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ChemicalBook >> CAS DataBase List >> GLS1 Inhibitor

GLS1 Inhibitor

GLS1 Inhibitor price.
  • $32 - $201
  • Product name: GLS1 Inhibitor
  • CAS: 1832646-52-2
  • MF: C19H21N7O2S
  • MW: 411.48
  • EINECS:
  • MDL Number:
  • Synonyms:4-thiadiazol-2-yl]-benzeneacetamide;αS-methoxy-N-[5-[[(3R)-1-(3-pyridazinyl)-3-pyrrolidinyl]amino]-1;ΑS-METHOXY-N-[5-[[(3R)-1-(3-PYRIDAZINYL)-3-PYRROLIDINYL]AMINO]-1;3;4-THIADIAZOL-2-YL]-BENZENEACETAMIDE;Benzeneacetamide, α-methoxy-N-[5-[[(3R)-1-(3-pyridazinyl)-3-pyrrolidinyl]amino]-1,3,4-thiadiazol-2-yl]-, (αS)-;GLS1 Inhibitor,GLS-1 Inhibitor
4 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number4134ED
  • Product descriptionCID100951644
  • Packaging5mg
  • Price$201
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number28581
  • Product descriptionGLS1 Inhibitor
  • Packaging10mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28581
  • Product descriptionGLS1 Inhibitor
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28581
  • Product descriptionGLS1 Inhibitor
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4134ED CID100951644 5mg $201 2021-12-16 Buy
Cayman Chemical 28581 GLS1 Inhibitor 10mg $139 2024-03-01 Buy
Cayman Chemical 28581 GLS1 Inhibitor 5mg $93 2024-03-01 Buy
Cayman Chemical 28581 GLS1 Inhibitor 1mg $32 2024-03-01 Buy

Properties

Density :1.425±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
form :A crystalline solid
pka :7.42±0.50(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

GLS1 inhibitor is an inhibitor of glutaminase 1 (GLS1; IC50 = 0.021 μM). It inhibits the growth of NCI H1703 non-small cell lung cancer (NSCLC) cells in vitro (GI50 = 0.011 μM). GLS1 inhibitor (100 mg/kg) reduces tumor growth, increases tumor levels of glutamine, and decreases tumor levels of glutamate and aspartate in an NCI H1703 mouse xenograft model.