Goserelin acetate
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- $32 - $3100
- Product name: Goserelin acetate
- CAS: 145781-92-6
- MF: C61H88N18O16
- MW: 1329.49
- EINECS:652-995-1
- MDL Number:MFCD00867894
- Synonyms:PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2;[(T-BU)DSER6, (AZA)GLY10]-LH-RH;[(T-BU)DSER6, (AZA)GLY10]-LUTEINIZING HORMONE-RELEASING HORMONE;GOSERELIN HCL[PYR-HIS-TRP-SER-TYR-D-SER(T-BU)-LEU-ARG-PRO-AZAGLY-NH2];1-9-Luteinizing hormone-releasing factor (swine), 6-(o-(1,1-dimethylethyl)-D-serine)-, 2-(aminocarbonyl)hydrazide, acetate (salt);Fertilan;GLP-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZA-GLY-NH2;(D-SER(TBU)6,AZAGLY10)-LHRH
20 prices
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Brand
- AHH
- AvaChem
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 5mg
- y0000125
- 10mg
- 10
- y0001473
- 25mg
- 50mg
- 0.05g
- 100mg
- 250mg
- 1g
- ManufacturerAHH
- Product numberAPI-1275
- Product descriptionGoserelin acetate 98%
- Packaging0.05g
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2222S
- Product descriptionGoserelin Acetate
- Packaging50mg
- Price$890
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2222S
- Product descriptionGoserelin Acetate
- Packaging1g
- Price$3100
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFG44023
- Product descriptionGoserelin acetate
- Packaging50mg
- Price$375
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number24071
- Product descriptionGoserelin (acetate) ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24071
- Product descriptionGoserelin (acetate) ≥98%
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24071
- Product descriptionGoserelin (acetate) ≥98%
- Packaging10mg
- Price$199
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-4509
- Product descriptionGoserelin acetate 99.96%
- Packaging5mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4509
- Product descriptionGoserelin acetate 99.96%
- Packaging10mg
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4509
- Product descriptionGoserelin acetate 99.96%
- Packaging50mg
- Price$396
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC31118
- Product descriptionICI118630
- Packaging1g
- Price$1600
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC31118
- Product descriptionICI118630
- Packaging250mg
- Price$800
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number18874
- Product descriptionGoserelin acetate >99%
- Packaging5mg
- Price$990
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberG4919
- Product descriptionGoserelin acetate ≥99% (HPLC), white powder
- Packaging5mg
- Price$110.8
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberY0000125
- Product descriptionGoserelin European Pharmacopoeia (EP) Reference Standard
- Packagingy0000125
- Price$220
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberY0001473
- Product descriptionGoserelin for NMR identification European Pharmacopoeia (EP) Reference Standard
- Packagingy0001473
- Price$223
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | API-1275 | Goserelin acetate 98% | 0.05g | $420 | 2021-12-16 | Buy |
| AvaChem | 2222S | Goserelin Acetate | 50mg | $890 | 2021-12-16 | Buy |
| AvaChem | 2222S | Goserelin Acetate | 1g | $3100 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FG44023 | Goserelin acetate | 50mg | $375 | 2021-12-16 | Buy |
| Cayman Chemical | 24071 | Goserelin (acetate) ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 24071 | Goserelin (acetate) ≥98% | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 24071 | Goserelin (acetate) ≥98% | 10mg | $199 | 2024-03-01 | Buy |
| ChemScene | CS-4509 | Goserelin acetate 99.96% | 5mg | $84 | 2021-12-16 | Buy |
| ChemScene | CS-4509 | Goserelin acetate 99.96% | 10mg | $132 | 2021-12-16 | Buy |
| ChemScene | CS-4509 | Goserelin acetate 99.96% | 50mg | $396 | 2021-12-16 | Buy |
| DC Chemicals | DC31118 | ICI118630 | 1g | $1600 | 2021-12-16 | Buy |
| DC Chemicals | DC31118 | ICI118630 | 250mg | $800 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 18874 | Goserelin acetate >99% | 5mg | $990 | 2021-12-16 | Buy |
| Sigma-Aldrich | G4919 | Goserelin acetate ≥99% (HPLC), white powder | 5mg | $110.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | Y0000125 | Goserelin European Pharmacopoeia (EP) Reference Standard | y0000125 | $220 | 2024-03-01 | Buy |
| Sigma-Aldrich | Y0001473 | Goserelin for NMR identification European Pharmacopoeia (EP) Reference Standard | y0001473 | $223 | 2024-03-01 | Buy |
Properties
Melting point :>190°C (dec.)
storage temp. :-20°C
solubility :H2O: 20 mg/mL, clear, colorless
form :white powder
color :White to Off-White
Stability :Hygroscopic
InChIKey :IKDXDQDKCZPQSZ-JHYYTBFNSA-N
storage temp. :-20°C
solubility :H2O: 20 mg/mL, clear, colorless
form :white powder
color :White to Off-White
Stability :Hygroscopic
InChIKey :IKDXDQDKCZPQSZ-JHYYTBFNSA-N
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Goserelin acetate, like leuprolide acetate, is a synthetic superagonist nonapeptide analogue of GnRH that possesses greater potency than the natural hormone. Note that it contains D-Ser(But) and NH-NHCONH2 in place of Gly6 and Gly10-NH2, respectively. That is, the C terminal modification simply has an NH substituting for the CH2 of Gly, and like the C-terminal change in leuprolide acetate, this inhibits enzymatic degradation of the peptide by the postproline carboxyamide peptidase.Goserelin acetate is available in the form of a small, solid pellet that is administered as an SC implant for the palliative treatment of advanced, metastatic breast cancer in pre- and perimenopausal women or, similarly, as a palliative in advanced prostatic cancer. The rationale for this drug's use is, as described above, its ability as a superagonist to bring the levels of estradiol or testosterone to near castrate levels, thus slowing the progression of breast or prostate carcinoma, respectively. Additionally, goserelin acetate is approved for use in treating endometriosis for up to 6 months.
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Suppliers and manufacturers
Henan Tianfu Chemical Co.,Ltd.
Shenzhen Nexconn Pharmatechs Ltd
Hubei xin bonus chemical co. LTD
BOC Sciences
Beijing Yibai Biotechnology Co., Ltd
Chongqing Chemdad Co., Ltd
