G-36
|
- $32 - $2200
- Product name: G-36
- CAS: 1392487-51-2
- MF: C22H22BrNO2
- MW: 412.32
- EINECS:
- MDL Number:MFCD28137712
- Synonyms:G-36;(3aS,4R,9bR)-4-(6-Bromo-1,3-benzodioxol-5-yl)-8-isopropyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline;(3aS,4R,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl)-8-isopropyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline;(±)-(3aR*,4S*,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-8-(1-methylethyl)-3H-cyclopenta[c]quinoline;G-36;G36;G 36;G36;G 36;3H-Cyclopenta[c]quinoline, 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-8-(1-methylethyl)-, (3aR,4S,9bS)-rel-;rel-(3aR,4S,9bS)-4-(6-Bromobenzo[d][1,3]dioxol-5-yl)-8-isopropyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
11 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- DC Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10mg
- 50mg
- 1g
- ManufacturerAK Scientific
- Product number7588DW
- Product description(3As,4R,9bR)-4-(6-bromo-1,3-benzodioxol-5-yl)-8-propan-2-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
- Packaging50mg
- Price$1028
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5707
- Product descriptionG-36
- Packaging10mg
- Price$192
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14397
- Product descriptionG-36 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14397
- Product descriptionG-36 ≥98%
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14397
- Product descriptionG-36 ≥98%
- Packaging10mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14397
- Product descriptionG-36 ≥98%
- Packaging50mg
- Price$836
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC10816
- Product descriptionG-36 >98%
- Packaging1g
- Price$2200
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number4759
- Product descriptionG-36 ≥99%(HPLC)
- Packaging10
- Price$212
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberG932038
- Product descriptionG-36
- Packaging1mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberG932038
- Product descriptionG-36
- Packaging5mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number451023
- Product descriptionG-36
- Packaging1mg
- Price$389
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 7588DW | (3As,4R,9bR)-4-(6-bromo-1,3-benzodioxol-5-yl)-8-propan-2-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline | 50mg | $1028 | 2021-12-16 | Buy |
| ApexBio Technology | B5707 | G-36 | 10mg | $192 | 2021-12-16 | Buy |
| Cayman Chemical | 14397 | G-36 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 14397 | G-36 ≥98% | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 14397 | G-36 ≥98% | 10mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 14397 | G-36 ≥98% | 50mg | $836 | 2024-03-01 | Buy |
| DC Chemicals | DC10816 | G-36 >98% | 1g | $2200 | 2021-12-16 | Buy |
| Tocris | 4759 | G-36 ≥99%(HPLC) | 10 | $212 | 2021-12-16 | Buy |
| TRC | G932038 | G-36 | 1mg | $100 | 2021-12-16 | Buy |
| TRC | G932038 | G-36 | 5mg | $400 | 2021-12-16 | Buy |
| Usbiological | 451023 | G-36 | 1mg | $389 | 2021-12-16 | Buy |
Properties
Melting point :138-141°C
Boiling point :478.4±45.0 °C(Predicted)
Density :1.367±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :4.51±0.40(Predicted)
color :Off-White to Pale Yellow
Boiling point :478.4±45.0 °C(Predicted)
Density :1.367±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :4.51±0.40(Predicted)
color :Off-White to Pale Yellow
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
G protein-coupled estrogen receptor (GPER), or GPR30, specifically binds natural and man-made estrogens. It is thought to be involved in estrogen-sensitive cancers. GPER knockout mice are fertile, although they exhibit thymic atrophy, impaired glucose tolerance, and altered bone growth. G-36 is a cell-permeable non-steroidal antagonist of GPER, inhibiting activation by either 17β-estradiol or the GPER-selective agonist G-1 (IC50 = 112 and 165 nM, respectively). It has no detectable binding activity to either ERα or ERβ. G-36 blocks the activation of PI3K or calcium mobilization triggered by estrogen through GPER and it suppresses ERK activation by estrogen or G-1 but not by EGF. G-36 can be used in combination with GPER-selective agonists, like G-1, to distinguish the roles of GPER from those of ERα and ERβ in complex biological systems.Suppliers and manufacturers
TargetMol Chemicals Inc.
Aladdin Scientific
BOC Sciences
ChemStrong Scientific Co.,Ltd
ShangHai AmK Pharmaceutical Technology Co., Ltd.
EMMX Biotechnology LLC
Tianjin Kailiqi Biotechnology Co., Ltd.
Shenzhen Polymeri Biochemical Technology Co., Ltd.
DC Chemicals
Changzhou Chenhong Biotechnology Co., Ltd.