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ChemicalBook >> CAS DataBase List >> Irbesartan

Irbesartan

Irbesartan price.
  • $5 - $1200
  • Product name: Irbesartan
  • CAS: 138402-11-6
  • MF: C25H28N6O
  • MW: 428.53
  • EINECS:604-078-2
  • MDL Number:MFCD00864464
  • Synonyms:2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO[4.4]NON-1-EN-4-ONE;IRBESARTAN;BMS-186295;APROVEL;1,3-Diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-;2-Isopropryl-4-methylthiazole;2-butyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one;2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
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  • y0001166
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  • ManufacturerAmbeed
  • Product numberA262974
  • Product descriptionIrbesartan 95%
  • Packaging250mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA262974
  • Product descriptionIrbesartan 95%
  • Packaging1g
  • Price$6
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA262974
  • Product descriptionIrbesartan 95%
  • Packaging5g
  • Price$11
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA262974
  • Product descriptionIrbesartan 95%
  • Packaging10g
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA262974
  • Product descriptionIrbesartan 95%
  • Packaging25g
  • Price$42
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA262974
  • Product descriptionIrbesartan 95%
  • Packaging100g
  • Price$115
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA262974
  • Product descriptionIrbesartan 95%
  • Packaging500g
  • Price$354
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003025
  • Product descriptionIRBESARTAN 95.00%
  • Packaging1G
  • Price$130.2
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5970
  • Product descriptionIrbesartan
  • Packaging25mg
  • Price$80
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS498571
  • Product descriptionIrbesartan 95%
  • Packaging1g
  • Price$6
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS498571
  • Product descriptionIrbesartan 95%
  • Packaging5g
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS498571
  • Product descriptionIrbesartan 95%
  • Packaging10g
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS498571
  • Product descriptionIrbesartan 95%
  • Packaging25g
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS498571
  • Product descriptionIrbesartan 95%
  • Packaging100g
  • Price$114
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS498571
  • Product descriptionIrbesartan 95%
  • Packaging500g
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number40298
  • Product descriptionIRBESARTAN 97%
  • Packaging10/ G
  • Price$50
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A262974 Irbesartan 95% 250mg $5 2021-12-16 Buy
Ambeed A262974 Irbesartan 95% 1g $6 2021-12-16 Buy
Ambeed A262974 Irbesartan 95% 5g $11 2021-12-16 Buy
Ambeed A262974 Irbesartan 95% 10g $19 2021-12-16 Buy
Ambeed A262974 Irbesartan 95% 25g $42 2021-12-16 Buy
Ambeed A262974 Irbesartan 95% 100g $115 2021-12-16 Buy
Ambeed A262974 Irbesartan 95% 500g $354 2021-12-16 Buy
American Custom Chemicals Corporation API0003025 IRBESARTAN 95.00% 1G $130.2 2021-12-16 Buy
ApexBio Technology A5970 Irbesartan 25mg $80 2021-12-16 Buy
Arctom AS498571 Irbesartan 95% 1g $6 2021-12-16 Buy
Arctom AS498571 Irbesartan 95% 5g $11 2021-12-16 Buy
Arctom AS498571 Irbesartan 95% 10g $19 2021-12-16 Buy
Arctom AS498571 Irbesartan 95% 25g $42 2021-12-16 Buy
Arctom AS498571 Irbesartan 95% 100g $114 2021-12-16 Buy
Arctom AS498571 Irbesartan 95% 500g $350 2021-12-16 Buy
AstaTech 40298 IRBESARTAN 97% 10/ G $50 2021-12-16 Buy

Properties

Melting point :180-181°C
Boiling point :648.6±65.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >25mg/mL
pka :4.16±0.10(Predicted)
form :powder
color :white to off-white
Merck :14,5083
BCS Class :2
CAS DataBase Reference :138402-11-6(CAS DataBase Reference)
EPA Substance Registry System :1,3-Diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (138402-11-6)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

Angiotensin II receptor blockers (ARBs) act as cardioprotective agents that are effective in hypertension, left ventricular hypertrophy, postmyocardial infarction, and heart failure. Irbesartan is an ARB with a high affinity for the AT1 receptor (Ki = 2.7 nM) and exceptionally high bioavailability (60-80%). It is an insurmountable antagonist of AT1, as its antagonism of this receptor cannot be overcome by increasing concentrations of angiotensin II. Irbesartan effectively reduces blood pressure alone but may also be used in combination with a diuretic, such as hydrochlorothiazide. As angiotensin II contributes in diverse ways to endothelial dysfunction, irbesartan and other ARBs directly protect the vascular endothelium. Other pathologies, including diabetes and kidney disease, also benefit from the cardiovascular and endothelial protective actions of ARBs like irbesartan.

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