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ChemicalBook >> CAS DataBase List >> GW311616A

GW311616A

GW311616A price.
  • $81 - $2295
  • Product name: GW311616A
  • CAS: 197890-44-1
  • MF: C19H32ClN3O4S
  • MW: 433.99
  • EINECS:
  • MDL Number:MFCD06411566
  • Synonyms:CS-1260;GW 311616A;GW-311616A;GW 311616A - GW 311616 hydrochloride;GW311616 hydrochloride,GW-311616 hydrochloride
Price17 Properties Safety Information Description
17 prices
Selected condition：
Brand
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 10mM(in 1mL DMSO)
  • ManufacturerApexBio Technology
  • Product numberB4676
  • Product descriptionGW311616hydrochloride
  • Packaging100mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4676
  • Product descriptionGW311616hydrochloride
  • Packaging5mg
  • Price$345
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4676
  • Product descriptionGW311616hydrochloride
  • Packaging10mM(in 1mL DMSO)
  • Price$460
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4676
  • Product descriptionGW311616hydrochloride
  • Packaging10mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4676
  • Product descriptionGW311616hydrochloride
  • Packaging50mg
  • Price$1550
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2364
  • Product descriptionGW311616A-GW311616hydrochloride 99%
  • Packaging5mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2364
  • Product descriptionGW311616A-GW311616hydrochloride 99%
  • Packaging25mg
  • Price$770
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27957
  • Product descriptionGW 311616A
  • Packaging1mg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27957
  • Product descriptionGW 311616A
  • Packaging5mg
  • Price$238
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27957
  • Product descriptionGW 311616A
  • Packaging10mg
  • Price$396
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3127
  • Product descriptionGW311616(hydrochloride) 98.84%
  • Packaging5mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002783
  • Product descriptionGW311616hydrochloride 98+%
  • Packaging5mg
  • Price$410
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002783
  • Product descriptionGW311616hydrochloride 98+%
  • Packaging10mg
  • Price$590
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002783
  • Product descriptionGW311616hydrochloride 98+%
  • Packaging50mg
  • Price$1650
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002783
  • Product descriptionGW311616hydrochloride 98+%
  • Packaging100mg
  • Price$2295
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN18079
  • Product descriptionGW311616HCl
  • Packaging1mg
  • Price$106
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B4676 GW311616hydrochloride 100mg $210 2021-12-16 Buy
ApexBio Technology B4676 GW311616hydrochloride 5mg $345 2021-12-16 Buy
ApexBio Technology B4676 GW311616hydrochloride 10mM(in 1mL DMSO) $460 2021-12-16 Buy
ApexBio Technology B4676 GW311616hydrochloride 10mg $500 2021-12-16 Buy
ApexBio Technology B4676 GW311616hydrochloride 50mg $1550 2021-12-16 Buy
Axon Medchem Axon2364 GW311616A-GW311616hydrochloride 99% 5mg $198 2021-12-16 Buy
Axon Medchem Axon2364 GW311616A-GW311616hydrochloride 99% 25mg $770 2021-12-16 Buy
Cayman Chemical 27957 GW 311616A 1mg $81 2024-03-01 Buy
Cayman Chemical 27957 GW 311616A 5mg $238 2024-03-01 Buy
Cayman Chemical 27957 GW 311616A 10mg $396 2024-03-01 Buy
ChemScene CS-3127 GW311616(hydrochloride) 98.84% 5mg $550 2021-12-16 Buy
Crysdot CD31002783 GW311616hydrochloride 98+% 5mg $410 2021-12-16 Buy
Crysdot CD31002783 GW311616hydrochloride 98+% 10mg $590 2021-12-16 Buy
Crysdot CD31002783 GW311616hydrochloride 98+% 50mg $1650 2021-12-16 Buy
Crysdot CD31002783 GW311616hydrochloride 98+% 100mg $2295 2021-12-16 Buy
CSNpharm CSN18079 GW311616HCl 1mg $106 2021-12-16 Buy
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Properties

storage temp. :2-8°C
solubility :H2O: 24 mg/mL, soluble
form :solid
color :White to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

GW 311616A is an inhibitor of neutrophil elastase (IC50 = 100 nM). It is selective for neutrophil elastase (IC50 = 22 nM for the human enzyme) over trypsin, cathepsin G, and plasmin (IC50s = >100 μM for all), as well as chymotrypsin and tissue plasminogen activator (IC50s = >3 μM for both), in cell-free assays. GW 311616A (20 μM) inhibits the formation of neutrophil extracellular traps (NETs) induced by phorbol 12-myristate 13-acetate (PMA; ) in isolated human neutrophils. It inhibits intraneutrophil elastase activity in isolated dog blood six hours after administration of a 0.22 mg/kg dose. GW 311616A also inhibits neutrophil elastase in the liver in a mouse model of liver ischemia-reperfusion injury when administered at a dose of 2 mg/kg.

Suppliers and manufacturers

TargetMol Chemicals Inc.
Hangzhou MolCore BioPharmatech Co.,Ltd.
Amadis Chemical Company Limited ShangHai KenEn Chemical Technology Co., Ltd. SPIRO PHARMA BOC Sciences Shanghai EFE Biological Technology Co., Ltd. Musechem DC Chemicals Cckinase, Inc.