INCB8761(PF-4136309)
- $32 - $2836
- Product name: INCB8761(PF-4136309)
- CAS: 1341224-83-6
- MF: C29H31F3N6O3
- MW: 568.59
- EINECS:
- MDL Number:
- Synonyms:INCB8761(PF-4136309);NCB8761(PF-4136309);PF-04136309(INCB-8761);Benzamide, N-[2-[(3S)-3-[[trans-4-hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-3-(trifluoromethyl)-;EOS-61910;N-(2-((S)-3-(((1r,4S)-4-hydroxy-4-(5-(pyrimidin-2-yl) yridine-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide;ZNSVOHSYDRPBGI-LXWOLXCRSA-N;N-(2-((S)-3-(((1R,4S)-4-HYDROXY-4-(5-(PYRIMIDIN-2-YL)
29 prices
Selected condition:
Brand
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- BLDpharm
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
Package
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAmbeed
- Product numberA733437
- Product descriptionN-(2-((S)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide 98+%
- Packaging10mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA733437
- Product descriptionN-(2-((S)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide 98+%
- Packaging25mg
- Price$203
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA733437
- Product descriptionN-(2-((S)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide 98+%
- Packaging50mg
- Price$305
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA733437
- Product descriptionN-(2-((S)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide 98+%
- Packaging100mg
- Price$452
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA733437
- Product descriptionN-(2-((S)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide 98+%
- Packaging250mg
- Price$731
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA733437
- Product descriptionN-(2-((S)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide 98+%
- Packaging1g
- Price$2836
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0028188
- Product descriptionPF-4136309 95.00%
- Packaging5MG
- Price$496.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3495
- Product descriptionINCB8761(PF-4136309)
- Packaging5mg
- Price$252
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3495
- Product descriptionINCB8761(PF-4136309)
- Packaging10mg
- Price$425
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3495
- Product descriptionINCB8761(PF-4136309)
- Packaging50mg
- Price$1260
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3495
- Product descriptionINCB8761(PF-4136309)
- Packaging100mg
- Price$2394
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFI104116
- Product descriptionINCB 8761
- Packaging10mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFI104116
- Product descriptionINCB 8761
- Packaging50mg
- Price$787.5
- Updated2021-12-16
- Buy
- ManufacturerBLDpharm
- Product numberBD630144
- Product descriptionN-(2-((S)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide 98+%
- Packaging10mg
- Price$271
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21965
- Product descriptionINCB 8761
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21965
- Product descriptionINCB 8761
- Packaging5mg
- Price$139
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Ambeed | A733437 | N-(2-((S)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide 98+% | 10mg | $108 | 2021-12-16 | Buy |
Ambeed | A733437 | N-(2-((S)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide 98+% | 25mg | $203 | 2021-12-16 | Buy |
Ambeed | A733437 | N-(2-((S)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide 98+% | 50mg | $305 | 2021-12-16 | Buy |
Ambeed | A733437 | N-(2-((S)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide 98+% | 100mg | $452 | 2021-12-16 | Buy |
Ambeed | A733437 | N-(2-((S)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide 98+% | 250mg | $731 | 2021-12-16 | Buy |
Ambeed | A733437 | N-(2-((S)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide 98+% | 1g | $2836 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0028188 | PF-4136309 95.00% | 5MG | $496.5 | 2021-12-16 | Buy |
ApexBio Technology | A3495 | INCB8761(PF-4136309) | 5mg | $252 | 2021-12-16 | Buy |
ApexBio Technology | A3495 | INCB8761(PF-4136309) | 10mg | $425 | 2021-12-16 | Buy |
ApexBio Technology | A3495 | INCB8761(PF-4136309) | 50mg | $1260 | 2021-12-16 | Buy |
ApexBio Technology | A3495 | INCB8761(PF-4136309) | 100mg | $2394 | 2021-12-16 | Buy |
Biosynth Carbosynth | FI104116 | INCB 8761 | 10mg | $225 | 2021-12-16 | Buy |
Biosynth Carbosynth | FI104116 | INCB 8761 | 50mg | $787.5 | 2021-12-16 | Buy |
BLDpharm | BD630144 | N-(2-((S)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide 98+% | 10mg | $271 | 2021-12-16 | Buy |
Cayman Chemical | 21965 | INCB 8761 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 21965 | INCB 8761 | 5mg | $139 | 2024-03-01 | Buy |
Properties
Boiling point :712.2±60.0 °C(Predicted)
Density :1.40±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :solid
pka :13.17±0.46(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Density :1.40±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :solid
pka :13.17±0.46(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
Symbol(GHS): | ||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | |||||||||||||||||||||||||||||||||||
Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
PF-4136309 is a chemokine (C-C motif) receptor 2 (CCR2) antagonist (IC50s = 5.2, 13, and 17 nM for the human, rat, and mouse receptors, respectively). It also inhibits the voltage-gated potassium channel subtype Kv11.1 by 35% when used at a concentration of 10 μM. PF-4136309 decreases isolated human monocyte chemotaxis induced by chemokine (C-C motif) ligand 2 (CCL2) with an IC50 value of 3.9 nM.Related product price
- Telatinib
$28-8100 - (+)-Camptothecin
$18-1900.44 - Vorinostat
$8-3980
Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Career Henan Chemica Co
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Henan Fengda Chemical Co., Ltd
Shanghai Acmec Biochemical Technology Co., Ltd.