JASPLAKINOLIDE
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- $169 - $750
- Product name: JASPLAKINOLIDE
- CAS: 102396-24-7
- MF: C36H45BrN4O6
- MW: 709.67
- EINECS:
- MDL Number:MFCD00873735
- Synonyms:JASPLAKINOLIDE;JASPLAKINOLIDE, JASPIS JOHNSTONI;(3S,6R,9R,13S,15R,16E,19S)-3,5,13,15,17,19-Hexamethyl-6-[(2-bromo-1H-indole-3-yl)methyl]-9-(4-hydroxyphenyl)-12-oxa-2,5,8-triazacyclononadeca-16-ene-1,4,7,11-tetraone;[3S,6R,9R,13S,15R,19S,16E,(+)]-6-[(2-Bromo-1H-indol-3-yl)methyl]-9-(4-hydroxyphenyl)-3,5,13,15,17,19-hexamethyl-2,5,8-triaza-12-oxacyclononadecan-16-ene-1,4,7,11-tetrone;NSC 613009;Jasplakinolide, Jaspis johnstoni - CAS 102396-24-7 - Calbiochem;Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl];GQWYWHOHRVVHAP-DHKPLNAMSA-N
12 prices
Selected condition:
Brand
- Adipogen Life Sciences
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50ug
- 50μg
- 100ug
- 100μg
- 100U
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0037-C100
- Product descriptionJasplakinolide(highpurity) ≥98%(HPLC)
- Packaging100μg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7189
- Product descriptionJasplakinolide
- Packaging50ug
- Price$229
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7189
- Product descriptionJasplakinolide
- Packaging100ug
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11705
- Product descriptionJasplakinolide ≥98%
- Packaging50μg
- Price$169
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11705
- Product descriptionJasplakinolide ≥98%
- Packaging100μg
- Price$287
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0012978
- Product descriptionJasplakinolide ≥98.0%
- Packaging100ug
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberJ4580
- Product descriptionJasplakinolide ≥97% (HPLC)
- Packaging100μg
- Price$740
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number2792
- Product descriptionJasplakinolide ≥97%(HPLC)
- Packaging100U
- Price$374
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberJ210700
- Product descriptionJasplakinolide
- Packaging100μg
- Price$235
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number044973
- Product descriptionJasplakinolide
- Packaging50ug
- Price$392
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number164561
- Product descriptionJasplakinolide
- Packaging50ug
- Price$418
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number255548
- Product descriptionJasplakinolide
- Packaging100ug
- Price$631
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | AG-CN2-0037-C100 | Jasplakinolide(highpurity) ≥98%(HPLC) | 100μg | $280 | 2021-12-16 | Buy |
ApexBio Technology | B7189 | Jasplakinolide | 50ug | $229 | 2021-12-16 | Buy |
ApexBio Technology | B7189 | Jasplakinolide | 100ug | $390 | 2021-12-16 | Buy |
Cayman Chemical | 11705 | Jasplakinolide ≥98% | 50μg | $169 | 2024-03-01 | Buy |
Cayman Chemical | 11705 | Jasplakinolide ≥98% | 100μg | $287 | 2024-03-01 | Buy |
ChemScene | CS-0012978 | Jasplakinolide ≥98.0% | 100ug | $750 | 2021-12-16 | Buy |
Sigma-Aldrich | J4580 | Jasplakinolide ≥97% (HPLC) | 100μg | $740 | 2024-03-01 | Buy |
Tocris | 2792 | Jasplakinolide ≥97%(HPLC) | 100U | $374 | 2021-12-16 | Buy |
TRC | J210700 | Jasplakinolide | 100μg | $235 | 2021-12-16 | Buy |
Usbiological | 044973 | Jasplakinolide | 50ug | $392 | 2021-12-16 | Buy |
Usbiological | 164561 | Jasplakinolide | 50ug | $418 | 2021-12-16 | Buy |
Usbiological | 255548 | Jasplakinolide | 100ug | $631 | 2021-12-16 | Buy |
Properties
Melting point :110℃ (decomposition)
storage temp. :-20°C
solubility :DMSO: >2mg/mL
form :Off-white solid
color :off white to beige
storage temp. :-20°C
solubility :DMSO: >2mg/mL
form :Off-white solid
color :off white to beige
Safety Information
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Description
Jasplakinolide is a natural macrocyclic peptide first isolated from a marine sponge. It potently inhibits the proliferation of PC3 prostate carcinoma cells (IC50 = 35 nM) by binding F-actin (KD = 15 nM). This binding of jasplakinolide to actin, which is competitive with phalloidin, stabilizes actin filaments in vitro but disrupts actin filaments and induces irregular polymerization of monomeric actin in vivo. This compound is used to investigate the role of actin in diverse cellular roles, such as motility, transport, and development.More related product prices
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