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ChemicalBook >> CAS DataBase List >> Firocoxib

Firocoxib

Firocoxib price.
  • $44 - $1400
  • Product name: Firocoxib
  • CAS: 189954-96-9
  • MF: C17H20O5S
  • MW: 336.4
  • EINECS:200-001-2
  • MDL Number:MFCD09837800
  • Synonyms:ML 1785713;Previcox;3-Cyclopropylmethoxy-4-(4-methanesulfonylphenyl)-5,5-dimethyl-5H-furan-2-one;FIROCOXIB;2(5H)-Furanone, 3-(cyclopropylmethoxy)-5,5-dimethyl-4-4-(methylsulfonyl)phenyl-;3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2- one;3-(Cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone;Equioxx
16 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAK Scientific
  • Product number3675AH
  • Product descriptionFirocoxib
  • Packaging10mg
  • Price$194
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4807
  • Product descriptionFirocoxib
  • Packaging10mg
  • Price$303
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS473401
  • Product description3-(Cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one ≥99%
  • Packaging2mg
  • Price$64
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS473401
  • Product description3-(Cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one ≥99%
  • Packaging5mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC23291
  • Product descriptionFirocoxib
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC23291
  • Product descriptionFirocoxib
  • Packaging50mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number28286
  • Product descriptionFirocoxib
  • Packaging10mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28286
  • Product descriptionFirocoxib
  • Packaging50mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28286
  • Product descriptionFirocoxib
  • Packaging100mg
  • Price$363
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM196398
  • Product description3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one 95+%
  • Packaging100mg
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3419
  • Product descriptionFirocoxib 98.42%
  • Packaging5mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3419
  • Product descriptionFirocoxib 98.42%
  • Packaging10mg
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3419
  • Product descriptionFirocoxib 98.42%
  • Packaging50mg
  • Price$688
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002845
  • Product descriptionFirocoxib 98+%
  • Packaging50mg
  • Price$592
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8917
  • Product descriptionFirocoxib >98%
  • Packaging1g
  • Price$1400
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberF356000
  • Product descriptionFirocoxib
  • Packaging1mg
  • Price$70
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3675AH Firocoxib 10mg $194 2021-12-16 Buy
ApexBio Technology B4807 Firocoxib 10mg $303 2021-12-16 Buy
Arctom AS473401 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one ≥99% 2mg $64 2021-12-16 Buy
Arctom AS473401 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one ≥99% 5mg $105 2021-12-16 Buy
Biosynth Carbosynth FC23291 Firocoxib 10mg $50 2021-12-16 Buy
Biosynth Carbosynth FC23291 Firocoxib 50mg $150 2021-12-16 Buy
Cayman Chemical 28286 Firocoxib 10mg $44 2024-03-01 Buy
Cayman Chemical 28286 Firocoxib 50mg $193 2024-03-01 Buy
Cayman Chemical 28286 Firocoxib 100mg $363 2024-03-01 Buy
Chemenu CM196398 3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one 95+% 100mg $252 2021-12-16 Buy
ChemScene CS-3419 Firocoxib 98.42% 5mg $144 2021-12-16 Buy
ChemScene CS-3419 Firocoxib 98.42% 10mg $192 2021-12-16 Buy
ChemScene CS-3419 Firocoxib 98.42% 50mg $688 2021-12-16 Buy
Crysdot CD31002845 Firocoxib 98+% 50mg $592 2021-12-16 Buy
DC Chemicals DC8917 Firocoxib >98% 1g $1400 2021-12-16 Buy
TRC F356000 Firocoxib 1mg $70 2021-12-16 Buy

Properties

Melting point :78-80°C
Boiling point :563.9±50.0 °C(Predicted)
Density :1.31
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
InChI :InChI=1S/C17H20O5S/c1-17(2)14(12-6-8-13(9-7-12)23(3,19)20)15(16(18)22-17)21-10-11-4-5-11/h6-9,11H,4-5,10H2,1-3H3
InChIKey :FULAPETWGIGNMT-UHFFFAOYSA-N
SMILES :O1C(C)(C)C(C2=CC=C(S(C)(=O)=O)C=C2)=C(OCC2CC2)C1=O

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P281 Use personal protective equipment as required.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P314 Get medical advice/attention if you feel unwell.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Firocoxib is a selective inhibitor of COX-2 (IC50s = 0.13 and 7.5 μM for COX-2 and COX-1, respectively, in isolated cat blood). It inhibits LPS-induced production of prostaglandin E2 (PGE2; ) in isolated dog, horse, and cat whole blood ex vivo. Firocoxib decreases lameness, induces analgesia, and improves range of motion in dogs and horses with osteoarthritis when administered at doses of 5 and 0.1 mg/kg per day, respectively. Formulations containing firocoxib have been used in dogs and horses with osteoarthritis.

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