2021-12-16 Buy
Sigma-Aldrich 344550 FTI-276 A highly potent and selective CAAX peptidomimetic of the carboxyl terminal of Ras proteins that inhibits farnesyl transferase (FTase) in vitro (IC?? = 500 pM). 250μG $245 2024-03-01 Buy
Usbiological 255340 FTI 276 1mg $389 2021-12-16 Buy

Properties

Boiling point :715.6±60.0 °C(Predicted)
Density :1.272±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :H2O: >5 mg/mL, soluble
form :solid
pka :3.54±0.10(Predicted)
color :off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

FTI-276 trifluoroacetate salt is a highly potent RasCAAX peptidomimetic which antagonizes both H and K-Ras oncogenic signaling. This compound inhibits farnesyltransferase (Ftase) in vitro with an IC50 of 500 pM. RasCAAX as an anti-cancer agent.