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ChemicalBook >> CAS DataBase List >> JW 480

JW 480

JW 480 price.
  • $56 - $1090.27
  • Product name: JW 480
  • CAS: 1354359-53-7
  • MF: C22H23NO2
  • MW: 333.42
  • EINECS:
  • MDL Number:MFCD20926355
  • Synonyms:2-Isopropylphenyl (2-(naphthalen-2-yl)ethyl)carbamate;Cancer Hydrolase KIAA1363 Inhibitor, JW480 ;JW 480;Cancer Hydrolase KIAA1363 Inhibitor, JW480 - CAS 1354359-53-7 - Calbiochem;PCNJGBMWAZRVEA-UHFFFAOYSA-N;Carbamic acid, N-[2-(2-naphthalenyl)ethyl]-, 2-(1-methylethyl)phenyl ester;JW480,JW-480,JW 480,Inhibitor,inhibit
14 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10MG
  • 25mg
  • 50MG
  • ManufacturerAK Scientific
  • Product number3271DN
  • Product description2-Isopropylphenyl(2-(naphthalen-2-yl)ethyl)carbamate
  • Packaging5mg
  • Price$159
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3271DN
  • Product description2-Isopropylphenyl(2-(naphthalen-2-yl)ethyl)carbamate
  • Packaging25mg
  • Price$367
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010265
  • Product description2-ISOPROPYLPHENYL(2-(NAPHTHALEN-2-YL)ETHYL)CARBAMATE 95.00%
  • Packaging10MG
  • Price$721.59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010265
  • Product description2-ISOPROPYLPHENYL(2-(NAPHTHALEN-2-YL)ETHYL)CARBAMATE 95.00%
  • Packaging50MG
  • Price$1090.27
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5556
  • Product descriptionJW480
  • Packaging10mg
  • Price$182
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5556
  • Product descriptionJW480
  • Packaging50mg
  • Price$763
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10879
  • Product descriptionJW 480 ≥98%
  • Packaging5mg
  • Price$56
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10879
  • Product descriptionJW 480 ≥98%
  • Packaging10mg
  • Price$105
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10879
  • Product descriptionJW 480 ≥98%
  • Packaging25mg
  • Price$241
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10879
  • Product descriptionJW 480 ≥98%
  • Packaging50mg
  • Price$429
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0792
  • Product descriptionJW480 ≥98% (HPLC)
  • Packaging5mg
  • Price$98.4
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number420175
  • Product descriptionCancer Hydrolase KIAA1363 Inhibitor, JW480
  • Packaging10mg
  • Price$140
  • Updated2023-01-07
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0792
  • Product descriptionJW480 ≥98% (HPLC)
  • Packaging25mg
  • Price$482
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberJ211933
  • Product descriptionJW480
  • Packaging25mg
  • Price$175
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3271DN 2-Isopropylphenyl(2-(naphthalen-2-yl)ethyl)carbamate 5mg $159 2021-12-16 Buy
AK Scientific 3271DN 2-Isopropylphenyl(2-(naphthalen-2-yl)ethyl)carbamate 25mg $367 2021-12-16 Buy
American Custom Chemicals Corporation API0010265 2-ISOPROPYLPHENYL(2-(NAPHTHALEN-2-YL)ETHYL)CARBAMATE 95.00% 10MG $721.59 2021-12-16 Buy
American Custom Chemicals Corporation API0010265 2-ISOPROPYLPHENYL(2-(NAPHTHALEN-2-YL)ETHYL)CARBAMATE 95.00% 50MG $1090.27 2021-12-16 Buy
ApexBio Technology B5556 JW480 10mg $182 2021-12-16 Buy
ApexBio Technology B5556 JW480 50mg $763 2021-12-16 Buy
Cayman Chemical 10879 JW 480 ≥98% 5mg $56 2024-03-01 Buy
Cayman Chemical 10879 JW 480 ≥98% 10mg $105 2024-03-01 Buy
Cayman Chemical 10879 JW 480 ≥98% 25mg $241 2024-03-01 Buy
Cayman Chemical 10879 JW 480 ≥98% 50mg $429 2024-03-01 Buy
Sigma-Aldrich SML0792 JW480 ≥98% (HPLC) 5mg $98.4 2024-03-01 Buy
Sigma-Aldrich 420175 Cancer Hydrolase KIAA1363 Inhibitor, JW480 10mg $140 2023-01-07 Buy
Sigma-Aldrich SML0792 JW480 ≥98% (HPLC) 25mg $482 2024-03-01 Buy
TRC J211933 JW480 25mg $175 2021-12-16 Buy

Properties

storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :White powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P501 Dispose of contents/container to..…

Description

The transmembrane enzyme KIAA1363 (also known as AADACL1) controls the production of the monoalkylglycerol ether (MAGE) class of neutral ether lipids (NELs) in cancer cells. Hyperactivity of this 2-acetyl MAGE hydrolase is associated with tumor cell migration, invasion, survival, and growth. JW 480 acts as a potent, selective inhibitor of KIAA1361 (IC50s = 20 nM in mouse brain membrane proteomes and 6-12 nM in human PC3 prostate cancer cell proteomes), showing little cross reactivity with hormone-sensitive lipase, acetylcholinesterase, or other serine hydrolases. JW 480 is active in vivo, reducing PC3 tumor xenograft growth in immune-deficient SCID mice at an oral dose of 80 mg/kg.