INDY
|
- $30 - $931
- Product name: INDY
- CAS: 1169755-45-6
- MF: C12H13NO2S
- MW: 235.3
- EINECS:
- MDL Number:MFCD28100814
- Synonyms:INDY;(1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone;(Z)-1-(3-Ethyl-5-hydroxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one;2-Propanone, 1-(3-ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-, (1Z)-;(1Z)-1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2-ylidene)propan-2-one;(1Z)-1-(3-Ethyl-5-hydroxy-1,3-benzothiazol-2(3H)-ylidene)acetone
18 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5MG
- 25mg
- 10
- 1mg
- 10mg
- 100mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3665-M025
- Product descriptionINDY ≥98%(HPLC)
- Packaging25mg
- Price$320
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5281
- Product descriptionINDY
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5281
- Product descriptionINDY
- Packaging100mg
- Price$931
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0009875
- Product descriptionINDY 95.00%
- Packaging5MG
- Price$501.14
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5790
- Product descriptionINDY
- Packaging5mg
- Price$103
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5790
- Product descriptionINDY
- Packaging10mg
- Price$187
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5790
- Product descriptionINDY
- Packaging25mg
- Price$422
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number23895
- Product descriptionINDY ≥98%
- Packaging1mg
- Price$30
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23895
- Product descriptionINDY ≥98%
- Packaging5mg
- Price$75
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23895
- Product descriptionINDY ≥98%
- Packaging10mg
- Price$134
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23895
- Product descriptionINDY ≥98%
- Packaging25mg
- Price$296
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0028909
- Product descriptionINDY
- Packaging5mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0028909
- Product descriptionINDY
- Packaging10mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1011
- Product descriptionINDY ≥98% (HPLC)
- Packaging5mg
- Price$103
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1011
- Product descriptionINDY ≥98% (HPLC)
- Packaging25mg
- Price$334
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number4997
- Product descriptionINDY ≥98%(HPLC)
- Packaging10
- Price$181
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3665-M025 | INDY ≥98%(HPLC) | 25mg | $320 | 2021-12-16 | Buy |
| AK Scientific | SYN5281 | INDY | 10mg | $160 | 2021-12-16 | Buy |
| AK Scientific | SYN5281 | INDY | 100mg | $931 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0009875 | INDY 95.00% | 5MG | $501.14 | 2021-12-16 | Buy |
| ApexBio Technology | B5790 | INDY | 5mg | $103 | 2021-12-16 | Buy |
| ApexBio Technology | B5790 | INDY | 10mg | $187 | 2021-12-16 | Buy |
| ApexBio Technology | B5790 | INDY | 25mg | $422 | 2021-12-16 | Buy |
| Cayman Chemical | 23895 | INDY ≥98% | 1mg | $30 | 2024-03-01 | Buy |
| Cayman Chemical | 23895 | INDY ≥98% | 5mg | $75 | 2024-03-01 | Buy |
| Cayman Chemical | 23895 | INDY ≥98% | 10mg | $134 | 2024-03-01 | Buy |
| Cayman Chemical | 23895 | INDY ≥98% | 25mg | $296 | 2024-03-01 | Buy |
| ChemScene | CS-0028909 | INDY | 5mg | $270 | 2021-12-16 | Buy |
| ChemScene | CS-0028909 | INDY | 10mg | $450 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML1011 | INDY ≥98% (HPLC) | 5mg | $103 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1011 | INDY ≥98% (HPLC) | 25mg | $334 | 2024-03-01 | Buy |
| Tocris | 4997 | INDY ≥98%(HPLC) | 10 | $181 | 2021-12-16 | Buy |
Properties
Boiling point :409.2±45.0 °C(Predicted)
Density :1.337±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :9.67±0.20(Predicted)
form :powder
color :white to beige
Density :1.337±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :9.67±0.20(Predicted)
form :powder
color :white to beige
Safety Information
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Description
INDY is an ATP-competitive inhibitor of dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A; Ki = 180 nM; IC50 = 240 nM). It is selective for DYRK1A over monoamine oxidase (MAO) A and B at concentrations up to 100 μM. INDY inhibits DYRK1A phosphorylation of tau in COS-7 cells expressing EGFP-DYRK1A and EGFP-tau in a concentration-dependent manner. It also restores signaling through nuclear factory of activated T cells (NFAT) and NFAT-dependent transcription in HEK293 cells overexpressing DYRK1A. In vivo, INDY reverses developmental deformities induced by DYRK1A overexpression in X. laevis embryos. INDY also induces proliferation of human and rat β-cells and increases insulin secretion by human islets in vitro.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
TargetMol Chemicals Inc.
Nantong HI-FUTURE Biology Co., Ltd.
Aladdin Scientific
Shanghai Lollane Biological Technology Co.,Ltd.
Guangzhou Zhiya Chemdrugs Co.,Ltd
EMMX Biotechnology LLC
Shanghai EFE Biological Technology Co., Ltd.
TaiChem Taizhou Limited
Shanghai Changyan Chem & Tech Co., Ltd.