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ChemicalBook >> CAS DataBase List >> JTT-705

JTT-705

JTT-705 price.
  • $49 - $28378.35
  • Product name: JTT-705
  • CAS: 211513-37-0
  • MF: C23H35NO2S
  • MW: 389.59
  • EINECS:
  • MDL Number:MFCD06407886
  • Synonyms:JTT-705;Dalcetrapib;Unii-3D050liq3h;2-Methylpropanethioic acid S-[2-[1-(2-ethylbutyl)cyclohexylcarboxamido]phenyl] ester;Thioisobutyric acid S-(2-{[1-(2-ethyl-butyl)-cyclohexanecarbonyl]-aMino}-phenyl) ester;S-2-(1-(2-ethylbutyl)cyclohexanecarboxamido)phenyl 2-methylpropanethioate;2-Methylpropanethioic acid S-[2-[1-(2-ethylbutyl)cyclohexylcarboxamido]phenyl] ester Dalcetrapib (JTT-705, RO4607381);Dalcetrapib 2-Methylpropanethioic acid S-[2-[1-(2-ethylbutyl)cyclohexylcarboxamido]phenyl] ester
35 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • Matrix Scientific
  • TRC
  • Usbiological
Package
  • 1MG
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • 1g
  • 5G
  • 10G
  • ManufacturerAK Scientific
  • Product numberY0342
  • Product descriptionDalcetrapib
  • Packaging1g
  • Price$2901
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA162985
  • Product descriptionDalcetrapib 98+%
  • Packaging5mg
  • Price$315
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA162985
  • Product descriptionDalcetrapib 98+%
  • Packaging10mg
  • Price$472
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA162985
  • Product descriptionDalcetrapib 98+%
  • Packaging25mg
  • Price$801
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003063
  • Product descriptionDALCETRAPIB 95.00%
  • Packaging1MG
  • Price$153.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003063
  • Product descriptionDALCETRAPIB 95.00%
  • Packaging1G
  • Price$9702
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003063
  • Product descriptionDALCETRAPIB 95.00%
  • Packaging5G
  • Price$21144.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003063
  • Product descriptionDALCETRAPIB 95.00%
  • Packaging10G
  • Price$28378.35
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4376
  • Product descriptionDalcetrapib(JTT-705,RO4607381)
  • Packaging10mM(in 1mL DMSO)
  • Price$182
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4376
  • Product descriptionDalcetrapib(JTT-705,RO4607381)
  • Packaging5mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4376
  • Product descriptionDalcetrapib(JTT-705,RO4607381)
  • Packaging10mg
  • Price$329
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4376
  • Product descriptionDalcetrapib(JTT-705,RO4607381)
  • Packaging50mg
  • Price$1169
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4376
  • Product descriptionDalcetrapib(JTT-705,RO4607381)
  • Packaging100mg
  • Price$1729
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS459331
  • Product descriptionDalcetrapib ≥98%
  • Packaging50mg
  • Price$1031
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146150
  • Product descriptionDalcetrapib (JTT-705) >98%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146150
  • Product descriptionDalcetrapib (JTT-705) >98%
  • Packaging250mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0342 Dalcetrapib 1g $2901 2021-12-16 Buy
Ambeed A162985 Dalcetrapib 98+% 5mg $315 2021-12-16 Buy
Ambeed A162985 Dalcetrapib 98+% 10mg $472 2021-12-16 Buy
Ambeed A162985 Dalcetrapib 98+% 25mg $801 2021-12-16 Buy
American Custom Chemicals Corporation API0003063 DALCETRAPIB 95.00% 1MG $153.3 2021-12-16 Buy
American Custom Chemicals Corporation API0003063 DALCETRAPIB 95.00% 1G $9702 2021-12-16 Buy
American Custom Chemicals Corporation API0003063 DALCETRAPIB 95.00% 5G $21144.3 2021-12-16 Buy
American Custom Chemicals Corporation API0003063 DALCETRAPIB 95.00% 10G $28378.35 2021-12-16 Buy
ApexBio Technology A4376 Dalcetrapib(JTT-705,RO4607381) 10mM(in 1mL DMSO) $182 2021-12-16 Buy
ApexBio Technology A4376 Dalcetrapib(JTT-705,RO4607381) 5mg $189 2021-12-16 Buy
ApexBio Technology A4376 Dalcetrapib(JTT-705,RO4607381) 10mg $329 2021-12-16 Buy
ApexBio Technology A4376 Dalcetrapib(JTT-705,RO4607381) 50mg $1169 2021-12-16 Buy
ApexBio Technology A4376 Dalcetrapib(JTT-705,RO4607381) 100mg $1729 2021-12-16 Buy
Arctom AS459331 Dalcetrapib ≥98% 50mg $1031 2021-12-16 Buy
Biorbyt Ltd orb146150 Dalcetrapib (JTT-705) >98% 100mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb146150 Dalcetrapib (JTT-705) >98% 250mg $1208.7 2021-12-16 Buy

Properties

Melting point :63-63.5 °C
Boiling point :528.9±33.0 °C(Predicted)
Density :1.06±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in H2O; ≥12.7 mg/mL in DMSO; ≥80.2 mg/mL in EtOH
form :solid
pka :13.95±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:

Description

Cholesteryl ester transfer protein (CETP) is an exchange protein which transfers cholesteryl esters from HDL to VLDL, IDL, and LDL in exchange for triglycerides. Dalcetrapib is an inhibitor of CETP that exhibits an IC50 value of 9 μM for plasma CETP in rabbits. Inhibition of CETP by dalcetrapib in rabbits given an atherogenic diet leads to elevation of HDL, decreased VLDL, and attenuation of the induced atherosclerosis. In human subjects, dalcetrapib also inhibits CETP activity and increases plasma HDL levels but it does not reduce the risk of recurrent cardiovascular events.

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