Flavopiridol
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- $51 - $2607.41
- Product name: Flavopiridol
- CAS: 146426-40-6
- MF: C21H20ClNO5
- MW: 401.84
- EINECS:
- MDL Number:MFCD20501884
- Synonyms:FLAVOPIRIDOL;2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3s,4r)-3-hydroxy-1-methyl-4-piperidyl]chromen-4-one;4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-;(-)cis-5,7-Dihydroxy-2-(2-chlorophenyl)-8-(4-(3-hydroxy-1-methyl)piperidinyl)-4H-1-benzopyran-4-one;C077990;Hmr 1275;L 868275;L-868275
28 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500MG
- 1g
- ManufacturerAK Scientific
- Product numberV0695
- Product descriptionFlavopiridol
- Packaging100mg
- Price$896
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000100
- Product descriptionFLAVOPIRIDOL 95.00%
- Packaging500MG
- Price$2607.41
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3417
- Product descriptionFlavopiridol
- Packaging100mg
- Price$366
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3417
- Product descriptionFlavopiridol
- Packaging1g
- Price$2299
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154639
- Product descriptionFlavopiridol >99%
- Packaging100mg
- Price$690.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154639
- Product descriptionFlavopiridol >99%
- Packaging250mg
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154639
- Product descriptionFlavopiridol >99%
- Packaging1g
- Price$2245.7
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFF65024
- Product descriptionFlavopiridol
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFF65024
- Product descriptionFlavopiridol
- Packaging50mg
- Price$262.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number26024
- Product descriptionFlavopiridol ≥95%
- Packaging5mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number26024
- Product descriptionFlavopiridol ≥95%
- Packaging25mg
- Price$208
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number26024
- Product descriptionFlavopiridol ≥95%
- Packaging50mg
- Price$384
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number26024
- Product descriptionFlavopiridol ≥95%
- Packaging100mg
- Price$656
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0018
- Product descriptionFlavopiridol 99.72%
- Packaging5mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0018
- Product descriptionFlavopiridol 99.72%
- Packaging10mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0018
- Product descriptionFlavopiridol 99.72%
- Packaging50mg
- Price$234
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | V0695 | Flavopiridol | 100mg | $896 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000100 | FLAVOPIRIDOL 95.00% | 500MG | $2607.41 | 2021-12-16 | Buy |
ApexBio Technology | A3417 | Flavopiridol | 100mg | $366 | 2021-12-16 | Buy |
ApexBio Technology | A3417 | Flavopiridol | 1g | $2299 | 2021-12-16 | Buy |
Biorbyt Ltd | orb154639 | Flavopiridol >99% | 100mg | $690.2 | 2021-12-16 | Buy |
Biorbyt Ltd | orb154639 | Flavopiridol >99% | 250mg | $1208.7 | 2021-12-16 | Buy |
Biorbyt Ltd | orb154639 | Flavopiridol >99% | 1g | $2245.7 | 2021-12-16 | Buy |
Biosynth Carbosynth | FF65024 | Flavopiridol | 10mg | $75 | 2021-12-16 | Buy |
Biosynth Carbosynth | FF65024 | Flavopiridol | 50mg | $262.5 | 2021-12-16 | Buy |
Cayman Chemical | 26024 | Flavopiridol ≥95% | 5mg | $57 | 2024-03-01 | Buy |
Cayman Chemical | 26024 | Flavopiridol ≥95% | 25mg | $208 | 2024-03-01 | Buy |
Cayman Chemical | 26024 | Flavopiridol ≥95% | 50mg | $384 | 2024-03-01 | Buy |
Cayman Chemical | 26024 | Flavopiridol ≥95% | 100mg | $656 | 2024-03-01 | Buy |
ChemScene | CS-0018 | Flavopiridol 99.72% | 5mg | $60 | 2021-12-16 | Buy |
ChemScene | CS-0018 | Flavopiridol 99.72% | 10mg | $84 | 2021-12-16 | Buy |
ChemScene | CS-0018 | Flavopiridol 99.72% | 50mg | $234 | 2021-12-16 | Buy |
Properties
Melting point :52.5 °C
Boiling point :603.6±55.0 °C(Predicted)
Density :1.448±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :insoluble in H2O; ≥40.2 mg/mL in DMSO; ≥85.4 mg/mL in EtOH with gentle warming and ultrasonic
form :Yellow powder.
pka :6.16±0.40(Predicted)
color :Light yellow to yellow
InChIKey :BIIVYFLTOXDAOV-YVEFUNNKSA-N
SMILES :C1(C2=CC=CC=C2Cl)OC2=C([C@H]3CCN(C)C[C@H]3O)C(O)=CC(O)=C2C(=O)C=1
CAS DataBase Reference :146426-40-6(CAS DataBase Reference)
Boiling point :603.6±55.0 °C(Predicted)
Density :1.448±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :insoluble in H2O; ≥40.2 mg/mL in DMSO; ≥85.4 mg/mL in EtOH with gentle warming and ultrasonic
form :Yellow powder.
pka :6.16±0.40(Predicted)
color :Light yellow to yellow
InChIKey :BIIVYFLTOXDAOV-YVEFUNNKSA-N
SMILES :C1(C2=CC=CC=C2Cl)OC2=C([C@H]3CCN(C)C[C@H]3O)C(O)=CC(O)=C2C(=O)C=1
CAS DataBase Reference :146426-40-6(CAS DataBase Reference)
Safety Information
Symbol(GHS): |
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Signal word: | Warning | ||||||||||||||||||||||||||||
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Precautionary statements: |
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Description
Flavopiridol is a synthetic flavone compound that inhibits the phosphorylation of cyclin-dependent kinases (Cdks) and suppresses expression of cyclin D1 and D3, interrupting the central role of Cdks in the regulation of the cell cycle and consequently promoting apoptosis. This action has been exploited in studies investigating the suppression of oncogenic proliferation, synovial hyperplasia, and joint destruction related to rheumatoid arthritis. Flavopiridol is an inhibitor of Cdk1, Cdk10, Cdk11, Cdk2, Cdk3, Cdk4, Cdk5, Cdk6, Cdk7, Cdk8 and Cdk9.Related product price
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