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ChemicalBook >> CAS DataBase List >> Ivosidenib

Ivosidenib

Ivosidenib price.
  • $32 - $1200
  • Product name: Ivosidenib
  • CAS: 1448347-49-6
  • MF: C28H22ClF3N6O3
  • MW: 582.96
  • EINECS:-0
  • MDL Number:MFCD29036964
  • Synonyms:RG120;RG120 100MG;(S)-N-((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide;(2S)-1-(4-Cyano-2-pyridinyl)-5-oxo-L-prolyl-2-(2-chlorophenyl)-N-(3,3-difluorocyclobutyl)-N2-(5-fluoro-3-pyridinyl)glycinamide;Glycinamide, 1-(4-cyano-2-pyridinyl)-5-oxo-L-prolyl-2-(2-chlorophenyl)-N-(3,3-difluorocyclobutyl)-N2-(5-fluoro-3-pyridinyl)-, (2S)-;AG120;AG 120;CS-1721;EOS-60845
24 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 1mg
  • 2mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number0862DV
  • Product descriptionIvosidenib
  • Packaging25mg
  • Price$387
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004922
  • Product descriptionIVOSIDENIB 95.00%
  • Packaging5MG
  • Price$502.8
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7805
  • Product descriptionAG-120
  • Packaging5mg
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7805
  • Product descriptionAG-120
  • Packaging25mg
  • Price$334
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2746
  • Product descriptionAG-120-Ivosidenib 99%
  • Packaging10mg
  • Price$137.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA145491
  • Product descriptionAG 120
  • Packaging2mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA145491
  • Product descriptionAG 120
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA145491
  • Product descriptionAG 120
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA145491
  • Product descriptionAG 120
  • Packaging25mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA145491
  • Product descriptionAG 120
  • Packaging50mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19894
  • Product descriptionAG-120 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19894
  • Product descriptionAG-120 ≥98%
  • Packaging5mg
  • Price$100
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19894
  • Product descriptionAG-120 ≥98%
  • Packaging10mg
  • Price$184
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19894
  • Product descriptionAG-120 ≥98%
  • Packaging25mg
  • Price$381
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5122
  • Product descriptionIvosidenib 99.78%
  • Packaging5mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5122
  • Product descriptionIvosidenib 99.78%
  • Packaging10mg
  • Price$147
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0862DV Ivosidenib 25mg $387 2021-12-16 Buy
American Custom Chemicals Corporation INB0004922 IVOSIDENIB 95.00% 5MG $502.8 2021-12-16 Buy
ApexBio Technology B7805 AG-120 5mg $103 2021-12-16 Buy
ApexBio Technology B7805 AG-120 25mg $334 2021-12-16 Buy
Axon Medchem Axon2746 AG-120-Ivosidenib 99% 10mg $137.5 2021-12-16 Buy
Biosynth Carbosynth FA145491 AG 120 2mg $60 2021-12-16 Buy
Biosynth Carbosynth FA145491 AG 120 5mg $100 2021-12-16 Buy
Biosynth Carbosynth FA145491 AG 120 10mg $150 2021-12-16 Buy
Biosynth Carbosynth FA145491 AG 120 25mg $250 2021-12-16 Buy
Biosynth Carbosynth FA145491 AG 120 50mg $350 2021-12-16 Buy
Cayman Chemical 19894 AG-120 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 19894 AG-120 ≥98% 5mg $100 2024-03-01 Buy
Cayman Chemical 19894 AG-120 ≥98% 10mg $184 2024-03-01 Buy
Cayman Chemical 19894 AG-120 ≥98% 25mg $381 2024-03-01 Buy
ChemScene CS-5122 Ivosidenib 99.78% 5mg $80 2021-12-16 Buy
ChemScene CS-5122 Ivosidenib 99.78% 10mg $147 2021-12-16 Buy

Properties

Melting point :151-173°C
Boiling point :854.3±65.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :11.58±0.40(Predicted)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) that specifically inhibits a mutated form of IDH1 in the cytoplasm, preventing the formation of 2-hydroxyglutarate. AG-120 may induce cellular differentiation as well as inhibit proliferation in IDH1-expressing tumor cells.

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