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ChemicalBook >> CAS DataBase List >> I-SAP

I-SAP

I-SAP price.
  • $73 - $1097.25
  • Product name: I-SAP
  • CAS: 133538-58-6
  • MF: C22H30INO4S
  • MW: 531.45
  • EINECS:
  • MDL Number:MFCD00216083
  • Synonyms:THROMBOXANE A2;I-SAP;IODOPHENYL SULFONYL AMINO PINANE;[3S-[1ALPHA,2ALPHA,3BETA-5ALPHA]]-7-[3-[[(4-IODOPHENYL)SULFONYL]AMINO]-6,6-DIMETHYLBICYCLO[3.1.1]HEPT-2-YL]-5Z-HEPTENOIC ACID;[3S-[1alpha,3beta-5alpha]]-7-[3-[[(4-Ifodophenyl)sulfonyl]amino]-6,6-dimethylbicyclo[3.1.1]hept-2-yl]-5Z-heptenoic acid;7-(6,6-dimethyl-3-(4-iodobenzenesulfonylamino)bicyclo(3.1.1.)hept-2-yl)-5-heptenoic acid;SZNMERGTFJHNSM-JAWYFFTGSA-N;I SAP,ISAP
6 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
Package
  • 100μg
  • 500μg
  • 0.001g
  • 1mg
  • ManufacturerAHH
  • Product numberMT-15685
  • Product description[3S-[1alpha,3beta-5alpha]]-7-[3-[[(4-Ifodophenyl)sulfonyl]amino]6,6-dimethylbicyclo[3.1.1]hept-2-yl]-5Z-heptenoicacid 98%
  • Packaging0.001g
  • Price$298
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1803AH
  • Product descriptionI-SAP
  • Packaging1mg
  • Price$737
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0290099
  • Product description[3S-[1ALPHA,3BETA-5ALPHA]]-7-[3-[[(4-IODOPHENYL)SULFONYL]AMINO]-6,6-DIMETHYLBICYCLO[3.1.1]HEPT-2-YL]-5Z-HEPTENOIC ACID 98.00%
  • Packaging1MG
  • Price$1097.25
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19021
  • Product descriptionI-SAP ≥98%
  • Packaging100μg
  • Price$73
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19021
  • Product descriptionI-SAP ≥98%
  • Packaging500μg
  • Price$324
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19021
  • Product descriptionI-SAP ≥98%
  • Packaging1mg
  • Price$575
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-15685 [3S-[1alpha,3beta-5alpha]]-7-[3-[[(4-Ifodophenyl)sulfonyl]amino]6,6-dimethylbicyclo[3.1.1]hept-2-yl]-5Z-heptenoicacid 98% 0.001g $298 2021-12-16 Buy
AK Scientific 1803AH I-SAP 1mg $737 2021-12-16 Buy
American Custom Chemicals Corporation CHM0290099 [3S-[1ALPHA,3BETA-5ALPHA]]-7-[3-[[(4-IODOPHENYL)SULFONYL]AMINO]-6,6-DIMETHYLBICYCLO[3.1.1]HEPT-2-YL]-5Z-HEPTENOIC ACID 98.00% 1MG $1097.25 2021-12-16 Buy
Cayman Chemical 19021 I-SAP ≥98% 100μg $73 2024-03-01 Buy
Cayman Chemical 19021 I-SAP ≥98% 500μg $324 2024-03-01 Buy
Cayman Chemical 19021 I-SAP ≥98% 1mg $575 2024-03-01 Buy

Properties

Boiling point :606.3±61.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: >50 mg/ml (from Pinane TXA2); DMSO: >25 mg/ml (from Pinane TXA2); Ethanol: >100 mg/ml (from Pinane TXA2); PBS pH 7.2: >100 μg/ml (from Pinane TXA2)
pka :4.76±0.10(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

I-SAP is a high affinity TP receptor antagonist. At physiologic pH, I-SAP produces platelet shape change, but not aggregation, with an EC50 value of 9.7 nM. I-SAP binds to human platelets with the maximum binding obtained between pH 6.5 and pH 7.4. In washed human platelets, the Kd for I-SAP is 468 pM at pH 7.4 and 490 pM at pH 6.5.

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