HOE-140
|
- $81 - $5654.2
- Product name: HOE-140
- CAS: 138614-30-9
- MF: C59H89N19O13S.C2H4O2
- MW: 1364.59
- EINECS:206-141-6
- MDL Number:MFCD04112967
- Synonyms:Firazyr;HOE 140 SYNTHETIC >99% SELECTIVE B2 BRAD YKIN;d-arg-l-arg-l-pro-l-hyp-gly-l-(2-thienyl)ala-l-ser-d-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-l-(2α,3β,7aβ)-octahydro-1h-indole-2-carbonyl-l-arg;Icatibant acetate, D-Arg-L-Arg-L-Pro-L-Hyp-Gly-L-(2-thienyl)Ala-L-Ser-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3β,7aβ)-octahydro-1H-indole-2-carbonyl-L-Arg;HOE 140 Acetate;lcatibant Acetate;HOE-140 (Icatibant);HOE140; ICATIBANT;HOE 140
16 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 250μg
- 500μg
- 1MG
- 5MG
- 25mg
- 100mg
- 250mg
- 1g
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010072
- Product descriptionICATIBANT ACETATE 95.00%
- Packaging1MG
- Price$525
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010072
- Product descriptionICATIBANT ACETATE 95.00%
- Packaging5MG
- Price$775
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180804
- Product descriptionHOE-140 (Icatibant) >98%
- Packaging100mg
- Price$2245.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180804
- Product descriptionHOE-140 (Icatibant) >98%
- Packaging250mg
- Price$3282.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180804
- Product descriptionHOE-140 (Icatibant) >98%
- Packaging1g
- Price$5654.2
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number24083
- Product descriptionIcatibant (acetate) ≥98%
- Packaging500μg
- Price$81
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24083
- Product descriptionIcatibant (acetate) ≥98%
- Packaging1mg
- Price$143
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24083
- Product descriptionIcatibant (acetate) ≥98%
- Packaging5mg
- Price$435
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0031296
- Product descriptionIcatibantacetate 99.64%
- Packaging1mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0031296
- Product descriptionIcatibantacetate 99.64%
- Packaging5mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC6314
- Product descriptionIcatibantacetate 98%
- Packaging100mg
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC6314
- Product descriptionIcatibantacetate 98%
- Packaging250mg
- Price$1300
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC6314
- Product descriptionIcatibantacetate 98%
- Packaging1g
- Price$2600
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number46820
- Product descriptionIcatibantAcetate
- Packaging25mg
- Price$1250
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberH157
- Product descriptionHOE 140 ≥94%
- Packaging250μg
- Price$325
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberI163750
- Product descriptionIcatibantAcetate
- Packaging1mg
- Price$140
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0010072 | ICATIBANT ACETATE 95.00% | 1MG | $525 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010072 | ICATIBANT ACETATE 95.00% | 5MG | $775 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180804 | HOE-140 (Icatibant) >98% | 100mg | $2245.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180804 | HOE-140 (Icatibant) >98% | 250mg | $3282.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180804 | HOE-140 (Icatibant) >98% | 1g | $5654.2 | 2021-12-16 | Buy |
| Cayman Chemical | 24083 | Icatibant (acetate) ≥98% | 500μg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 24083 | Icatibant (acetate) ≥98% | 1mg | $143 | 2024-03-01 | Buy |
| Cayman Chemical | 24083 | Icatibant (acetate) ≥98% | 5mg | $435 | 2024-03-01 | Buy |
| ChemScene | CS-0031296 | Icatibantacetate 99.64% | 1mg | $115 | 2021-12-16 | Buy |
| ChemScene | CS-0031296 | Icatibantacetate 99.64% | 5mg | $350 | 2021-12-16 | Buy |
| DC Chemicals | DC6314 | Icatibantacetate 98% | 100mg | $700 | 2021-12-16 | Buy |
| DC Chemicals | DC6314 | Icatibantacetate 98% | 250mg | $1300 | 2021-12-16 | Buy |
| DC Chemicals | DC6314 | Icatibantacetate 98% | 1g | $2600 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 46820 | IcatibantAcetate | 25mg | $1250 | 2021-12-16 | Buy |
| Sigma-Aldrich | H157 | HOE 140 ≥94% | 250μg | $325 | 2024-03-01 | Buy |
| TRC | I163750 | IcatibantAcetate | 1mg | $140 | 2021-12-16 | Buy |
Properties
storage temp. :-20°C
solubility :DMSO:65.0(Max Conc. mg/mL);47.63(Max Conc. mM)
Ethanol:0.25(Max Conc. mg/mL);0.18(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);7.33(Max Conc. mM) form :A crystalline solid
color :White to off-white
solubility :DMSO:65.0(Max Conc. mg/mL);47.63(Max Conc. mM)
Ethanol:0.25(Max Conc. mg/mL);0.18(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);7.33(Max Conc. mM) form :A crystalline solid
color :White to off-white
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Although it is a rare disease, HAE is an autosomal dominant disorder that can be potentially life-threatening when swelling manifests itself within the upper airways. Antagonism of the constitutively expressed B2 receptor, therefore, would not only be beneficial in the treatment of HAE but also find application in inflammatory, allergic, and hyperalgesic disorders.Designed to possess enhanced metabolic stability with the inclusion of five non-proteinogenic amino acids, icatibant is a competitive and selective B2 receptor antagonist (devoid of activity against the inducible B1 receptor) with a Ki of 2.2±0.7 nM, and it is the first downstream targeting agent to receive regulatory approval. It joins purified C1 esterase inhibitor, danazol (an attenuated androgen), and tranexamic acid (an antifibrinolytic agent) as acute and prophylactic treatments for HAE.Related product price
- Calcitonin salmon
$120-4190 - Gonadorelin acetate
$32-300 - Thymosin beta 4 acetate
$185-4105.5
Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Chongqing Chemdad Co., Ltd
Fuxin Pharmaceutical
Hebei Yanxi Chemical Co., Ltd.
