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ChemicalBook >> CAS DataBase List >> KPT-330

KPT-330

KPT-330 price.
  • $29 - $2691.1
  • Product name: KPT-330
  • CAS: 1393477-72-9
  • MF: C17H11F6N7O
  • MW: 443.31
  • EINECS:
  • MDL Number:MFCD27987944
  • Synonyms:KPT-330;(2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyrazinyl)hydrazide;Selinexor (KPT-330);(Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide;2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyrazinyl)hydrazide, (2Z)-;Aloradine;KPT330,Selinexor;(KPT330)(Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide
16 prices
Selected condition:
Brand
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
Package
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1000mg
  • 10mM(in 1mL DMSO)
  • ManufacturerApexBio Technology
  • Product numberB1464
  • Product descriptionKPT-330
  • Packaging5mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1464
  • Product descriptionKPT-330
  • Packaging10mM(in 1mL DMSO)
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1464
  • Product descriptionKPT-330
  • Packaging50mg
  • Price$399
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60293
  • Product descriptionSelinexor(KPT-330) ≥98%
  • Packaging10mg
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180928
  • Product descriptionKPT-330(Selinexor) >98%
  • Packaging100mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180928
  • Product descriptionKPT-330(Selinexor) >98%
  • Packaging250mg
  • Price$1431.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180928
  • Product descriptionKPT-330(Selinexor) >98%
  • Packaging1000mg
  • Price$2691.1
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18127
  • Product descriptionKPT-330 ≥98%
  • Packaging50mg
  • Price$508
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18127
  • Product descriptionKPT-330 ≥98%
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18127
  • Product descriptionKPT-330 ≥98%
  • Packaging5mg
  • Price$94
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18127
  • Product descriptionKPT-330 ≥98%
  • Packaging1mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003643
  • Product descriptionKPT-330 98+%
  • Packaging50mg
  • Price$440
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003643
  • Product descriptionKPT-330 98+%
  • Packaging100mg
  • Price$838
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7067
  • Product descriptionKPT-330(Selinexor) >98%
  • Packaging100mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7067
  • Product descriptionKPT-330(Selinexor) >98%
  • Packaging250mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number46996
  • Product descriptionKPT330
  • Packaging50mg
  • Price$1025
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B1464 KPT-330 5mg $68 2021-12-16 Buy
ApexBio Technology B1464 KPT-330 10mM(in 1mL DMSO) $100 2021-12-16 Buy
ApexBio Technology B1464 KPT-330 50mg $399 2021-12-16 Buy
Arctom CFN60293 Selinexor(KPT-330) ≥98% 10mg $238 2021-12-16 Buy
Biorbyt Ltd orb180928 KPT-330(Selinexor) >98% 100mg $765 2021-12-16 Buy
Biorbyt Ltd orb180928 KPT-330(Selinexor) >98% 250mg $1431.4 2021-12-16 Buy
Biorbyt Ltd orb180928 KPT-330(Selinexor) >98% 1000mg $2691.1 2021-12-16 Buy
Cayman Chemical 18127 KPT-330 ≥98% 50mg $508 2021-12-16 Buy
Cayman Chemical 18127 KPT-330 ≥98% 10mg $160 2021-12-16 Buy
Cayman Chemical 18127 KPT-330 ≥98% 5mg $94 2021-12-16 Buy
Cayman Chemical 18127 KPT-330 ≥98% 1mg $29 2021-12-16 Buy
Crysdot CD31003643 KPT-330 98+% 50mg $440 2021-12-16 Buy
Crysdot CD31003643 KPT-330 98+% 100mg $838 2021-12-16 Buy
DC Chemicals DC7067 KPT-330(Selinexor) >98% 100mg $500 2021-12-16 Buy
DC Chemicals DC7067 KPT-330(Selinexor) >98% 250mg $950 2021-12-16 Buy
Medical Isotopes, Inc. 46996 KPT330 50mg $1025 2021-12-16 Buy

Properties

Density :1.55±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml). or in Ethanol (up to at least 25 mg/ml)
pka :9.74±0.43(Predicted)
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P322 Specific measures (see …on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

Selinexor (1393477-72-9) is a potent inhibitor of the nuclear export receptor, chromosome region maintenance 1 (CRM1; Exportin-1 (XPO1)). It exhibited potent growth suppression in various T-cell acute lymphoblastic leukemia (T-ALL) cells (IC50’s = 34-203 nM)1?and pancreatic cancer cells (IC50?~ 150 nM)2. Selinexor is being investigated as a possible chemotherapeutic in treating multiple types of cancer.3-8?Currently in clinical trials.

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