HPOB
|
- $32 - $1240
- Product name: HPOB
- CAS: 1429651-50-2
- MF: C17H18N2O4
- MW: 314.34
- EINECS:
- MDL Number:MFCD27952937
- Synonyms:HPOB;N-hydroxy-4-(2-((2-hydroxyethyl)(phenyl)amino)-2-oxoethyl)benzamide;4-[(hydroxyamino)carbonyl]-N-(2-hydroxyethyl)-N-phenyl- benzeneacetamide HPOB;4-[(Hydroxyamino)carbonyl]-N-(2-hydroxyethyl)-N-phenyl-benzeneacetamide;CS-1829;Benzeneacetamide, 4-[(hydroxyamino)carbonyl]-N-(2-hydroxyethyl)-N-phenyl-;HPOB,HDAC6 inhibitor
16 prices
Selected condition：
Brand
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- ManufacturerApexBio Technology
- Product numberB4890
- Product descriptionHPOB
- Packaging25mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15066
- Product descriptionHPOB ≥95%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15066
- Product descriptionHPOB ≥95%
- Packaging5mg
- Price$100
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15066
- Product descriptionHPOB ≥95%
- Packaging10mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5399
- Product descriptionHPOB
- Packaging5mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5399
- Product descriptionHPOB
- Packaging10mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5399
- Product descriptionHPOB
- Packaging25mg
- Price$192
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5399
- Product descriptionHPOB
- Packaging50mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5399
- Product descriptionHPOB
- Packaging100mg
- Price$468
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD00009632
- Product descriptionHPOB 97%
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD00009632
- Product descriptionHPOB 97%
- Packaging25mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD00009632
- Product descriptionHPOB 97%
- Packaging50mg
- Price$234
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0906
- Product descriptionHPOB ≥98% (HPLC)
- Packaging5mg
- Price$140
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0906
- Product descriptionHPOB ≥98% (HPLC)
- Packaging25mg
- Price$477
- Updated2022-05-15
- Buy
- ManufacturerTRC
- Product numberH671300
- Product descriptionHPOB
- Packaging100mg
- Price$1240
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number451978
- Product descriptionHPOB
- Packaging5mg
- Price$425
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ApexBio Technology | B4890 | HPOB | 25mg | $240 | 2021-12-16 | Buy |
| Cayman Chemical | 15066 | HPOB ≥95% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 15066 | HPOB ≥95% | 5mg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 15066 | HPOB ≥95% | 10mg | $184 | 2024-03-01 | Buy |
| ChemScene | CS-5399 | HPOB | 5mg | $60 | 2021-12-16 | Buy |
| ChemScene | CS-5399 | HPOB | 10mg | $96 | 2021-12-16 | Buy |
| ChemScene | CS-5399 | HPOB | 25mg | $192 | 2021-12-16 | Buy |
| ChemScene | CS-5399 | HPOB | 50mg | $288 | 2021-12-16 | Buy |
| ChemScene | CS-5399 | HPOB | 100mg | $468 | 2021-12-16 | Buy |
| Crysdot | CD00009632 | HPOB 97% | 10mg | $75 | 2021-12-16 | Buy |
| Crysdot | CD00009632 | HPOB 97% | 25mg | $150 | 2021-12-16 | Buy |
| Crysdot | CD00009632 | HPOB 97% | 50mg | $234 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML0906 | HPOB ≥98% (HPLC) | 5mg | $140 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0906 | HPOB ≥98% (HPLC) | 25mg | $477 | 2022-05-15 | Buy |
| TRC | H671300 | HPOB | 100mg | $1240 | 2021-12-16 | Buy |
| Usbiological | 451978 | HPOB | 5mg | $425 | 2021-12-16 | Buy |
Properties
storage temp. :2-8°C
solubility :DMSO: soluble1mg/mL, clear (warmed)
form :powder
color :white to beige
solubility :DMSO: soluble1mg/mL, clear (warmed)
form :powder
color :white to beige
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
HPOB is a potent inhibitor of histone deacetylase 6 (HDAC6; IC50 = 56 nM). It is at least 30-fold less effective against other HDACs. Through its effects on HDAC6, HPOB induces acetylation of α-tubulin but not histones. HPOB reduces the growth, but not the viability, of normal and transformed cells. It enhances the death of transformed cells as triggered by the topoisomerase II inhibitors etoposide and doxorubicin. HPOB enhances the cytotoxicity of the broad spectrum HDAC inhibitor SAHA against cancer cells in nude mice carrying an androgen-dependent CWR22 human prostate cancer xenograft.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Hubei Jusheng Technology Co.,Ltd.
TargetMol Chemicals Inc.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Hefei Hirisun Pharmatech Co., Ltd
InvivoChem
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific
Amadis Chemical Company Limited