GSK269962A
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- $37 - $4023.9
- Product name: GSK269962A
- CAS: 850664-21-0
- MF: C29H30N8O5
- MW: 570.6
- EINECS:
- MDL Number:MFCD09970310
- Synonyms:GSK 269962;N-[3-[[2-(4-Aminofurazan-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy]phenyl]-4-[[2-(4-morpholinyl)ethyl]oxy]benzamide;GSK269962A(GSK269962);N-(3-((2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl)oxy)phenyl)-4-(2-morpholinoethoxy)benzamide;GSK269962A ISO 9001：2015 REACH;GSK269962 (GSK269962A);ROCK inhibitor GSK269962A;GSK-269962 95%
27 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
Package
- 25mg
- 10
- 2MG
- 50
- 1mg
- 5mg
- 10mg
- 50mg
- 100mg
- 250mg
- 1000mg
- 1g
- ManufacturerAK Scientific
- Product number3703AH
- Product descriptionGSK269962A
- Packaging1mg
- Price$111
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3703AH
- Product descriptionGSK269962A
- Packaging5mg
- Price$158
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3703AH
- Product descriptionGSK269962A
- Packaging10mg
- Price$192
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3703AH
- Product descriptionGSK269962A
- Packaging250mg
- Price$1887
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000296
- Product descriptionGSK-269962A 95.00%
- Packaging2MG
- Price$516
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000296
- Product descriptionGSK-269962A 95.00%
- Packaging5MG
- Price$833.78
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3392
- Product descriptionGSK269962A
- Packaging50mg
- Price$879
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1167
- Product descriptionGSK269962A-GSK269962 99%
- Packaging5mg
- Price$115.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181100
- Product descriptionGSK269962A(GSK269962) >98%
- Packaging100mg
- Price$1133.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181100
- Product descriptionGSK269962A(GSK269962) >98%
- Packaging250mg
- Price$2172.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181100
- Product descriptionGSK269962A(GSK269962) >98%
- Packaging1000mg
- Price$4023.9
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBG164808
- Product descriptionGSK 269962
- Packaging10mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBG164808
- Product descriptionGSK 269962
- Packaging50mg
- Price$612.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19180
- Product descriptionGSK269962 ≥95%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19180
- Product descriptionGSK269962 ≥95%
- Packaging5mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19180
- Product descriptionGSK269962 ≥95%
- Packaging10mg
- Price$283
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3703AH | GSK269962A | 1mg | $111 | 2021-12-16 | Buy |
| AK Scientific | 3703AH | GSK269962A | 5mg | $158 | 2021-12-16 | Buy |
| AK Scientific | 3703AH | GSK269962A | 10mg | $192 | 2021-12-16 | Buy |
| AK Scientific | 3703AH | GSK269962A | 250mg | $1887 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000296 | GSK-269962A 95.00% | 2MG | $516 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000296 | GSK-269962A 95.00% | 5MG | $833.78 | 2021-12-16 | Buy |
| ApexBio Technology | B3392 | GSK269962A | 50mg | $879 | 2021-12-16 | Buy |
| Axon Medchem | Axon1167 | GSK269962A-GSK269962 99% | 5mg | $115.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181100 | GSK269962A(GSK269962) >98% | 100mg | $1133.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181100 | GSK269962A(GSK269962) >98% | 250mg | $2172.6 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181100 | GSK269962A(GSK269962) >98% | 1000mg | $4023.9 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BG164808 | GSK 269962 | 10mg | $175 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BG164808 | GSK 269962 | 50mg | $612.5 | 2021-12-16 | Buy |
| Cayman Chemical | 19180 | GSK269962 ≥95% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 19180 | GSK269962 ≥95% | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 19180 | GSK269962 ≥95% | 10mg | $283 | 2024-03-01 | Buy |
Properties
Melting point :125 - 127°C
Density :1.45
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :13.19±0.70(Predicted)
color :Off-White
Density :1.45
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :13.19±0.70(Predicted)
color :Off-White
Safety Information
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Description
Two Rho-associated kinases (ROCKS), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal. GSK269962 is a selective ROCK inhibitor with IC50 values of 1.6 and 6 nM for ROCK-I and ROCK-II, respectively. It displays greater than 30-fold selectivity for ROCK against a panel of serine/threonine kinases. GSK269962 has been shown to block the generation of inflammatory cytokines in lipopolysaccharide-stimulated monocytes and to induce vasorelaxation in preconstricted rat aorta (IC50 = 35 nM). Oral administration of 1-30 mg/kg GSK269962 can dose-dependently lower blood pressure in spontaneously hypertensive rats.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
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Hebei Fengjia New Material Co., Ltd
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd
![N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c] pyridin-6-yl]oxy}phenyl)-4-[2-(4-morpholinyl)ethoxy]benzamide](https://img.chemicalbook.com/ProductImageEN/2020-1/small/35a3e43e-66d0-4062-a2d4-04b7bdec5403.png){kind=small}
